2024 in Review
The Mark Foundation for Cancer Research
Partnering with scientists to accelerate transformation in cancer research
As we close out 2024, we’re proud to reflect on a year of progress in the fight against cancer. Read on to learn about what we’ve achieved and our plans for 2025.
Investing in Early Career Scientists
We presented five remarkable scientists — Edward Chouchani , Bret Freudenthal, Amy Moran, Paul Northcott, PhD , and Aaron Ring — with Emerging Leader Awards?in 2024. These three-year grants, worth a total of $750,000, help early-career researchers pursue their boldest, riskiest ideas. Learn more about their research. ?We’ll announce our 2025 cohort in January —stay tuned!
Making Bold Bets on Promising Reseach
In 2024, we awarded three ASPIRE II Awards to researchers spanning four countries:
This follow-on funding allows awardees to advance work begun through previous ASPIRE grants.
Supporting Tomorrow’s Leaders
We supported the next generation of cancer researchers by awarding nine Momentum Fellowships to talented postdoctoral researchers in four countries to help them accelerate innovative projects. Learn more about their research.
Mihaela Angelova , Thang Do Cong, Pablo Riera Freire, Elizabeth A R Garfinkle, Stephanie Gomez, Júlia Matas Gironella
Driving Multidisciplinary Science
In 2024, we saw exciting progress from our multidisciplinary Centers. At The Mark Foundation Center for Immunotherapy, Immune Signaling, and Radiation at the 美国宾夕法尼亚大学 , team members have made exciting progress in areas including interferon signaling, FLASH radiation, and CAR T-cell therapy. At The Mark Foundation Center for Advanced Genomics and Imaging at the The Johns Hopkins University , researchers continue to advance our understanding of immunotherapeutic approaches to tumor treatment using cutting-edge image analysis tools and techniques.?
Moving the Field Forward
领英推荐
Our grantees have published a remarkable 204 peer-reviewed scientific papers so far in 2024, reflecting the breadth and quality of their work. Each quarter, we share a list of high-impact highlights —view our roundups from the first, second, and third quarters and look out for our fourth-quarter list in January.
Catalyzing New Collaborations
We held two interdisciplinary workshops this year, bringing together global leaders around emerging trends in cancer research. Targeted follow-on funding opportunities are allowing participants to pursue new collaborations launched at the workshops.
In February, we partnered with Takeda to host Precision Targeting of the Tumor Ecosystem, aimed at accelerating the development of novel therapeutics targeting the tumor-TME interface.
No Stone Unturned: Relentless Pursuit of a Cure for Glioblastoma, which we co-hosted last month with The Sontag Foundation , focused on identification, validation, and drug discovery for new targets for this deadly cancer. We’re already looking forward to several exciting workshops planned for 2025!
Tackling Grand Challenges
In March, we committed to funding our third Cancer Grand Challenges team. MATCHMAKERS, which we support alongside Cancer Research UK (CRUK) and the National Cancer Institute (NCI) , is creating tools to predict T cell antigen specificity and unlock more targeted and effective immunotherapies. The other two Mark Foundation-funded teams, SPECIFICANCER and NexTGen, also reported notable scientific progress in 2024.
Partnering to Support High-Impact Research
We regularly partner with other foundations to support individuals and projects at the cutting edge of cancer research. In 2024, those efforts included:
Building Our Network of Experts
This year, we were honored to announce the appointment of four new Mark Foundation advisors: Sarah-Jane Dawson , Johanna Joyce , and Charles Swanton , who joined our Scientific Advisory Committee; and Wendy Young, Ph.D. , who was appointed to the Industry Advisory Committee. Read more about their backgrounds.
Looking Forward to 2025
2025 promises to be a busy and impactful year for The Mark Foundation. In January and February, we’ll announce the recipients of our next Emerging Leader Award, Endeavor Award, and Mark Foundation Center grants and share news about exciting new partnerships. ?Later in the year, we’ll present new ?ASPIRE and Drug Discovery Awards. This April, we will gather in New York City for our Scientific Symposium, where we'll hear updates from our grantees. Throughout the year, we also look forward to convening, learning, and collaborating with many of you at upcoming workshops, conferences, and meetings around the world. We look forward to another year of working together to transform the prevention, diagnosis, and treatment of cancer.
Thank you for your partnership and support and for all that you do to advance cancer research!
Research Professor at ICREA and IRB, co-founder of Nuage Therapeutics
2 个月Thank you for your support !