RWC Retina Rocks的动态

Great news! Our paper 'How long does it take to read a mammogram? Investigating the reading time of digital breast tomosynthesis and digital mammography' has been published in the European Journal of Radiology. Digital breast tomosynthesis (DBT) can improve cancer detection, but for adoption screening, it's critical to understand DBT's effect on reading time, and how this affects the workload in nationally organised breast screening programmes. Using real-life data from the PROSPECTS Trial (UK-based RCT comparing DBT to 2D mammography in screening), we found that: ? DBT reading time was double that of 2D mammography. ?? But, DBT reading time improved significantly over 9-months use. Thank you to co-authors: Dr Jonathan James, Dr Iain Darker, Dr Keshthra Satchithananda, Dr Nisha Sharma, Dr Alexandra Valencia, Dr William Teh, Dr Humaira Khan, Elizabeth Muscat, Dr Michael Michell & Prof Yan Chen The full article can be found here: https://lnkd.in/eE8QnbyZ #radiology #breastscreening #DBT #tomosynthesis #research

It’s well known that #mammography alone is considered an ineffective method for #breast #cancer #surveillance and diagnosing cancer recurrence, but from now on this statement is #outdated. #Radiodiagnosis Department at Kasr AlAiny School of Medicine, Cairo University, in collaboration with Baheya Foundation for early breast cancer and treatment, performed a #pioneer study in the field of #breast #imaging that aimed to evaluate the ability to use #artificial #intelligence (AI) for reading digital mammograms to #exclude #recurrence in the #operative bed of known breast cancer following the different surgical procedures: #lumpectomy, #quadrantectomy, #oncoplastic_surgery, and #reconstructive_surgeries (post-mastectomy) presented by #autologous_tissue_flaps or #prosthetic_implants. The AI scoring percentage for a clear operative bed ranged from 0% to 26%, with a mean of 15%. Operative bed benign changes displayed a score range from 10% to 88%, mean 48.2%, and malignancy recurrence range from 65% to 99%, mean 87.7%. The optimum cut-off #value to distinguish between benign postoperative changes and malignancy recurrence was 56.5% (95%, CI 0.824–1.060, p value <0.001). #Reconstructive surgeries with autologous #implants showed a range AI scoring of 19.6% to 14.7%, for intact implants. Implants that showed #intracapsular_rupture -confirmed by MR imaging- displayed a score range of 45% to 67%, and a mean of 58.7% + 11.9%. Further investigations yet to come involving AI and integrity of silicone implants. Methods: Lunit Cancer Screening AI-MMG, on digital mammography. Dual-energy contrast-enhanced mammography unit; *Amulet Innovality (FUJIFILM Healthcare Middle East & Africa Global Company, Japan) and *Senographe Pristina 3D machine (GE HealthCare, United Kingdom). #digitalmammography, #artificialintelligence #breastcancer #suspiciouslesions, #cancer_recurrance #post_operative_changes, #reconstructive_breast_surgeries

What does it take to be a #urology cancer surgeon? Earlier this year, we spoke to Professor David Nicol, a Consultant Urologist specialising in kidney and testicular cancer as well as surgery for adrenal and retroperitoneal tumours, about his career. He talked to us about how he started his surgical career, why kidney cancers can be difficult to treat, and what he considers to be the most important aspect of being a surgeon. "Technical skills are an important part of surgery, as is the operative strategy. But a fundamental element that makes us surgeons is knowing when to stop. It's not actually a technical skill, but more a thought process - to realise that you won't be achieving anything and you could be doing harm by proceeding. "I think the principle 'do no harm' is very, very important. As surgeons, we make plans to balance against any level of harm the patient may have. One of the reasons we have multidisciplinary team meetings is so that every point of view is canvassed in coming to the treatment decisions or recommendations we make." "Most kidney cancers develop over many years. And unfortunately, as a consequence of this, many can present very late at a very large size where surgery and other treatment options may be limited. "At The Royal Marsden, we work in a cancer institution so meeting people with cancer is part of our every day. And there are good outcomes and bad outcomes. We are fortunate in seeing very spectacular, wonderful outcomes, but at the same time need to accept that we can't achieve that every time. "I was attracted to surgery because it's a specialty where you see an immediate and direct impact of the treatment that you've provided to a person. With an operation, if it's involving cancer, within a few short hours, you can remove and eradicate the cancer from that patient. "Obviously, they need to take time to recover and return to normal activities. But with one single definitive act, you've had a profound effect on that patient's life and hopefully life expectancy." --- Professor David Nicol features in episodes 1 and 4 of Super Surgeons: A Chance at Life. You can catch up on #SuperSurgeons: A Chance at Life on Channel 4's streaming service. https://bit.ly/3zLnHH6

This approach can be applied to much more than surgery.

