101 Profitable Products Manufactured By Fermentation Technology

Do you know how antibiotics are manufactured industrially?

Enzymes are multi-purpose products having applications in making cleaning agents, food processing and even as catalyst in product synthesis. But have you ever thought how they’re made industrially?

Do you know about the probiotics and their importance in human health? And are you aware that a wide variety of fermented foods like yogurt are probiotic in nature?

Do you have any idea about the importance of Vitamins in medicines and food products. And do you know how they’re manufactured?

Do you know that important biodegradable polymer polylactic acid is made from Lactic Acid? But how the lactic Acid is manufactured industrially?

Think of the products we’re talking about. No doubt, they’re extremely useful products. But they’re different. Isn't it?

What if I say all of them belong to the same category?

Then the question is: what makes them fall into a common category?

When you get into their manufacturing details, you'll find all of them are manufactured by using fermentation technology. ?That's why we call them fermentation-based products.

Let's get into the details of the above products one by one.

Fermentation based Antibiotics

Do you know about penicillin. It’s one of the most important medical discoveries. In fact, it’s the first antibiotic made industrially. And when you get into the industrial manufacturing process, you’ll find that it’s made by using fermentation technology.

Enzyme Catalysts

Enzymes are nothing but catalyst. And to be exact they’re biocatalysts. Because they get synthesized in the body of the microorganisms and take part in the bioprocesses.

If you get into their industrial manufacturing processes, you’ll find that all of them are made by using fermentation technology.

Probiotics and Fermented Foods

Probiotics are nothing but live microorganisms. They’ve got beneficial effects and keep us healthy.

When you get into the details of fermented foods, you’ll find most of them are made by lactic acid fermentation.

Most of the fermented foods involve live microbes. In that way fermented food is not different from probiotics. Of course, the probiotics contain selected beneficial microorganisms in concentrated form.

So, when you consume sufficient quantity of fermented food, you get the benefits of probiotics.

Vitamins

Vitamins are essential organic compounds, Living organisms need for proper functioning of biological metabolism.

Most of the Vitamins are manufactured industrially using fermentation technology.

Biodegradable Polymer Polylactic Acid

Polylactic acid is the most important biodegradable plastic. It’s used in large variety of consumer products as well as industrial products. And it’s made by condensation polymerization of lactic acid.

When you get into the manufacturing details of lactic acid, you'll find that it’s manufactured by using fermentation technology.

As we’ve mentioned earlier, the products we’re talking about are made by using fermentation technology.

But what do you mean by fermentation technology?

Fermentation Technology

When you get into the details of the manufacturing processes practised in the process industries, you’ll find most of them are based on chemical synthesis.

But chemical synthesis has limitations:

That’s precisely the situation where you use the power of the Fermentation Technology. Fermentation technology can handle complex products. And the process is non-hazardous involving normal process conditions.

Fermentation Technology make use of the power of the microorganisms. In industrial manufacturing, specially developed microorganisms are grown in the fermenters. Of course, for making different products you need different types of microorganisms.

An important point to consider is that during the fermentation process, only the product is made. But the product molecules are still in the fermenter along with the impurities and other undesired molecules.

That’s why proper separation and purification processes become essential to recover and purify the products from the fermented broth.

Let’s come back to the products made by fermentation technology.

You must know about the techno-commercial aspects of the commercially important fermentation technology based products. Isn't it?

Fermentation based Products

The products can be categorized into many categories based on their applications:

• Fermentation based Active Pharmaceutical Ingredients
• Fermentation based Vitamins
• Fermentation based Amino Acids
• Enzymes the Biological Catalysts
• Fermented Foods
• Fermentation based Dietary Supplements and Food Additives
• Other Fermentation based Products

Fermentation based Active Pharmaceutical Ingredients

Have you ever wondered what makes the medicines so effective in curing you from life threatening diseases?

The medicines are formulation products. Here the actual job of fighting with the diseases is done by the active molecules present in the medicines. And that’s why we call them Active Pharmaceutical Ingredients.

