VIVALDI H2020 project的动态

It was a pleasure to meet and discuss with Prof. C. Oliver Kappe. Your extensive contributions to the field of flow chemistry and deep understanding of the technology are truly impressive. #flownetics #flowchemistry #achema2024 #sustainability #cleanchemistry #innovation #machinelearning #flowreactor

Continuous Flow Hydroxylation of Benzene to Phenol in a Photocatalytic Millistructured Flat-Plate Reactor "Phenol can be produced from benzene via #photocatalytic hydroxylation. A #continuous_flow_flat_plate_reactor emerges as a promising option, as it allows for a large irradiation window and a short photon penetration depth. In this work, TiO2 (Degussa P25) was applied as a photocatalyst. The use of smectite clays and a 3D-printed casting template was the key to the uniform immobilization of photocatalysts over the glass window surface. Acetonitrile was selected as a carrier solvent for benzene since the #fluid_dynamics exhibited an efficient mixing with the aqueous H2O2 flow solution. Furthermore, the response surface methodology was employed to examine the effects of residence time, temperature, and light power. Our flat-plate reactor produced a high photocatalytic space-time yield of 1.2 × 10–11 mol/W s, which is about 1–2 orders of magnitude higher than the reported batch setups. The transport phenomena equation was also formulated to elucidate the kinetics of the photocatalytic reaction, giving the adsorption constant and the intrinsic kinetic constant to be 0.0535 m3/mol and 8.21 × 10–6 mol/(m2·s), respectively." Chetsada Khositanon, Waichaya Sirimongkhol, Nopphon Weeranoppanant, Department of Chemical Engineering, Faculty of Engineering, Burapha University, Chonburi, Thailand; Taya Saothayanun, Makoto Ogawa, Sareeya Bureekaew, School of Energy Science and Engineering (ESE), Vidyasirimedhi Institute of Science and Technology (VISTEC), Rayong, Thailand; Somboon Sukpancharoen, Department of Agricultural Engineering, Faculty of Engineering, Khon Kaen University, Khon Kaen, Thailand. https://lnkd.in/eitQpEzq

Check out MIOCA's article in the latest issue of @officialMichBio's BioMatters magazine.

My very last paper as a researcher in Duhme-Klair's group has just been accepted for publication in ACS Catalysis! Of course I had to design a cover and a graphical abstract for it :) Here are the highlights, but be sure to read the whole thing, it's open access! ? It focuses on the creation of redox-reversible artificial metalloenzymes, specifically transfer hydrogenases, by combining synthetic metal complexes with protein scaffolds. ? We used a catch-and-release strategy to immobilise polyhistidine-tagged ArMs on Ni@S resin, allowing reversible anchoring of the catalytic cofactor. This approach allows recycling and replacement of deactivated components. ? Immobilised ArMs, particularly those with thermophilic bacterial protein scaffolds, have shown improved stability, recyclability and ability to be reloaded with fresh catalytic cofactor. This approach supports multiple reaction cycles, contributing to commercial viability and environmental sustainability. Co-Authors: Alex Henrique Miller, Elena Blagova, Rosalind Booth and Keith Wilson #SciArt???#Research???#Chemistry

My very last paper as a researcher in Duhme-Klair's group has just been accepted for publication in ACS Catalysis! Of course I had to design a cover for it :) Here are the highlights, but be sure to read the whole thing, it's open access! ? It focuses on the creation of redox-reversible artificial metalloenzymes, specifically transfer hydrogenases, by combining synthetic metal complexes with protein scaffolds. ? We used a catch-and-release strategy to immobilise polyhistidine-tagged ArMs on Ni@S resin, allowing reversible anchoring of the catalytic cofactor. This approach allows recycling and replacement of deactivated components. ? Immobilised ArMs, particularly those with thermophilic bacterial protein scaffolds, have shown improved stability, recyclability and ability to be reloaded with fresh catalytic cofactor. This approach supports multiple reaction cycles, contributing to commercial viability and environmental sustainability. Co-Authors: Alex Henrique Miller, Elena Blagova, Rosalind Booth and Keith Wilson #SciArt???#Research???#Chemistry

