A1 vs. A2 Milk: Debunking Myths, Understanding Science, and Navigating Regulatory Shifts

A1 vs. A2 Milk: Debunking Myths, Understanding Science, and Navigating Regulatory Shifts

In recent years, the debate surrounding A1 and A2 milk has gained significant attention, not just among health-conscious consumers but also within regulatory circles. If you're unfamiliar with the differences between these two types of milk, or if you've been puzzled by the recent headlines regarding the Food Safety and Standards Authority of India (FSSAI) and its stance on A1 and A2 milk, this article aims to provide you with a clear and concise overview.

What are A1 and A2 Milk?

Milk is a staple in many diets around the world, but not all milk is created equal. The primary difference between A1 and A2 milk lies in a specific protein called beta-casein, which constitutes about 28% of the total protein in cow's milk.

  • A1 Milk: Contains the A1 variant of beta-casein. This type of milk is predominantly found in cows of European origin, such as Holstein, Friesian, and Ayrshire breeds.
  • A2 Milk: Contains the A2 variant of beta-casein, which is more common in older/ Zebu/ native Indian cows like Gir, Sindhi, Sahiwal.

The significance of this distinction stems from the digestion process. Some studies suggest that the A1 protein can break down into a peptide called beta-casomorphin-7 (BCM-7), which may be linked to digestive discomfort and other health issues in certain individuals.

A2 milk, on the other hand, does not produce BCM-7, and thus is easier on the digestive system.

Myths and Facts About A2 Milk

Myth 1: A2 Milk is Lactose-Free

Fact: A2 milk contains the same amount of lactose as regular milk. It is the type of protein (A2 beta-casein) that differs, not the lactose content.

Myth 2: A2 Milk is a New Invention

Fact: A2 milk is not a new invention. Historically, all cows produced only A2 beta-casein. The A1 variant appeared due to a genetic mutation in European herds thousands of years ago. It is interesting to note that all mammals other than A1 cows, produce A2 milk. So yes, Goat milk, Buffalo milk and human milk for that matter is A2.

Myth 3: A2 Milk is Just a Marketing Gimmick

Fact: There is scientific evidence suggesting that A2 milk may be easier to digest for some people compared to regular milk containing A1 beta-casein.

Myth 4: A2 Milk Cures Lactose Intolerance

Fact: A2 milk does not cure lactose intolerance. However, some people with lactose intolerance report fewer digestive issues with A2 milk, possibly due to the absence of A1 beta-casein.

Myth 5: All Cows Produce A2 Milk

Fact: Not all cows produce A2 milk.

DNA Genotyping is must to confirm whether the milk is A1 or A2.

My Experience with A1 and A2 Milk

Almost a decade ago, I embarked on a project that introduced me to the concept of A2 milk, a topic that was relatively unknown in India at the time. As part of this project, I conducted DNA genotyping on cattle to identify those that produced A2 milk, marking one of the earliest efforts to bring this distinction to the Indian market. This experience was not just about understanding the science; it was also about navigating the complexities of consumer education and market dynamics.

To share more insights from this journey, I gave a AFSTI Powertalk, the video of that has garnered significant attention for its in-depth exploration of the differences between A1 and A2 milk. You can watch the video here.


The FSSAI's Recent Guidelines on A1 and A2 Milk

Fast forward to today, and the A1 vs. A2 milk debate has reached new heights, leading to recent interventions by the FSSAI. The regulatory body had issued an advisory that aimed to regulate the claims made about A1 and A2 milk and milk products. The core of this advisory was to discourage misleading claims regarding the health benefits of A2 milk over A1 milk without sufficient scientific backing.

However, this advisory sparked considerable debate among stakeholders, including dairy producers, consumers, and scientific experts. Many argued that the advisory was premature and lacked clarity, potentially leading to confusion rather than informed consumer choice.