If you talk about the active pharmaceutical ingredient molecules, they’re of two types:?

Small Molecules

Active pharmaceutical ingredients coming under the small molecule category are low molecular weight compounds. If you study the active pharmaceutical ingredients used in the medications, you’ll find the major percentage to be small molecules.

Large Molecules

Active pharmaceutical ingredients coming under the large molecule category are structurally very complex and have high molecular weights. Of course, the industrial manufacturing involves specialized fermentation technology.

However, we shall focus on the active pharmaceutical ingredients in small molecule category in this article.

These active molecules are industrially manufactured by employing two processes. The first is chemical synthesis and the other is fermentation technology.

But we shall focus on fermentation technology.

The fermentation based active pharmaceutical ingredients can be classified into six categories:

• Fermentation based Antibacterial Molecules
• Fermentation based Antifungal Molecules
• Fermentation based Anticancer Molecules
• Fermentation based Cholesterol Lowering Molecules
• Fermentation based Immunosuppressants
• Other Fermentation based Active Molecules

Fermentation based Antibacterial Molecules

Antibiotics are active pharmaceutical ingredients effective against the diseases caused by bacterial pathogens. There are many fermentation based antibacterial molecules manufactured industrially.

Let’s talk about the products made by industrial fermentation.

??????? 1.?????? Penicillin GK

Penicillin G Potassium is a Beta Lactam antibiotic made by using fermentation technology. In fact, it’s employed as key starting material to make many semi-synthetic Penicillins and Cephalosporins.

??????? 2.?????? Clavulanic Acid

Clavulanic Acid is a Beta Lactam antibiotic made by using fermentation technology. In fact, it’s not effective as an antibiotic. But when it’s combined with penicillin-group antibiotics, it can make them effective against the bacteria that secrete beta lactamase enzyme which inactivates the penicillins.

??????? 3.?????? Cephalosporin – C

Cephalosporin – C is a Beta Lactam antibiotic made by using fermentation technology. It’s employed as key starting material to make many important semi-synthetic Cephalosporins.

??????? 4.?????? Erythromycin Thiocyanate

Erythromycin Thiocyanate is a Macrolide antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications. It’s also employed as key starting material to make important semi-synthetic Macrolide antibiotics.

??????? 5.?????? Gentamicin

Gentamicin is an Aminoglycoside antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

??????? 6.?????? Streptomycin

Streptomycin is an Aminoglycoside antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

??????? 7.?????? Neomycin

Neomycin is an Aminoglycoside antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

??????? 8.?????? Kanamycin

Kanamycin is a Aminoglycoside antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

??????? 9.?????? Spectinomycin

Spectinomycin is an Aminocyclitol antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 10.????? Vancomycin

Vancomycin is a Glycopeptide antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 11.????? Tobramycin

Tobramycin is a Aminoglycoside antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 12.????? Tetracycline

Tetracycline is a brad spectrum antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 13.????? Oxytetracycline

Oxytetracycline is a broad spectrum antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 14.????? ?Rifamycin

Rifamycin is an important antibiotic made by using fermentation technology. It is employed as key starting material to make important semi-synthetic Rifamycin group of antibiotics.

????? 15.????? ?Mupirocin

Mupirocin is an important antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 16.????? Fusidic Acid

Fusidic Acid is an important antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 17.????? Pleuoromutilin

Pleuoromutilin is an important antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 18.????? ?Bacitracin

Bacitracin is a polypeptide antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 19.????? Teicoplanin

Teicoplanin is a Glycopeptide antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 20.????? Polymyxin B

Polymyxin B is a Polypeptide antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 21.????? Daptomycin

Daptomycin is a Lipopeptide antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 22.????? Fidaxomicin

Fidaxomicin is a Macrocyclic antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

????? 23.????? Chloramphenicol

Chloramphenicol is a broad spectrum antibiotic made by using fermentation technology. It is used as active pharmaceutical ingredient in antibacterial medications.

