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Understanding Protein-Protein Interactions with BioID, BioID2, TurboID, and miniTurbo In biological research, mapping protein-protein interactions (PPIs) is key to unlocking cellular functions. But which proximity labeling technology is best for your research? Our infographic compares BioID, BioID2, TurboID, and miniTurbo—each with unique advantages depending on your study's goals, from long-term interaction mapping to rapid dynamic studies. ?? Learn more and choose the right technology for your research: https://lnkd.in/g8VSEkJD #BioID #Bioinformatics #PPIs

The FractioMate, an analytical product for high throughput Effect Directed Analysis developed by the VU and brought to you together with Bruker in 2025! ? How do you identify biologically active, toxic compounds in water?????? Persistent, mobile, and toxic compounds (PMT) are increasingly threatening our drinking water resources. To safeguard life, we must address emerging contaminants like pharmaceuticals, endocrine-disrupting compounds, and perfluorinated compounds. These pose serious health and environmental risks, including DNA damage, developmental disruption, reproductive issues, and cancer. Effect-directed analysis (EDA)?is a key method for testing the biological activities of these compounds. Though traditionally lengthy, involving activity monitoring, fractionation, repeated bioassay testing, and chemical analysis, there's a game-changer. Together with our partner #Bruker, the #AIMMS scientists Dr. Jeroen Kool and Prof. dr. Marja Lamoree (#Vrije Universiteit Amsterdam)?brings the?#FractioMate, which, when paired with high-resolution mass spectrometry, simplifies the traditionally complex, costly, and time-consuming studies. This cutting-edge solution enables robust, rapid, and sensitive analyses, boosting the identification of biologically active compounds to 5-10 samples per week and greatly enhancing the detection of toxic compounds. #EnvironmentalScience #WaterQuality #AnalyticalChemistry #SustainableSolutions #ResearchInnovation ?? Watch the video to learn more!?? https://lnkd.in/ecqkSD7q Photo: Right: dr. Jeroen Kool in front of two FractioMates. Left: prof. dr. Marja Lamoree in front of a Bruker TIMS TOF pro2 mass spectrometer. Jeroen and Marja developed and commercialized the FractioMate.

Exciting news for those interested in the intersection of biology and technology! Our latest blog post explores the fascinating concept of "Animals as Chemical Factories." This insightful piece delves into how animals can be harnessed to produce valuable chemical compounds, revolutionizing industries such as pharmaceuticals and biomanufacturing. Discover the innovative research and potential applications that could reshape our understanding of bio-production. Read more about this groundbreaking topic here: https://ift.tt/mb3BAEa.

As the demand for high-quality proteins continues to rise across research, diagnostics, and therapeutics, scientists are pushing the boundaries of discovery and development with cutting-edge technologies. At PepTalk 2025, the Higher Throughput Pipeline features three must attend tracks you won’t want to miss: Predictive Protein Production: Disruptive Tools for Capturing Data More Efficiently and Applying Analytics More Effectively ?? January 13, 2025 This symposium will showcase innovations in screening and assay technologies that are transforming predictive protein production. Discover how advancements in data capture and analytics are optimizing production and driving new possibilities. Automation in Protein Sciences: Applying Robotics, Automation, and Analytics to Optimize Workflows and Quality ?? January 14-15, 2025 Learn how high-throughput screening, real-time monitoring, and advanced data analytics are enhancing productivity and quality in protein science. Gain actionable insights on using automation and robotics to streamline your workflows. Cutting-Edge Tools for Purification and Quality Assurance: Streamlining Biopharmaceutical R&D by Overcoming Bottlenecks and Unlocking Efficiency ?? January 16-17, 2025 Explore innovative tools and strategies to tackle bottlenecks in purification and quality assurance. Discover ways to improve efficiency and accelerate the path from research to market. By attending these tracks, you’ll gain the latest insights and technologies from industry experts to help you stay ahead in the ever-evolving field of protein science. ??? Register Now and join us at PepTalk2025! https://lnkd.in/gtaxY7Bz #CHIPepTalk #ProteinScience #Automation #Biotech #Purification #QualityAssurance #HighThroughput