Welcome to Case Solution with EURORAD! ??Differential Diagnosis: ?? Male breast cancer ?? Fat necrosis of the breast ?? Metastatic nodule in the breast ?? Nodular fasciitis ?Final diagnosis: US-guided biopsy revealed the diagnosis of FAT NECROSIS ??Highlights: ?? Gynecomastia: The most common male breast condition. Causes include hormonal imbalances, neoplasms, cirrhosis, medications, aging, and genetic factors. MX: Three main radiological patterns: nodular, dendritic, and diffuse. The dendritic pattern, indicative of long-standing irreversible gynecomastia, shows a flame-shaped density with deep linear extensions. Early treatment can reverse gynecomastia before fibrosis sets in. ?? Fat Necrosis: Rare in men, often asymptomatic and results from trauma, prior breast surgery, radiotherapy, and anticoagulant use. It can mimic breast cancer, both clinically and radiologically. MX: Key radiological features include radiolucent round masses in early stages, and dense masses or distortion when fibrosis advances. MX findings might be the only indicators, showing eggshell or suspicious microcalcifications. ??Take homes: ?? Radiologists should be aware of male breast conditions despite their rarity. ?Gynecomastia has distinct radiological patterns and may be reversible in early stages. ?Fat necrosis, although rare, can closely resemble breast cancer and requires a detailed assessment. ?Biopsy is crucial when imaging is inconclusive. ?Case courtesy by Eurorad, CASE: 12852 Prepared by Gianmarco Della Pepa, Italy ???? ?Stay tuned for the next ??#eusobicases ?? #radiology #breastimaging #breastradiology #breastcancer #mammography#ultrasonography #breastcases#radiologycase #mri #breastmri #dwi #adc #medicalimaging #radiologyeducation #screening #eusobi #casetuesday #eusobiyoungclub #EYC #eusobicases #EURORAD Gianmarco Della Pepa

?? PSA Tests & Prostate Surgery: Do They Really Save Lives? ?? New 15-Year Study Reveals Surprising Truth! ?? ?? Today, let's explore an important topic about men's health. We'll talk about PSA testing and prostate surgery and what a long study found out. ?? Imagine a brave knight protecting his castle. ?? This castle is like your body, and the knight is the PSA test, trying to guard against prostate cancer. But sometimes, even the bravest knight can't make a big difference. A study involved over 415,000 men aged 50 to 69 years. They were split into two groups: one got a single invitation for a PSA test, and the other didn't. Researchers watched them for 15 years, like observing how well our knight guards the castle over a long time. The study asked a simple question: "Does the PSA test save lives?" ?? Here's what they found: - In the group invited for PSA testing, 0.69% of men died from prostate cancer. - In the group without the test, 0.78% of men died from prostate cancer. - This means the difference is just 0.09%. So, inviting men for a PSA test saved some lives, but the number is very small. Think of it like rain on a dry land. ??? The PSA test is like a few drops of rain. It helps, but not much. The researchers concluded that while PSA testing can reduce deaths from prostate cancer, the benefit is tiny. It's like using a small shield to protect against a big dragon. ????? So, what should we do? It's essential to talk to your doctor. Discuss the pros and cons of PSA testing. It's also important to focus on overall health—exercise, eat well, and stay informed. Remember, knowledge is like light guiding us through the dark forest of uncertainty. ??? Together, we can make the best choices for our health and well-being. Thank you for listening. Stay healthy, stay informed, and keep shining bright! ?? Evidence ?? JAMA. April 6th 2024 2024;331(17):1460-1470. doi:10.1001/jama.2024.4011 #MenHealth #ProstateCancer #PSATest #HealthAwareness #MedicalResearch #StayInformed #CancerPrevention #HealthyLiving #MedicalStudy #ProstateHealth #HealthAwareness #MedicalResearch #Υγε?αΑνδρ?ν #Καρκ?νο?Προστ?τη #Ενημ?ρωσηΥγε?α? #Ιατρικ??ρευνα

A 58-year-old male presented with a 2-month history of hoarseness, left tonsillar swelling, and headaches. Clinical examination revealed a visible left tonsillar mass intraorally, with no external neck swelling. MRI angiography initially suggested a Type 3B carotid tumor, indicating possible internal carotid artery (ICA) encasement or a vagus/hypoglossal nerve schwannoma. Due to the complexity of the case, we planned a transcervical excision of the parapharyngeal tumor, with contingencies for ICA resection and Dacron graft placement if needed, with vascular surgery team backup. We also considered a mandibulotomy for enhanced exposure, if required. Intraoperatively, however, we found that the ICA was only partially encased rather than fully encased, as the imaging reports had indicated. This allowed us to successfully dissect the tumor from the ICA without injury. Additionally, this was not a carotid body tumor but a large mass extending from just above the carotid bifurcation up to the skull base, reaching beyond the C1 vertebra, and positioned laterally to the carotid artery. The tumor was tightly adherent at the carotid canal, with the vagus nerve enveloped by the mass. After carefully releasing it from the?carotid canal, we successfully delivered the tumor, thus negating the need for a mandibulotomy. All major vessels, including the carotids, internal and external jugular veins, were preserved, as well as the hypoglossal and spinal accessory nerves. As the vagus nerve was engulfed by the tumor, it was sacrificed. Dr. Vishal Vora, our plastic surgeon, performed a microneural anastomosis using a cable graft from the greater auricular nerve. Postoperatively, the patient demonstrated an excellent outcome, with a well-compensated vocal cord on endoscopy, minimal voice changes, and no aspiration issues. He was discharged in stable condition on the third postoperative day and is expected to achieve full recovery within a month. This case underscores the importance of precise surgical planning and adaptability, as intraoperative findings can often challenge preoperative imaging. Our multidisciplinary approach allowed us to achieve a successful outcome while preserving vital structures. - This case was performed by Dr.Bhavin Vadodariya of SSO Team Ahmedabad. #cancer #headandneckcancer #cancercare #Cancercure #cancertreatment #cancerpatients #cancerdoctors #multidisciplinary #operation #canceroperation #surgicalplanning #cancerhospital #hospital #oncosurgeon #hospitals #doctors #oncology