?? #ACHEMA starts tomorrow! We can be found at the joint stand of the Fraunhofer Chemistry Alliance in Hall 6.0 | D49 and look forward to discussions about ? - the electrification of chemical processes - energy- and resource-efficient chemical reactions in ohmic reactors - the recycling of plastics - sustainable geosynthetics - green metrics ? In addition, our researchers will provide insights into their work in various presentations: ? June 10 - Dr. Alexander Hofmann: Synergies between mechanical and chemical recycling of plastics – consideration of economic, ecological and social aspects ? June 11 - Prof. Dr.-Ing. G?rge Deerberg: #Carbon2Chem??– a key building block for climate protection - Marc Greuel: Electrification methods for industry – A possible way for heterogeneous catalysis? Ethanol to butadiene as a case study - Dr.-Ing. Tim Nitsche: Non-thermal plasma technologies for chemical conversions: Scale-up of a novel plasmachemical oxygen removal process ? June 13 - Jonas Wolf: Electroplated electrodes allow for continuous and mass-efficient electroorganic hydrogenation - Thomas Fehn: INNOTEER – Innovative technology for the recycling of tar-containing road construction ? #CircularEconomy #CarbonManagement #GreenChemistry ACHEMA 2024

?? After five years of dedicated #research and collaboration, the project CLASSY has come to a successful closure. This ambitious project, funded by the #EuropeanUnion, aimed to explore the potential of chemical systems and networks in various fields of research. We at accelopment have been part of this dedicated consortium under the coordination of Prof. Andrés de la Escosura from Universidad Autónoma de Madrid, Spain. ? The project made significant advances in the understanding of the self-organisation of multi-component synthetic systems, leading to groundbreaking research on the efficiency of enzymes in the presence of peptide catalysts. The success of #CLASSY has also sparked new initiatives and partnerships - several new #HorizonEurope funded projects, such as CORENET, DarChemDN, and MiniLife. ?? The final Scientific Symposium event, held virtually in March 2024, was a major milestone for the project. Attended by over 50 participants from 42 organisations, the event showcased the latest findings and developments from CLASSY. It also served as a platform to disseminate the outcomes of the project to a wider audience and foster collaborations with external experts in #catalysis and compartmentalisation strategies in systems #chemistry. Discover more about CLASSY and its results ?? https://lnkd.in/dpfUAUue

Life finds a way – The biological principle of self-healing is a promising way to reduce the burden on SME managers involved in many processes. The "Interactive Situation Awareness Monitor" is used, among other things, to identify changes at an early stage. Annika Lange and her team at Fraunhofer IPK are extending the "Interactive Situation Awareness Monitor" by applying principles from biology and nature. Environmental data is analysed based on the frequency of mentions to identify emerging trend topics. In this way, changes can be detected early and appropriate measures can be taken. Find out more about project BioFusion 4.0 on the project website. The BioFusion 4.0 partners are Fraunhofer IPK, Technische Universit?t Berlin, Mercedes-Benz AG, Bral Reststoff-Bearbeitungs GmbH, budatec GmbH, ARBURG GmbH + Co KG, COLLIN Lab & Pilot Solutions, CONTACT Software, GreenDelta GmbH, KleRo GmbH Roboterautomation, ModuleWorks, 5thIndustry, Werner-von-Siemens Centre for Industry and Science e.V. #BioFusion #BiologicalTransformation #Industry40 #Production #ProductionSystems

#ICIQSeminar | ??Thank you Prof. Rebecca Melen from Cardiff University / Prifysgol Caerdydd for delivering a seminar about the donor-acceptor ability of frustrated Lewis pairs. ?? Single electron transfer from a Lewis base donor to a Lewis acid acceptor can produce a frustrated radical species. This depends on both the substrate and energy required to promote a frustrated Lewis pairs into a frustrated radical pair. ??Prof. Melen discussed using borane Lewis acids in catalytic cyclization reactions. When paired with PMes?, they form radical frustrated pairs, enabling C–C and C–S bond formation. This opens innovative pathways for chemical synthesis. ??New applications of borane Lewis acids in diazo activation were highlighted by Prof. Melen. These methods replace transition metals in a range of catalytic transformations, offering sustainable and efficient alternatives. ?? Also thanks to our seminar sponsor BASF ICERCA - Centres de Recerca de Catalunya | Barcelona Institute of Science and Technology (BIST) | SOMM Alliance

Interesting report that highlights some of the key challenges we currently experience in working with and communicating biotechnology across different geographies and regulatory frameworks. At the core is a need for consistency in data recording and measurement, particularly across development scales and consistent use language and terminology from region to region (and sector to sector). The findings echo a lot of what we set out to achieve at ōGI Bio with our tools for strain and process development - more consistency, reproducibility and relevance right from the start of the development process.