Fermentation based Antifungal Molecules

Antifungal Molecules are active pharmaceutical ingredients effective against the diseases caused by fungal pathogens. There are many fermentation based antifungal molecules manufactured industrially.

Let’s talk about the products made by industrial fermentation.

????? 24.????? Amphotericin B

Amphotericin B is a Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications. It’s used for serious fungal infections.

????? 25.????? Griseofulvin

Griseofulvin is an Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications.

????? 26.????? Caspofungin

Caspofungin is an Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications.

????? 27.????? Nystatin

Nystatin is an Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications.

????? 28.????? Natamycin

Natamycin is an Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications.

????? 29.????? Hamycin

Hamycin is an Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications.

????? 30.????? Anidulafungin

Anidulafungin is an Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications.

????? 31.????? Micafungin

Micafungin is an Antifungal molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antifungal medications.

Fermentation based Anticancer Molecules

Anticancer Molecules are active pharmaceutical ingredients effective against the cancer. There are many fermentation based anticancer molecules manufactured industrially.

Let’s talk about the molecules for the treatment of cancer made by industrial fermentation.

????? 32.????? ?Romedepsin

Romedepsin is an anticancer molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in anticancer medications.

????? 33.????? ?Mitomycin

Mitomycin is an anticancer molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in anticancer medications.

????? 34.????? Dactinomycin

Dactinomycin is an anticancer molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in anticancer medications.

????? 35.????? Midostaurin

Midostaurin is an anticancer molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in anticancer medications.

????? 36.????? Daunorubicin

Daunorubicin is an anticancer molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in anticancer medications.

????? 37.????? Doxorubicin

Doxorubicin is an anticancer molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in anticancer medications.

Fermentation based Cholesterol Lowering Molecules

Cholesterol lowering molecules are active pharmaceutical ingredients are effective in decreasing the cholesterol level in the blood. That’s how they help in avoiding blocked arteries and treat cardiovascular diseases. There are some fermentation based cholesterol lowering molecules manufactured industrially.

Let’s talk about the molecules made by industrial fermentation.

????? 38.????? Lovastatin

Lovastatin is a cholesterol lowering molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in cardiovascular medications.

????? 39.????? Mevastatin (Compactin)

Mevastatin also call Compactin is a cholesterol lowering molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in cardiovascular medications.

????? 40.????? Pravastatin

Pravastatin is a cholesterol lowering molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in cardiovascular medications.

Fermentation based Immunosuppressants

Immunosuppressants molecules are active pharmaceutical ingredients are effective in reducing body’s immune response. That’s how they help in treating some diseases. There are some fermentation based immunosuppressant molecules manufactured industrially.

Let’s talk about the molecules made by industrial fermentation.

????? 41.????? Sirolimus

Sirolimus is an immunosuppressant molecule made by using fermentation technology. It is also used to make some semi synthetic immunosuppressant molecules.

????? 42.????? Tacrolimus

Tacrolimus is an immunosuppressant molecule made by using fermentation technology.

????? 43.????? Cyclosporin A

Sirolimus is an immunosuppressant molecule made by using fermentation technology.

????? 44.????? Mycophenolic Acid

Mycophenolic Acid ad it’s salts are immunosuppressant molecules made by using fermentation technology.

Other Fermentation based Active Molecules

There are many other fermentation based Active Pharmaceutical Ingredients molecules and advanced intermediates manufactured industrially. They’re used for the treatment of different diseases and medical conditions.

Let’s talk about the molecules made by industrial fermentation.

????? 45.????? Acarbose

Acarbose is an antidiabetic molecule made by using fermentation technology. It is used as active pharmaceutical ingredient in antidiabetic medications.

????? 46.????? Miglitol

Miglitol is a semisynthetic antidiabetic molecule. It’s made from 1-deoxynojirimycin which is made by using fermentation technology. Miglitol is used as active pharmaceutical ingredient in antidiabetic medications.

