The Karen Toffler Charitable Trust的动态

Are any other folks interested in #AI and its potential to advance #healthequity and the treatment of complex health disorders? If so, this new initiative launched by The 10,000 Brains Project and focused on #neurogenerativediseases is worth a look. ?? "... The 10,000 Brains Project has commissioned the development of a roadmap to guide the rapid adoption of AI within?neurodegeneration research. The resulting insights, including recommended approaches for addressing the key gaps and opportunities, will be shared with researchers worldwide beginning this year. The roadmap will also inform the creation of the collaborative research networks needed to rapidly move the field forward." I can't wait to see what comes of this work and how it can accelerate research efforts to treat and potentially eliminate Alzheimer's, Parkinson's, and other neurogenerative disorders. Other groups supporting this effort include the Milken Institute's Science Philanthropy Accelerator for Research Collaboration, Robertson Foundation, and The Rainwater Charitable Foundation. https://lnkd.in/gbpWv5hg #researchcollaboration

If science is the pursuit of answers, then we must ask the right questions. For Alzheimer’s researchers, the question then becomes: How do we make the biological changes to the brain in order to reduce amyloid and tau? This translates into finding the right molecule for the disease and one that will breach the blood-brain barrier which protects the brain from toxic substances in the blood but can also keep potential treatments from reaching the brain. It means ensuring that patients participating in clinical trials have Alzheimer’s disease and not a different form of dementia. It also means understanding the stage of the disease in individual patients, as well as degree of pathology. The use of imaging tools has been instrumental in answering these questions, allowing scientists and researchers to look inside the brain of patients to not only confirm the presence of amyloid and tau but also provide a view of the efficacy of potential treatments. Projects like the Alzheimer’s Disease Neuroimaging Initiative, @ https://adni.loni.usc.edu and public-private partnership to develop a longitudinal study of normal cognitive aging, mild cognitive impairment (MCI) and early Alzheimer’s disease as a public domain research resource have provided tremendous insights into disease progression. Watch the video @ https://lnkd.in/e4UAiXUG Our understanding of Alzheimer’s disease has advanced since Alois Alzheimer’s discovery more than 100 years ago. It has required commitment by academia, industry and government, and a drive and determination by numerous scientists and researchers around the world. But there’s more that needs to be done. Innovation is about connecting dots. No one person or organization alone can advance science. It’s about seeing connections among things that are going on around us, experiments in academic labs as well as clinical trials. It’s also about seeing what’s possible and then striving toward it. And that, Ladies and Gentlemen, is why we need your help in raising funds to support the reseach to find a cure for Alzheimer’s. Please join us in supporting all these efforts to find a cure for Alzheimer’s by registering and forming teams for the Walks to End Alzheimer’s throughout the nation @ https://alz.org And here in Jacksonville, @ https://lnkd.in/entDQiKU

The Women’s Alzheimer’s Movement at Cleveland Clinic recognizes that women are at the epicenter of the global Alzheimer’s epidemic and believe that cutting edge research on women’s brains is necessary to change the course of the disease. We raise money for critical women-based research and instigate the creation of women-based initiatives at leading scientific institutions, universities, foundations and organizations. We partner with leading researchers and non-profit organizations that share our vision and hope to create women’s Alzheimer’s research funds that finance high potential, gender-based scientific investigations. We are aggressively seeking answers to the question: Why are women disproportionately affected by Alzheimer’s and related dementias? Answering that question requires a sharp focus on what is particular to women’s biology, genetics, and lifestyle. While we recognize there is some gender specific research underway in labs around the country, we also know that there has not been a sufficient emphasis placed on determining the relationship between a women’s biological and genetic make-up and the fact that women are being diagnosed with Alzheimer’s, dementias and other neurological disorders at staggering rates. The myriad of gender specific factors like hormone levels, genetic composition, age-related variables, and lifestyle practices, provide a broad basis for the research that is essential to finding the answer that we hope will lead to breakthrough discoveries with far-reaching impact on the future of Alzheimer’s disease for women, men, and families everywhere. Since 2016, WAM at Cleveland Clinic has funded $4.65 million for 44 studies at 17 leading institutions and positioned its grantees to earn an additional $83 million more in government and foundation funding.

