HaCaT cell line is the immortalized human keratinocyte cell line that transformed from adult skin.
HaCaT Culture properties
HaCaT cell culture can also form stratified epidermal structure. However, the form can transmit between a differentiated and a basal state depending on Ca2+ concentration changes in the medium. Result of cytokine production suggests that HaCaT keratinocytes maintain 80% confluent similar to normal keratinocytes in low Ca2+ concentration media.
Why Choose HaCaT from AcceGen?
AcceGen HaCaT cells maintain the normal keratinocyte morphogenesis, major surface marker and functions. The circumstances of stimulation promote HaCaT cells to differentiate and express specific markers such as keratin(K)14 and inyolucrin.