????? 47.????? Voglibose

Voglibose is a semisynthetic antidiabetic molecule. It’s made by using fermentation technology. Voglibose is used as active pharmaceutical ingredient in antidiabetic medications.

????? 48.????? Artemisinin

Artemisinin is an antimalarial molecule made by using fermentation technology. Artemisinin along with it’s semisynthetic derivatives are used as active pharmaceutical ingredient in antimalarial medications.

????? 49.????? Deferoxamine

Deferoxamine is used to treat acute iron poisoning. Deferoxamine is used as active pharmaceutical ingredient in making the medications which binds iron and aluminium. It is made by using fermentation technology.

????? 50.????? Ivermectin

Ivermectin is an antiparasitic molecule made by using fermentation technology. Ivermectin is used as active pharmaceutical ingredient in antiparasitic medications.

Fermentation based Vitamins

As we’ve discussed earlier, vitamins are essential organic compounds. Because sufficient vitamins are not synthesized in the body, food fulfils the vitamin requirements.

But vitamin deficiency results in various diseases. That’s why it becomes necessary to consume food fortified with vitamins and vitamin supplements.

When get into the details on how vitamins are made, you’ll find many of the Vitamins are manufactured industrially using fermentation technology. Of course, chemical synthesis is used industrially to make many of the vitamins. But because of vitamin usage in food and pharmaceutical applications, fermentation technology is preferred.

Let’s talk about the molecules made by industrial fermentation.

????? 51.????? Vitamin A

Vitamin A is an essential fat-soluble vitamin. It is essential for biological functions like embryo development and growth, maintenance of the immune system, and vision. Though it’s made by chemical synthesis, the recent manufacturing process is based on fermentation technology.

????? 52.????? Vitamin B1 (Thiamine)

Vitamin A is an essential water-soluble vitamin. It is essential for biological functions like energy production and nervous system. Industrial Manufacturing of Thiamine is based on both chemical synthesis and fermentation technology.

????? 53.????? Vitamin B2 (Riboflavin)

Vitamin B2 is an essential water-soluble vitamin. It is essential for biological functions like metabolism, skin, hair and immune system. Industrial Manufacturing of Riboflavin is based on both chemical synthesis and fermentation technology.

????? 54.????? Vitamin B5 (Pantothenic Acid)

Vitamin B5 is an essential water-soluble vitamin. It is essential for biological functions like metabolism and producing red blood cells. Industrial Manufacturing of Pantothenic Acid is based on both chemical synthesis and fermentation technology.

????? 55.????? Vitamin B12 (Cobalamins)

Vitamin B12 is an essential water-soluble vitamin. It is essential for biological functions related to nervous system, brane function and producing red blood cells. Industrial Manufacturing of Cobalamins is based on fermentation technology.

????? 56.????? Vitamin C (Ascorbic Acid)

Vitamin C is an essential water-soluble vitamin. It is essential for repair of tissue, formation of collagen and immune system functioning. Industrial Manufacturing of Ascorbic Acid is based on semi-synthetic process - the key intermediate is manufactured by fermentation technology while the final step is based on chemical synthesis.

????? 57.????? Vitamin D2 (Ergocalciferol)

Vitamin D2 is an essential fat-soluble vitamin. It is essential for increasing Intestinal absorption of calcium, magnesium, and phosphate in the body. Industrial Manufacturing of Ergocalciferol is based on semi-synthetic process - ergosterol is manufactured by fermentation technology while the final step is based on ultraviolet irradiation.

????? 58.????? Vitamin K2 (Menaquinone)

Vitamin D2 is an essential fat-soluble vitamin. It is essential for heart and bone health. Industrial Manufacturing of Menaquinone is based on fermentation technology.

Fermentation based Amino Acids

Amino acids are building blocks of proteins. The amino acid molecules are the monomers. In fact, protein molecules are the polymers of amino acids. The condensation polymerisation reaction is used to make the polymers. ?With short polymer chains peptide molecules are formed while longer chains result in polypeptides or proteins.

