Targeted Oncology的动态

How to solve H-W genetics problems The Hardy_Weinberg principle, also known as the Hardy_Weinberg equilibrium, model, theorem, or law, states that allele and genotype frequencies in a population will remain constant from generation to generation in the absence of other evolutionary influences. These influences include mate choice, mutation, selection, genetic drift, gene flow and meiotic drive. Because one or more of these influences are typically present in real populations, the Hardy_Weinberg principle describes an ideal condition against which the effects of these influences can be analyzed. In the simplest case of a single locus with two alleles denoted A and a with frequencies f(A) = p and f(a) = q, respectively, the expected genotype frequencies are f(AA) = p2 for the AA homozygotes, f(aa) = q2 for the aa homozygotes, and f(Aa) = 2pq for the heterozygotes. The genotype proportions p2, 2pq, and q2 are called the Hardy_Weinberg proportions. Note that the sum of all genotype frequencies of this case is the binomial expansion of the square of the sum of p and q, and such a sum, as it represents the total of all possibilities, must be equal to 1. Therefore, (p + q)2 = p2 + 2pq + q2 = 1. The realistic solution of this equation is q = 1 p. The principle is named after G. H. Hardy and Wilhelm Weinberg, who first demonstrated it mathematically. Youtube video: https://lnkd.in/d6rAF9Gm #nikolaysgeneticslessons

Oligonucleotides are the modern heroes of modern science and medicine, enabling researchers to delve into the intricacies of genetics, develop innovative therapies, and push the boundaries of scientific research. They act as an important tool in unlocking new possibilities for understanding and harnessing the power of genetic information. To learn more about the application and uses of oligos in modern science and research read our latest informative blog: https://lnkd.in/dsDD38HV #Oligonucleotides #Oligo #CustomOligos #DNA #RNA #Primers #Nucleotides #GeneticCode?#PCR #PolymeraseChainReaction #MolecularBiology #GeneTherapy #PersonalizedMedicine #DNAProbes #TrivitronHealthcare

Delve into the world of human genetics as we explore recent groundbreaking discoveries that are revolutionizing our understanding of health, disease, and evolution. From unraveling the secrets of ancient DNA to cutting-edge gene editing techniques, this video will uncover the latest advancements in this rapidly evolving field. Prepare to be amazed by the incredible potential of human genetics to transform our lives and shape the future of medicine.

Structure of a virus?? ??A virus is a simple replicative structure consisting of protein and nucleic acid. #virus #cancerbiologyresearch #cancerbiology Image from: Benjamin A. Pierce - Genetics Essentials_ Concepts and Connections-Macmillan Learning (2020)

Drosophila genetics problem and solution The fruit fly, Drosophila melanogaster, is an excellent model system that has a vast set of molecular tools and mutants to dissect the genetic pathways that are responsible for the normal and abnormal cardiac function. While the majority of studies have focused on heart development in the Drosophila embryo, attention has recently focused on the structure and function of the adult fly heart as a model of human heart failure. Here we review strategies to identify novel genes and pathways that cause or modify dilated cardiomyopathy in adult Drosophila. Youtube video: https://lnkd.in/dD2FaS_U \#nikolays_genetics_lessons

How to solve crossing-over problems in Genetics Drosophila is an exceptionally useful genetic model used for the study of simple and complex behaviours, and its use has given an important insight into the molecular, cellular and evolutionary underpinnings of behaviour. Behavioral researchers study both natural variants and single-gene Drosophila mutants. Youtube video: https://lnkd.in/dgv6qweV #nikolaysgeneticslessons

all stages of mitosis cell division in one video .Yiu will be amazed by watching this. Stages are....... 1.interphase 2.prophase 3.metaphase 4.early anaphase 5.late anaphase 6.Telophase and the 7.Cytokinesis # cell division # genetics

Using preliminary results from the first 200 samples sequenced to an average depth of 30x, Nikhita Damaraju highlights the impact of read quality, length, and depth on phasing accuracy across OMIM genes. Our findings offer insights into optimizing LRS-based #haplotyping methods and will be of broad utility to the human genetics community, including clinicians and researchers.? #genomereference #nanoporeconf #longreads https://lnkd.in/eq5NZumS

12 true-false questions about molecular genetics Deoxyribonucleic acid is a molecule composed of two polynucleotide chains that coil around each other to form a double helix carrying genetic instructions for the development, functioning, growth and reproduction of all known organisms and many viruses. DNA and ribonucleic acid are nucleic acids. Ribonucleic acid is a polymeric molecule essential in various biological roles in coding, decoding, regulation and expression of genes. RNA and deoxyribonucleic acid are nucleic acids. Youtube video: https://lnkd.in/dVrppvFk \#nikolays_genetics_lessons