University of Chicago Department of Chemistry

University of Chicago Department of Chemistry grad student Sam Marsden is working to create new, recyclable plastics that combine the strength of polyethylene with the recyclability of PET. Be sure to read the insightful piece from Pritzker School of Molecular Engineering at the University of Chicago about how his research aims to establish a more sustainable future. https://lnkd.in/geNAPRDa

In an article for The Conversation US, an independent news organization that publishes articles written by academics and researchers, Postdoc Aman Agrawal, Ph.D., who works with Jack Szostak lab, suggests that rainwater may have been key in stabilizing protocells, crucial for the origins of life on Earth. His research shows how coacervate droplets maintain genetic integrity, shedding light on early cellular evolution. https://lnkd.in/gNmxP6md

The Raymond Moellering lab have developed a groundbreaking synthetic molecule that targets hypoxia-inducible transcription factors (HIFs), which play a key role in tumor growth and metastasis. In tests with mice, this innovative approach successfully shrank tumors and reduced the spread of triple-negative breast cancer, a particularly aggressive form of the disease. By blocking multiple transcription factors at once, this new strategy could revolutionize cancer treatment and deepen our understanding of how tumors behave under stress. Read today to discover how their innovative approach could pave the way for new cancer treatments and deepen our understanding of how tumors behave under stress. - https://lnkd.in/gSR83SsW #CancerResearch #Innovation #UChicago #ScienceNews

?? Exciting Breakthrough in Cancer Research! ?? Researchers at the University of Chicago Department of Chemistry have developed synthetic molecules that can "turn off" cancer growth in mice. The study, published in #NatureChemicalBiology, focuses on transcription factors—proteins essential for cancer cells to grow and spread.?These proteins were long considered "undruggable," but this new molecules blocks these factors, and scientists successfully shrunk tumors and reduced metastasis in aggressive breast cancer models. This groundbreaking research could open doors for therapies that were previously unimaginable. ?? #BreastCancerResearch #BiomedicalInnovation #NewHopeForFutureTreatments Read full story here: https://ow.ly/BiVU50TKsxg

In a remarkable achievement for both the scientific community and the University of Chicago Department of Chemistry, Dr. John Jumper (PhD ’17) has been awarded 2024 Nobel Prize in Chemistry. The The Royal Swedish Academy of Sciences that awards The Nobel Prize honored Jumper, who received his Ph.D. from the University of Chicago in 2017, along with Demis Hassabis, for their work on "protein structure prediction." The award is also shared with?Prof. David Baker?of the University of Washington?"for computational protein design." John Jumper is the 19th person affiliated with the University of Chicago to receive the Nobel Prize in Chemistry and the 100th member of the UChicago community to earn a Nobel Prize. Most recently, the 2023 Nobel Prize in Chemistry was awarded to Moungi Bawendi, PhD’88, for the discovery of quantum dots; and the 2019 prize to John Goodenough, PhD’52, for the invention of lithium batteries. As the UChicago community celebrates this achievement, we look forward to the continued impact of Dr. Jumper's research on our understanding of the molecular foundations of life. Read our story to learn all about his path to innovation and excellence - https://lnkd.in/gMXBA3Pr #nobel #nobelprizewinner #nobelprize #johnjumper #nobelprizechemistry #alphafold #alphafold2 #googledeepmind

Last month The Journal of Physical Chemistry B featured a special Festschrift issue on?University of Chicago Department of Chemistry?Prof. Gregory Voth. The issue showcases 65 articles from colleagues and former students, highlighting Voth's transformative contributions to quantum mechanics, biophysics, and multi-scale modeling. We sat down with Prof. Voth to gain insight into his career journey, his work with innovative frameworks, and his dedication to mentorship, which has empowered over 200 students. From his early days as a nascent scientist to his groundbreaking contributions in theoretical chemistry, read our in-depth profile on his extraordinary career and how he continues to inspire the next generation of scientists - https://lnkd.in/eGq4Twud