Some of the amino acids are not synthesized in the body, food fulfils the amino acid requirements. Amino acids are required to make proteins and peptides in the body. Additionally amino acids are needed for many biosynthetic pathways.

When get into the details on how amino acids are made, you’ll find many of the molecules are manufactured industrially using fermentation technology.

Of course, chemical synthesis is used industrially to make many of the amino acids. But natural processes like fermentation technology is preferred. because amino acids are used in food and pharmaceutical products.

Let’s talk about the molecules made by industrial fermentation.

????? 59.????? Glutamic Acid

Glutamic acid is an important amino acid. Most of it is used as food additive to enhance the flavor. Industrial Manufacturing of Pantothenic Acid is based on fermentation technology.

????? 60.????? Lysine

Lysine is an important amino acid. Most of it is used as food supplement and animal feed. Industrial Manufacturing of Lysine is based on fermentation technology.

????? 61.????? L-Phenylalanine

L-Phenylalanine is an important amino acid. Most of it is used as food supplement and in manufacturing artificial sweetener - Aspartame. Industrial Manufacturing of L-Phenylalanine is based on fermentation technology.

????? 62.????? L-Tryptophan

L-Tryptophan is an important amino acid. Most of it is used in pharmaceutical industry. Industrial Manufacturing of L-Tryptophan is based on both chemical synthesis and fermentation technology.

????? 63.????? L-Mithionine

L-Methionine is an important amino acid. Most of it is used as food supplement and animal feed. Industrial Manufacturing of L-Methionine is based on both chemical synthesis and fermentation technology.

????? 64.????? L-Valine

L-Valine is an important amino acid. Most of it is used as food supplement and animal feed. It has also got industrial usage as an intermediate. Industrial Manufacturing of L-Methionine is based on both chemical synthesis and fermentation technology.

????? 65.????? L-Threonine

L-Threonine is an important amino acid. Most of it is used as food supplement and animal feed. Industrial Manufacturing of L-Threonine is based on fermentation technology.

????? 66.????? Isoleucine

Isoleucine is an important amino acid. Most of it is used as food supplement and animal feed. It has also got industrial usage as an intermediate. Industrial Manufacturing of Isoleucine is based on both chemical synthesis and fermentation technology.

Enzymes the Biological Catalysts

Hundreds of biochemical reactions are taking place every moment in the body of the living organisms. It’s because of the Enzymes. Because the enzymes are biochemical catalysts. That’s why biochemical reactions are perfect.

Commercial enzymes utilize this advantage. If you talk about their usage, enzymes are multi-utility products. Additionally, one very important application of enzyme is in organic synthesis. Many value-added products are synthesized by using enzymes as catalysts.

But how to make the enzymes for their commercial use?

When you get into their industrial manufacturing processes, you’ll find that most of them are made by using fermentation technology. Because they get synthesized in the body of the microorganisms in high yield.

Let’s talk about the enzymes made by industrial fermentation.

????? 67.????? Alfa Amylase

Alfa Amylase is an important enzyme. It is used to hydrolyse starchy substances. It finds use in food, textile, paper, detergent and pharmaceutical industries. Industrial Manufacturing of Alfa Amylase is based on fermentation technology.

????? 68.????? Lipase

Lipase is an important enzyme. It is used to hydrolyse oils and fats. It finds use in food, dairy, detergent and pharmaceutical industries. Industrial Manufacturing of Alfa Amylase is based on fermentation technology.

????? 69.????? Serratiopeptidase

Serratiopeptidase is an important enzyme. It is used to hydrolyse non-living proteins inside the body. It finds use in making medications for inflammation and pain. Industrial Manufacturing of Serratiopeptidase is based on fermentation technology.

????? 70.????? Glucose Isomerase

Glucose Isomerase is an important enzyme. It is used to convert glucose to fructose. It finds use in manufacturing high fructose corn syrup. Industrial Manufacturing of Glucose Isomerase is based on fermentation technology.