Discover empowering insights and practical advice for dealing with cancer, straight from a survivor's journey ?? Engage with the post, share with those who may benefit, and together, let's inspire strength! ?? https://wix.to/1ykkuHa #CancerCommunity #StrengthInUnity #Empowerment

We express our deepest gratitude to Mr. Deven Patel, CEO, President, and Co-founder of the Global Institute of Stem Cell Therapy and Research (GIOSTAR). His decision to join & support us is a testament to his unwavering commitment towards society. His pioneering efforts and dedication to the field of stem cell therapy have not only paved the way for groundbreaking medical treatments but have also inspired countless professionals and researchers worldwide. His leadership in promoting ISR is a beacon of hope and progress, demonstrating the profound impact that visionary leaders can have on the scientific community and society as a whole. Thank you, Dr. Deven for your relentless pursuit of excellence and for being a true leader in promoting ISR. Your contributions are invaluable, and we are incredibly fortunate to have you as a guiding force in this transformative journey. ISR Leadership believes in the power of collective action. The organization invites individuals and organizations to join in its mission by volunteering, donating, spreading awareness, and participating in advocacy efforts. #ISRLeadership #IndividualSocialResponsibility #SustainableLeadership #SocialImpact #EthicalLeadership #SocialResponsibility #CommunityLeadership #GlobalCitizenship #SustainabilityMatters #LeadingWithPurpose #SocialChange #Empowerment #SocialGood #PurposeDriven #ResponsibleLiving #LeadershipForGood #ImpactfulLeadership #SustainableFuture #LeadByExample #CommunityImpact #PositiveChange #SocialConsciousness #CorporateSocialResponsibility #MakingADifference #SustainabilityInAction #TransformativeLeadership #GivingBack #LeadWithIntegrity #Changemakers #BetterTogether

?? Calling all innovative minds in cancer research! ?? The Worldwide Cancer Research Grant Program is now accepting applications until April 2nd, 2024. ?? They are looking for projects that are bold, creative, and have the potential to revolutionize their understanding of cancer. With grants of up to ￡275,000 available, now is the time to turn your ideas into life-saving discoveries. ?? What they fund: ? Novel research with transformative potential. ? Projects of 12 to 36 months in duration. ? Fundamental, translational, or basic research. ? Multidisciplinary approaches that push boundaries. ?? For more information visit: https://lnkd.in/gxWWFZ9c ?? I'm a co-founder of DreamSpace Academy - a non-profit social enterprise tackling local socio-economic and environmental challenges through challenge-based learning, grassroots innovation, and impact venture building. ? Follow me for updates on empowerment initiatives around the world !!! #education #innovation #entrepreneurship #sustainability #opportunity #srilanka

Congratulations to Alzheimer's Association - Orange County Chapter on a sold-out InspirationALZ Gala and thank you for inviting us to serve as a Community Storyteller sponsor. One day soon, we’ll be able to tell a new story about Alzheimer’s—that of the first survivor. ?? Please join us extending our gratitude to Executive Director Deborah Levy; Senior Manager, Gala & Walk to End Alzheimer’s Sindy Thomas and volunteer co-chairs Claire D. and Joyce Catherine Wu for their inspired leadership. And shoutout to our strategic partner Creative Vortex Inc. on the dreamy gala branding and design. We’re over the moon that so many associates, partners, friends and colleagues could join us, including Brendan Ford, Carla Dack, Martin Dack, Cynthia Gibbs, PMP, Pascale Gibbs, Bridget Mills, Marc Mills, Laura Perdew, ACE, IOM and Jenny Tran. We support the Alzheimer’s Association because it is the largest nonprofit funder of Alzheimer’s and dementia research. ?? They seed, speed and lead the best dementia science worldwide. ?? The Alzheimer’s Association funds independent researchers worldwide, currently investing over $360 million in more than 1,000 single and multi-year projects in 53 countries. ??Their grants have funded some of the most instrumental research in Alzheimer’s and dementia science. In 2023, they hit a new milestone, investing $100 million in a single year. ??Incredible progress is happening with new drugs being approved by the FDA in the last 18 months to treat mild cognitive impairment and a blood test on the horizon that could be used as an early indicator of increased risk of cognitive decline. ?? Please join us! We want to partner with companies and individuals eager to help spread awareness and fundraise for a cure. Drop a comment below or message Cara Stewart. #orangecounty #storytelling #events #alzheimersawareness #eventsponsor #alzheimersassociation