In a new result supported by Q-NEXT, scientists at the University of Chicago, Argonne National Laboratory and the University of Wisconsin-Madison introduce a new hybrid quantum-classical algorithm called the LAS-USCCSD method, which is designed to solve complex #quantum chemistry problems efficiently. ? ???https://lnkd.in/gbwGVy4e ? The algorithm starts with a classical computation, calculating the basic structure and energy levels of a molecule by breaking it into smaller parts. It then selects the most important parameters, the variables that control the interaction energy between different parts of the molecule. Finally, the algorithm uses a quantum computing method called the variational quantum eigensolver to focus only on the important parameters. This makes the quantum part of the computation more efficient by reducing the amount of data the quantum computer must process. ? The new LAS-USCCSD algorithm is more efficient than its predecessor LAS-UCCSD method. It requires fewer parameters to get accurate results, so calculations are faster and simpler. This reduced complexity makes it more practical to implement on near-term quantum computers. ? The team tested the algorithm on molecules (H?)?, (H?)?, and trans-butadiene, as well as on a complex bimetallic molecule. The new method required up to 10 times fewer parameters and reduced the complexity of the quantum computations. ? Learn more:????https://lnkd.in/gbwGVy4e ? The authors of this result, published in ACS Publications’ Journal of Chemical Theory and Computation, are Abhishek Mitra, Ruhee D'cunha, Qiaohong(Joanna) Wang, Matthew Hermes, Yuri Alexeev, Stephen Gray, Matthew Otten and Laura Gagliardi. ? #quantumcomputing #quantumcomputers #quantumscience #quantuminformationscience? ? Chicago Center for Theoretical Chemistry (CCTCh) University of Chicago Department of Chemistry Pritzker School of Molecular Engineering at the University of Chicago University of Chicago Department of Computer Science University of Wisconsin–Madison Department of Physics? ?

The University of Chicago Department of Chemistry seeks an Assistant Professor of Chemistry. The University of Chicago Department of Chemistry seeks an Assistant Professor of Chemistry. Assistant Professor of Chemistry Location - Chicago, IL Position Type - Faculty - Tenure Track/Tenured Position URL - https://lnkd.in/g3gZSW5B Position Description The Department of Chemistry at The University of Chicago invites applications for tenure-track Assistant Professor of Chemistry positions in all areas of chemistry. Department members play leading roles in a wide range of research areas, including organic, inorganic, physical, materials, theoretical chemistry, and chemical biology. Joint appointments with other departments are possible. Review of applications will begin October 1, 2024, and will continue until all positions are filled or the search is closed. Qualifications At the time of hire the successful candidate must have completed all requirements for a Ph.D., or the foreign equivalent, in chemistry or a related field. Application Instructions Applicants must apply online at https://lnkd.in/gCpMRGqA and upload the following required materials: a cover letter a curriculum vitae with a list of publications a succinct outline of research plans a one-page teaching statement applicants are required to request three confidential letters of recommendation through Interfolio Equal Employment Opportunity Statement All University departments and institutes are charged with building a faculty from a diversity of backgrounds and with diverse viewpoints; with cultivating an inclusive community that values freedom of expression; and with welcoming and supporting all their members. We seek a diverse pool of applicants who wish to join an academic community that places the highest value on rigorous inquiry and encourages diverse perspectives, experiences, groups of individuals, and ideas to inform and stimulate intellectual challenge, engagement, and exchange. The University’s Statements on Diversity are at https://lnkd.in/g_e_i8DV. Apply now - https://lnkd.in/g3gZSW5B

Designing reticular frameworks is challenging. Andrea Darù came up with a powerful procedure that exploits symmetry https://lnkd.in/eifhy6He Thank you John Anderson and Davide M. Proserpio for embarking in this journey and of course thank you University of Chicago and https://lnkd.in/eaPP3RQz

Recent findings from the Jack Szostak lab for the National Academy of Sciences reveal how ancient RNA enzymes transitioned from simple phosphorimidazole substrates to more complex triphosphate substrates. This evolution highlights the adaptability and flexibility of early life forms, providing insights into the origins of biological complexity. #originsoflife https://lnkd.in/gYT8t_e9