Pursuing the Promise of Unlimited Platelets

"Universal platelet cells" generated from human induced pluripotent stem cells made their debut last week, courtesy of Advanced Cell Technology (Marlborough, MA). The possibility of producing platelets, the component of blood that stops bleeding, on-demand and circumventing donor rejection could be a game changer for both platelet transfusions and even other tissue transplants.

Universal platelets are free of the infectious agents found in donated versions, allowing companies to skip the mandatory steps of screening donors and testing blood. Platelets also lose their value over time - they cannot be frozen unlike their plasma and red blood cell counterparts that make up blood. They only last at room temperature for up to five days and are more likely to be in short supply. The tantalizing idea of mass produced universal platelets pinged our radar here at WEEKLY, so in this issue we'll examine the science behind the potential of universal platelet technology.

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