Revolutionize Your Protein Research with Co-Immunoprecipitation Mass Spectrometry (Co-IP-MS)! ? Our Co-IP-MS platform combines selective protein capture with high-resolution mass spectrometry, allowing for unparalleled detection and characterization of protein interactions. Why Choose Co-IP-MS? ? Comprehensive Identification: Detects all proteins within a complex, including novel and unknown partners. ? Quantifies Protein Interactions: Compares protein abundance, providing insights into dynamics and stoichiometry. ? Maps Interaction Networks: Constructs detailed networks, revealing functional relationships. ? No Prior Knowledge Required: Identifies all co-precipitated proteins, enabling novel discoveries. ? High Throughput: Facilitates the study of complex biological processes efficiently. ? Physiologically Relevant: Preserves native protein conformations for identifying relevant interactions. Download our PDF to learn more and see how Co-IP-MS can advance your research. Contact us today! #Proteomics #MassSpectrometry https://lnkd.in/g4ewxx9f

?? If you missed our poster on high-throughput epitope mapping and in-solution protein analysis, check out this video where we walk through the highlights! ?? Discover how Immuto Scientific’s radical footprinting platform provides high-resolution insights in live cells, delivering critical data for antibody discovery and ligand interactions. Or, if you’re attending #PEGS2024, stop by Poster 55 to see Hetal present it live! #AntibodyTherapeutics #AntibodyEngineering #Biotech #Innovation #AntibodyDesign #LifeScience #PEGS #Antibody

Are you a company looking to test how bacteria respond to antimicrobial compounds? ?? The TraDIS-Xpress team have developed a cutting-edge whole genome assay that identifies genes impacting bacterial fitness under various conditions. By using extremely dense and highly saturated mutant libraries, we achieve base pair resolution in identifying fitness differences, while enabling the study of essential genes that cannot be inactivated by other methods. Check out QIB Extra ’s new TRADIS-Xpress service. The TraDIS-Xpress team have developed a suite of highly saturated transposon mutant libraries across various organisms of interest, available commercially. These libraries can identify fitness differences in each test condition at base pair resolution. Find out more ?? https://buff.ly/4bUleIs #Antimicrobial #Biotech #Innovation

Are you at #PEGS2024?! Stop by Booth #505 for an unparalleled convergence of expertise and innovation! Learn more on latest advancements, connect with industry experts, and explore groundbreaking research shaping the future of protein engineering. #proteinengineering #bioengineering #biotech

?? Ensuring scientific rigor and reproducibility is key to life science research. By citing the specific antibody, clone number, and manufacturer, researchers can improve transparency, reproducibility, and impact of scientific findings. ICL gives customers access to reagent citations directly on our product pages, allowing research and diagnostic teams to learn how ICL products are used across the industry. Learn more about reagent citations in our latest blog article: https://lnkd.in/gMHMxB-n #science #research #blog #manufacturer #antibodies #ELISA #ICL #biotech #lifescience

Exploring Pharmacophore Modeling Ever wondered how scientists identify potential drug candidates? Enter pharmacophore modeling! A pharmacophore is the blueprint of a molecule, highlighting its key features necessary for optimal interactions with a biological target. These features include hydrogen bond donors/acceptors, acidic/basic groups, and hydrophobic moieties. Using 3D-pharmacophores, scientists conduct virtual screenings of databases through docking experiments, swiftly extracting diverse leads in terms of structure. Initial screenings often apply filters like Lipinski’s Rule or drug-like ADME properties to pinpoint promising candidates. #PharmacophoreModeling #MoldrugAISystems#DrugDiscovery #Science #Medicine #Research #Bioinformatics