20 January 2025
BioTechniques
BioTechniques is an open access journal and online resource, dedicated to the life science research community.
News
CTC-derived organoids establish new tool for investigation of metastasis
The successful cultivation of stable CTC-derived organoids has enabled an investigation into methods of survival and resistance in cancer cells. ?
Are mice reliable models for PD-1 studies?
Mouse PD-1 is significantly weaker than human PD-1, which could have implications for using mice as models in PD-1 studies.
How does Zika virus replicate?
Zika virus hijacks a key protein implicated in brain development for its own replication.
Biotech bi-weekly: 2025 launches with a deluge of industry partnerships
This edition of the biotech bi-weekly sees the year kick off with a flurry of new industry partnerships and C-suite personnel changes alongside the launch of a series of new assays for the investigation of neurodegenerative diseases and a media for the purification of biomolecules.
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New software tool visualizes the inside of 3D images
A new open-source software tool helps see the inside of 3D and 4D images, providing insight into embryonic mouse heart development.
Interviews
Meet the microscopist behind?Amino acids
Every year, we host an image competition showcasing the beauty and intricacy of the life sciences. Last year, the winning image was Amino acids, submitted by José Manuel Martínez López.
José Manuel Martínez López is an electromechanical engineer with a master’s in production engineering. His professional career started in drive systems design and finite element analysis, which has now evolved into a field that intersects with microscopy, science and photography. In 2006, José Manuel joined his sister to run their own company, Química Tech, where he specializes in microscopy.
When people ask José Manuel what he does for a living, he usually answers that he plays with microscopes and teaches others how to get the most out of their microscopes, particularly in the context of life sciences and photography. And we have much to learn!
Read more about José Manuel’s winning image, Amino acids, and his favorite microscopy tips and tricks in this short interview.
Research and resources for open science and publishing integrity
Kelly Cobey is a scientist at the University of Ottawa Heart Institute and an Associate Professor in the School of Epidemiology and Public Health, where she is involved in the Meta Research and Open Science Program. This program conducts research on research and examines the implementation of open science, which involves Kelly exploring science policies or open science practices and auditing their performance to determine if they are successful and being used optimally.
Here, Kelly details the resources and educational tools she and her team have created to address the issues discovered in her work, the challenges of championing open research, and how her dedication to this field has led to her recent award from Sense About Science, the John Maddox Early Career Prize.
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