Microglia Function
Under some circumstances, such as programmed cell death occurs or CNS is injured, microglia will work as brain macrophages to clear tissue debris, damaged cells, or microbes. Besides, microglial cells are also scavenging the CNS for plaques, damaged or unnecessary neurons and synapses, and infectious agents constantly, the processes of which are potentially dangerous. Therefore, microglia are extremely sensitive to pathological changes.