????? 71.????? Cellulase

Cellulase is an important enzyme. It is used to hydrolyse cellulose. It finds use in food, textile and biomass refining. Industrial Manufacturing of Cellulase is based on fermentation technology.

????? 72.????? Protease

Protease is an important enzyme. It is used to hydrolyse proteinaceous substances. It finds use in food, detergent and pharmaceutical industries. Industrial Manufacturing of Protease is based on fermentation technology.

????? 73.????? Streptokinase

Streptokinase is an important enzyme. It is used to dissolve blood clots formed in the blood vessels. It finds use in making cardiovascular medications. Industrial Manufacturing of Streptokinase is based on fermentation technology.

????? 74.????? Nitrile Hydratase

Nitrile Hydratase is an important enzyme. It is used to catalyses conversion of Nitriles to the corresponding Amides. It finds use in manufacturing commercially important products Acrylamide and Nicotinamide. Industrial Manufacturing of Glucose Isomerase is based on fermentation technology.

????? 75.????? Mannanase

Mannanase is an important enzyme. It is used to hydrolyse mannan a polysaccharide. It finds use in food, paper and pulp industries and in making detergents. Industrial Manufacturing of Mannanase is based on fermentation technology.

????? 76.????? Pectinase

Pectinase is an important enzyme. It is used to hydrolyse plant cell wall made of Pectin a gelatinous polysaccharide. It finds use in food industry especially in fruit juice extraction and clarification. Industrial Manufacturing of Pectinase is based on fermentation technology.

????? 77.????? Lactase

Lactase is an important enzyme. It is used to hydrolyse milk sugar lactose. It finds use in food industry to make lactose free dairy products. And Lactase supplement is used to treat lactose intolerance. Industrial Manufacturing of Lactase is based on fermentation technology.

????? 78.????? Chemosyn

Chemosyn is an important enzyme. It is used in dairy industry in modern cheese manufacturing. Industrial Manufacturing of Chemosyn is based on fermentation technology.

????? 79.????? Invertase

Invertase is an important enzyme. It is used to make Inverted Sugar Syrup which is a very important product for food and beverage industry. Industrial Manufacturing of Invertase is based on fermentation technology.

????? 80.????? Xylanase

Xylanase is an important enzyme. It is used to hydrolyse polysaccharide - xylan. It finds use in food, paper and biofuel industry. Industrial Manufacturing of Pectinase is based on fermentation technology.

Fermented Foods

Fermented foods involve natural fermentation where natural microorganisms do the process. Most of the fermented foods involve two types of fermentation. One is alcohol fermentation and the other is lactic acid fermentation. ?

The fermentation not only preserves the food but also enhances its flavor and nutritional qualities.

In fact, it increases the availability of beneficial probiotics—live bacteria that support gut health. And these food products are rich in vitamins, minerals, enzymes and other nutritional ingredients. Thet’s why they’re great for digestion and boost the immune system.

Today consumers are showing increasing interest in healthy, natural foods. That’s why the fermented food products are in high demand.

When you get into the manufacturing processes of fermented foods, you’ll find enough opportunities to enhance the fermentation technology. That’s how you can make available high quality fermented foods at affordable prices and meet the market demand.

Let’s talk about the commercially important lactic acid fermented food products:

????? 81.????? Yogurt or Curd

Yogurt or curd is an important dairy product. It is made by lactic acid fermentation of dairy milk cream. Commercial products are pasteurized to enhance their shelf life.

????? 82.????? Cultured Butter

Cultured Butter is an important dairy product. It is made by lactic acid fermentation of dairy milk cream. In this process, another important fermented food product – Butter Milk is also made.

????? 83.????? Cheese and Paneer

Cheese is an important dairy product. It is made by lactic acid fermentation of dairy milk. There are many types of cheese available based on the process and the raw materials used. Paneer (cottage cheese) is also made similarly from dairy milk.

