Pharmacopsychiatry Journal的动态

?? An excellent #Review to read this #weekend! Systematic Review and Meta-Analysis of L-Methylfolate Augmentation in Depressive Disorders ? by Abdullah M., Ethan Poweleit, Lisa C. Brown, PhD, Jeffrey Strawn, and Chad Bousman ?? Almost one in five people experience one episode of major depressive disorder (MDD) at some point in their life that severely impacts #psychosocial functioning and diminishes their quality of life. ? ?? Partial response to #pharmacotherapy is common in MDD and many patients require alternative pharmacotherapy or augmentation, including adjunctive L-methylfolate. ? ?? Given that L-methylfolate augmentation is rarely included in major clinical practice guidelines, this Review sought to systematically review evidence for L-methylfolate augmentation in adults with MDD and to examine its efficacy meta-analytically. ? ??Read the full article on: https://lnkd.in/duVE7ep5 ? #MentalHealth #MajorDepressiveDisorder