The XPrize Foundation, known for fueling innovative research, has announced a $101 million prize for advancements in anti-ageing therapies. The aim is to develop treatments that can significantly reverse ageing effects in individuals aged 65-80, focusing on improving muscle, cognition, and immune function. This initiative, the largest in XPrize history, is a testament to the growing importance and potential of longevity research. At GenFlow Biosciences (LSE: GENF)(OTCQB: GENFF) we believe that ageing deserves as much attention as any other global health issue. Our approach, which employs advanced gene delivery techniques, is in the vanguard of addressing the challenges and opportunities of an ageing population. Read more here: https://loom.ly/5zPTJM4 #XPrize #longevity #healthspan #genetherapy

Want to know more about WAM at Cleveland Clinic? Here's a quick overview! The Women’s Alzheimer’s Movement at Cleveland Clinic recognizes that women are at the epicenter of the global Alzheimer’s disease epidemic and believe that cutting edge research on women’s brains is necessary to change the course of the disease. We raise money for critical women-based research and instigate the creation of women-based initiatives at leading scientific institutions, universities, foundations and organizations. We partner with leading researchers and non-profit organizations that share our vision and hope to create women’s Alzheimer’s research funds that finance high potential, gender-based scientific investigations. The myriad of gender specific factors like hormone levels, genetic composition, age-related variables, and lifestyle practices, provide a broad basis for the research that is essential to finding the answer that we hope will lead to breakthrough discoveries with far-reaching impact on the future of Alzheimer’s disease for women, men, and families everywhere. Since 2016, WAM at Cleveland Clinic has funded over $4.65 million for 44 studies at 17 leading institutions and positioned its grantees to earn an additional $83 million more in government and foundation funding. A recap: OUR MISSION Our mission is to discover why Alzheimer’s disease discriminates against women and communities of color and to prepare women and their families for the impact of Alzheimer’s disease by providing them with information and tools to help prevent the disease. OUR VISION We envision a future in which Alzheimer’s disease will no longer destroy the lives of women and their families. OUR WORK We work to change the future for women and Alzheimer’s disease by focusing on the four pillars: research, education, advocacy and clinical care.

We have a great addition to your summer reading list!?Our 2023 Annual Report is out, full of science on the cutting edge of the fight against Alzheimer’s disease.?We are proud that it once again reflects a broad spectrum of diverse research.?Since our founding 20 years ago, we have sought to take on high-risk, high-reward projects reflecting a range of innovative but rigorously established hypotheses, and we supported over 100 such efforts last year alone.? The clinical benefits achieved by the new anti-amyloid drugs are encouraging as evidence that progress is being made, but we need to do better against amyloid as a target and against the myriad other targets this complex disease implicates. In 2023 alone, we provided grants to investigations focused on: ? Triggers and mechanisms of tau misfolding and propagation; ? Deeper understanding of the drivers leading APP cleavage towards beta amyloid production;? ? Mechanisms of synaptic and circuit dysfunction and support in AD; ? Neuroinflammation and the role of brain-resident and peripheral immune cells; ? Impact of immunization on AD pathology; ? Potential for gut microbiome interventions to affect AD brain pathology; ? Molecular pathways altered by lifestyle interventions like exercise, diet, sleep, and stress management; and ? Many other promising areas of research. ? We understand the importance of unconventional ideas in scientific breakthroughs; that's why we strive to be the funder that exceptional researchers turn to for support in exploring potentially paradigm-changing concepts. We, and the researchers we support, are deeply grateful for our donors' generosity. Their contributions allow us to make these leaps forward possible. We're incredibly excited to see what discoveries unfold in the diverse range of projects we have and will fund in 2024. These discoveries hold immense promise for future therapies and a brighter future for those living with Alzheimer's. #AlzheimersResearch #ScientificDiscovery #NonProfitTransparency Cure Alzheimer's Fund https://lnkd.in/egmPXR9h