????? 84.????? Fermented Pickle

Different types of fermented pickles are made. They involve lactic acid fermentation of vegetables. Sauerkraut is made by lactic acid fermentation of cabbage. And Kimchi is made from cabbage or radish. Miso and Tempeh are made from soyabean.

Products like alcoholic beverages ?and vinegar are made by alcoholic fermentation. Let’s talk about them:

????? 85.????? Beer

It is an important alcoholic beverage. It’s made by alcoholic fermentation of malted barley. Most of the beer made is brewed with hops for flavor. Commercial products are carbonated in addition to natural carbonation.

????? 86.????? Wine

It is an important alcoholic beverage. It’s made by alcoholic fermentation of fruits. Most of the wine is made from grapes. But other fruits can be used.

????? 87.????? Distilled Alcoholic Beverages

They’re important alcoholic beverages. They’re made by alcoholic fermentation of fruits, grains, vegetables and sugar. Once the fermentation process is over the mass is distilled to get distilled alcoholic beverages.

????? 88.????? Natural Vinegar

They’re made by alcoholic fermentation of fruits, grains, and sugar followed by acetic acid fermentation. Alcoholic beverages can be used to make vinegar by fermentation.

Fermentation based Dietary Supplements and Food Additives

In order to stay healthy and fit you need proper nutrition. But due to various reasons there may be gaps in your nutrition.

That’s where dietary supplements come into the picture.

Dietary Supplements

They help fill the nutritional gaps in your diet to ensure that you get the essential vitamins, minerals, and other nutrients.

Because dietary supplements provide essential nutrients that may be missing or insufficient in your regular diet. They are used to support overall health, enhance immune function, improve physical performance, and manage specific health conditions.

When it comes to nutrition, you can’t ignore food processing. Food processing is essential to preserve food products and make them available to all at affordable prices.

But modern food processing needs different types of food additives for efficient operation.

Food Additives

When you get into the details of processed food manufacturing, you’ll find the usage of food additives is necessary. They are added to food products during processing to enhance their flavour, appearance, texture and to achieve extended shelf life.

When get into the details on how the dietary supplements and the food additives are made, you’ll find some of them are manufactured industrially using fermentation technology.

Of course, chemical synthesis and extraction from the natural sources are used industrially to make many of these products. But natural processes like fermentation technology and extraction from the natural sources are preferred. because of their usage in food industry.

Let’s talk about the products made by industrial fermentation.

????? 89.????? Astaxanthin

Astaxanthin is an important Dietary Supplement. It’s made by fermentation technology using algae. Algae grow in the presence of light to make astaxanthin.

????? 90.????? Spirulina Algae

Spirulina Algae is an important Dietary Supplement. It’s made by fermentation technology using algae. Algae is cultivated in the presence of light.

????? 91.????? Omega 3 Fatty Acids

Omega 3 fatty acids are important dietary supplement. It’s having powerful nutritional properties. It’s made by extracting from natural sources. But recently fermentation technology has been developed to make the product.

????? 92.????? Baker’s Yeast

Baker’s Yeast is an important food additive. It’s used in baking industry in making bread and other bakery products. It’s made by using fermentation technology.

????? 93.????? Erythritol

Erythritol is an important sugar substitute and flavor enhancer. Chemically it’s a sugar alcohol. It’s used in food industry as food additive. It’s made by using fermentation technology.

Other Fermentation based Products

If you get into the details on how the commercially important products are made, you’ll find some of them are manufactured industrially using fermentation technology.

They may be agricultural active ingredients, organic chemicals, fine chemicals or monomers for polymerization.

Let’s talk about the products made by industrial fermentation.

????? 94.????? Spinosad

Spinosad is an important agrochemical. It is the active ingredient in agrochemical formulations used in controlling insect pests. Industrial Manufacturing of Isoleucine is based on fermentation technology.