In a significant development, the FSSAI has now withdrawn this advisory. This decision highlights the complexity of the issue and underscores the need for more robust, evidence-based guidelines that can help consumers make informed choices.


Conclusion: A Scientific Perspective

In summary, based on my experience and understanding of the science, I believe that only milk produced by DNA-genotyped A2 cows should be labeled as A2 milk. This ensures that consumers receive the product as advertised, with all its purported benefits.

Additionally, when it comes to ghee, there’s tremendous value in using traditional methods and sourcing milk from desi or grass-fed cows. These practices resonate with consumers like me who appreciate quality and tradition and are willing to pay a premium for such products. As a producer, I also see the market demand for this. However, it's important to clarify that, from a scientific standpoint, ghee—being a clarified butter devoid of protein—cannot technically be classified as A2. This perspective isn't about challenging traditions but rather about promoting a scientifically accurate approach to labeling and marketing.

As the discussion around A1 and A2 milk continues to evolve, it’s crucial that both consumers and producers rely on clear, evidence-based information to make informed decisions.



Literature Reference-

  • Milan, A. M., Shrestha, A., Karlstr?m, H. J., Martinsson, J. A., Nilsson, N. J., Perry, J. K., Day, L., Barnett, M. P. G., & Cameron-Smith, D. Comparison of the impact of bovine milk β-casein variants on digestive comfort in females self-reporting dairy intolerance: A randomized controlled trial. by a2nutrition4professionals
  • Aslam, H., Ruusunen, A., Berk, M., Loughman, A., Rivera, L., Pasco, J. A., & Jacka, F. N. (Year). Unravelled facets of milk-derived opioid peptides: A focus on gut physiology, fractures, and obesity. by a2nutrition4professionals
  • US Dairy. Understanding the science behind A2 milk.
  • Jeong, H., Park, Y. S., & Yoon, S. S. (2024). A2 milk consumption and its health benefits: An update. Food Science and Biotechnology, 33(2), 491-503.
  • Woodford, K. Devil in the Milk: Illness, Health and the Politics of A1 and A2 Milk.

Suraksha Rajagopal

Innovation | Strategy | Product | Data

6 个月

Excellent article, Rita Devi! From what I can see, there is an early indication of gastrointestinal benefits from A2 milk. However, more human studies with larger sample sizes are probably required. Good article that summarises animal and human studies till 2022 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9407547/

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C V Sharma

Freelance Management Consultant

6 个月

Having run a big dairy with own milk collection centres, the first practical question arises that the milk brought by diffrent farmers gets mixed in the chilling tank( cows, buffalo , goat , camel ….). Thus A1 and A2 differentiation in commercial dairy is normally not the practice Assuming the milk of diffrent types of cows can be collected separately ( captive farms having their own cows) , then will also require , processing them separately . To standardise such milk for packing in sachets will require milk powder and butter of same breed of cows . The current commercial dairy system to my knowledge may not be able to cope with such separation on large scales. Thus while the scientific differentiation is interesting but marketing on A1 and A2 basis may end up only in gimmicks as for 99.99% consumers it may be relevant in day today life or for healthcare. In the study of A1 A2 , the one factor which seems to have been neglected(?) about the feed given to such cows. The taste and property of milk changes significantly if cow is fed with Khal, binoley, chane ka atta along with fodders ( Please now I am not a Dairy Technologist nor claim to be expert on dairy products . This just my operational experience)

Ashwini Chitukula

IAM Technical Lead at Wipro Limited

6 个月

Thanks for sharing Rita Devi so informative and cleear to the point.

Sumit Chugh

Food Safety and Regulatory Affairs Professional | Experience in Retail & Manufacturing | Ex Starbucks | Ex YUM!

6 个月

Rita Devi Informative, insightful and Good one.

Mandeep Yadav

Product Development Executive | Master of Technology in Food Technology

6 个月

Good read, very informative...thanks for sharing!!! Just one query - In all cases A1 variant of beta casein will break down into BCM 7?

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