BV-2

For research use only BV-2 Cells Application and example model In the central nervous systems (CNS), microglial cells are resident macrophages. BV-2 shares properties with body macrophages with respect to the antigen profile, their phagocytic capacity and antimicrobial activity. Like other microglia, BV-2 can be activated to release pro-inflammatory cytokines by oxidative stress or inflammatory factors. Such stimulus possibly triggers neurodegenerative disorder.