New?? Placental growth factor promotes #neuralinvasion and predicts disease prognosis in resectable #pancreaticcancer ---------------- Surgery represents the only curative treatment option for pancreatic ductal adenocarcinoma (PDAC), but recurrence in more than 85% of patients limits the success of curative-intent tumor resection. Neural invasion (NI), particularly the spread of tumor cells along nerves into extratumoral regions of the pancreas, constitutes a well-recognized risk factor for recurrence. Hence, monitoring and therapeutic targeting of NI offer the potential to stratify recurrence risk and improve recurrence-free survival. Based on the evolutionary conserved dual function of axon and vessel guidance molecules, we hypothesize that the proangiogenic vessel guidance factor placental growth factor (PlGF) fosters NI. To test this hypothesis, Christian Fischer et al. correlated PlGF with NI in PDAC patient samples and functionally assessed its role for the interaction of tumor cells with nerves. Look here ?? https://lnkd.in/gRw3dVNd #Placentalgrowthfactor #Cancerneuroscience IFO - Istituto Nazionale Tumori Regina Elena - Istituto Dermatologico San Gallicano

Make Mondays Matter! ?? Schedule your Breast Sonography appointment Every Monday from 7-9 PM. Breast sonography, also known as breast ultrasound, is an important diagnostic tool for several reasons: Early Detection of Breast Cancer: It helps in the early detection of breast cancer, which can significantly improve treatment outcomes and survival rates. Evaluation of Abnormalities: It is used to further evaluate abnormalities found in mammograms or physical exams, such as lumps or other suspicious areas in the breast. Guidance for Biopsies: It provides guidance for needle biopsies, ensuring precise sampling of suspicious tissues. Differentiation of Cysts and Solid Masses: It helps distinguish between fluid-filled cysts and solid masses, aiding in accurate diagnosis and treatment planning. Assessment of Blood Flow: Doppler ultrasound, a specialized form of breast sonography, can assess blood flow in breast lesions, helping to determine the nature of the abnormality. Non-Invasive and Radiation-Free: It is a non-invasive procedure that does not use ionizing radiation, making it safe for repeated use and suitable for pregnant women and those who need frequent monitoring. Supplementary to Mammography: It is particularly useful for women with dense breast tissue where mammography may not be as effective, providing additional clarity and information. Regular breast sonography can lead to early intervention, better management of breast health, and increased peace of mind. Prioritize your health and book now for peace of mind. ?? #breastsonography #breastultrasound #sonography #radiologist #vanshhospital #vanshfamily

?? Exciting News! ?? Happy to share that the research conducted by my honors student, Celest Leo, last year has been published in Breast Cancer Research and Treatment! Special thanks to Prof Linda Hong-Gu HE, PhD, MD, RN, FAAN for engaging me in the co-advisory role! ?? Title: "Global prevalence and factors associated with preoperative depression in women undergoing breast surgery: a meta-analysis and meta-regression" This research stemmed from my umbrella review, revealing a critical gap in understanding preoperative depression in women undergoing breast surgery, despite its significant impact on postoperative outcomes, such as impaired recovery and adverse surgical outcomes. ?? Objectives: Therefore, our review aimed to synthesize the prevalence rate of preoperative depression among breast cancer patients and explore associated factors. Drawing from 20 studies involving 32,143 patients, our analysis revealed several key findings: ?? Key Findings: 1) Global prevalence of preoperative depressive symptoms among patients with breast cancer was 29% (95% CI 19–40%). 2) Studies conducted in the Middle East and North Africa, utilizing purposive sampling, reported higher prevalence rates of preoperative depression (54%, 44%, 40%, and 49%, respectively) compared to other subgroups. ?? Conclusion: Healthcare professionals should assess the psychological well-being of these patients before surgery and provide adequate support to those experiencing depressive symptoms preoperatively. This will ensure that patients receive comprehensive care and healing. Read the full article, here: https://lnkd.in/gUpcBB_r #Breastcancer #Depression #Metaanalysis #Preoperative #Surgery #Systematicreview