????? 95.????? Gibberellic Acid

Gibberellic Acid is an important agricultural active ingredient. It’s used in agriculture as plant growth regulator. It’s made by using fermentation technology.

????? 96.????? Biofertilizer

Biofertilizer is an important agricultural active formulation. In fact, its a formulation of living microorganisms which act as fertilizer. It’s made by using fermentation technology.

????? 97.????? Biopesticide

Biopesticide is an important agricultural active formulation. In fact, its a formulation of living microorganisms effective in controlling insects and pests. It’s made by using fermentation technology.

????? 98.????? Citric Acid

Citric Acid is an important organic acid. It’s a high volume multi-utility product having applications in food, personal care, pharmaceutical and speciality chemical industry. It’s made by using fermentation technology.

????? 99.????? Gluconic Acid

Gluconic Acid is an important organic acid. It’s a multi-utility product having applications in food, textile, personal care, pharmaceutical and speciality chemical industry. It’s made by using fermentation technology.

??? 100.??? Kojic Acid

Kojic Acid is an important organic acid. It’s a multi-utility product having applications in food, cosmetics and pharmaceutical industry. Industrial manufacturing is based on Chemical synthesis and fermentation technology.

??? 101.??? Itaconic Acid

Itaconic Acid is an important organic acid. It’s a multi-utility product having applications in paints & coating, polymer, pharmaceutical and speciality chemical industry. It’s made by using fermentation technology.

??? 102.??? Anhydrous Ethanol

Ethanol is an important organic chemical. It’s a multi-utility product having applications as solvent, chemical feedstock. Today its major use is in fuel blending. It’s made by using fermentation technology.

??? 103.??? Lactic Acid

Lactic acid is an important organic chemical. It’s a multi-utility product having applications in food, cosmetics and pharmaceutical industry. Today its major use is as monomer in making biodegradable polymer – polylactic acid. It’s made by using fermentation technology.

??? 104.??? PolyHydroxyAlkanoate

Polyhydroxyalkanoate is an important biodegradable, non-toxic polymer. It’s a used in controlled release medicines, medical implants and orthopedic devices It’s made by using fermentation technology.

Let’s Conclude

Fermentation technology is a boon to the process industry.

Because fermentation technology can handle complex products. And the process is non-hazardous involving normal process conditions. And above all it uses renewable bio-based raw materials like sugarcane juice, starchy feed stock and lignocellulosic wastes.

Fermentation Technology make use of the power of the microorganisms. It’s a environment friendly manufacturing process and a sustainable alternative to chemical synthesis.

In order to be successful in the manufacturing business, you must know about the techno-commercial aspects of the commercially important fermentation technology based products.

The products can be categorized into many categories based on their applications:

• Fermentation based Active Pharmaceutical Ingredients
• Fermentation based Vitamins
• Fermentation based Amino Acids
• Enzymes the Biological Catalysts
• Fermented Foods
• Fermentation based Dietary Supplements and Food Additives
• Other Fermentation based Products

Fermentation based Active Pharmaceutical Ingredients

The fermentation based active pharmaceutical ingredients can be classified into six categories:

• Fermentation based Antibacterial Molecules
• Fermentation based Antifungal Molecules
• Fermentation based Anticancer Molecules
• Fermentation based Cholesterol Lowering Molecules
• Fermentation based Immunosuppressants
• Other Fermentation based Active Molecules

There’re many commercially important fermentation based products you can manufacture profitably and sustainably.

Here, we’ve covered more than 101 products in order to introduce you to the world of commercially important fermentation-based products. If you notice, we’ve not mentioned some fermentation-based products in the list. In fact, those products may be suitable for you.

Because when you study the products, you can evaluate them in a targeted way against important techno-commercial basis. The aim is to match the products with the resources available to you. Then only you can add value to your manufacturing business.

Let’s join hands in using innovations in manufacturing fermentation-based products and developing them further to make your Manufacturing Business Profitable and Sustainable.

I'm curious to hear your thoughts on this exciting topic. Share your insights in the comments below!

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