OmicsLogic - Biology as Data Science的动态

Next-generation sequencing (NGS) is transforming the way we detect, understand, and combat infectious diseases. ???? The ?????? ?????? ???????????????????? ???????????????? course track offers hands-on projects that dive deep into real-world challenges: ??????????-???? ???????????? & ????????????????????????: Investigate SARS-CoV-2 mutations and entry mechanisms. ???? ???????????????????? ??????????????????: Analyze key viral mutations through NGS. ???? ????-?????? & ?????????? ?????????????? ????????????????: Examine the genetic factors behind outbreaks. ???? ????????-??????-?? ?????? ????????????????????????: Monitor variants of concern using NGS data. ???? ???????????????????????? ??????????????????: Explore antibiotic resistance in ??????. ???? ???????? ?????????? ??????????????????????????????: Discover genes linked to persistent symptoms. ???? To learn more about the Course Track, visit: https://lnkd.in/ebBjpWeK #Bioinformatics #NGS #Genomics #InfectiousDiseases #PathogenGenomics #PublicHealth #AntibioticResistance #GenomicSurveillance #ViralGenomics #COVID19Research #LongCOVID #PandemicResearch #MicrobialGenomics #Omics #Metagenomics #Transcriptomics

Next-generation sequencing (NGS) is revolutionizing how we detect, understand, and combat infectious diseases. ???? We are excited to announce the launch of the ?????? ?????? ???????????????????? ???????????????? course track, featuring six hands-on projects: - ??????????-???? ???????????? & ????????????????????????: Explore SARS-CoV-2 mutations and entry points. ???? - ???????????????????? ??????????????????: Track key viral mutations using NGS. ???? - ????-?????? & ?????????? ?????????????? ????????????????: Study genetic links between outbreaks. ???? - ????????-??????-?? ?????? ????????????????????????: Analyze variants of concern. ???? - ???????????????????????? ??????????????????: Investigate antibiotic resistance in ??????. ???? - ???????? ?????????? ??????????????????????????????: Identify key genes linked to symptoms. ???? ???????????????? ?????? ???? ???????????????? ?????? ????????: https://lnkd.in/ebBjpWeK #Bioinformatics #NGS #Genomics #Omics #Transcriptomics #Metagenomics #InfectiousDiseases #NGSforResearch #PathogenGenomics #ViralGenomics #MicrobialGenomics #PublicHealth #PandemicResearch #AntibioticResistance #COVID19Research #LongCOVID #GenomicSurveillance

Next-generation sequencing (NGS) is transforming the way we detect, understand, and combat infectious diseases. ???? The ?????? ?????? ???????????????????? ???????????????? course track offers hands-on projects and in-depth lessons, giving participants a comprehensive understanding of how NGS is applied to real-world infectious disease challenges. Learn to investigate the origins and mutations of viruses, track variants of concern, and explore genomic data for disease management and research. Key lessons include: ??????????-???? ???????????? & ????????????????????????: Dive into SARS-CoV-2 mutations and entry mechanisms. ???? ???????????????????? ??????????????????: Analyze viral mutations through NGS. ???? ????-?????? & ?????????? ?????????????? ????????????????: Study the genetic factors behind this outbreak. ???? ????????-??????-?? ?????? ????????????????????????: Monitor and analyze variants of concern. ???? ???????????????????????? ??????????????????: Investigate antibiotic resistance in ??????. ???? ???????? ?????????? ??????????????????????????????: Explore genes associated with prolonged symptoms. ???? Through these modules, you'll gain valuable insights into using NGS technology for diagnosing and combating infectious diseases. Plus, you'll explore the integration of open-source tools, databases, and pipelines essential for NGS data analysis—making this course ideal for biologists, bioinformaticians, and researchers looking to advance their skills in pathogen genomics. ???????????? ???????? ???? https://lnkd.in/ebBjpWeK #Bioinformatics #NGS #Genomics #InfectiousDiseases #PathogenGenomics #AntibioticResistance #GenomicSurveillance #ViralGenomics #COVID19Research #MicrobialGenomics #PublicHealth #OmicsDataAnalysis #DataScience #Biology #Transcriptomics #Metagenomics

Next-generation sequencing (NGS) is transforming the way we detect, understand, and combat infectious diseases. ???? The ?????? ?????? ???????????????????? ???????????????? course track offers hands-on projects and in-depth lessons, giving participants a comprehensive understanding of how NGS is applied to real-world infectious disease challenges. Learn to investigate the origins and mutations of viruses, track variants of concern, and explore genomic data for disease management and research. Key lessons include: ??????????-???? ???????????? & ????????????????????????: Dive into SARS-CoV-2 mutations and entry mechanisms. ???? ???????????????????? ??????????????????: Analyze viral mutations through NGS. ???? ????-?????? & ?????????? ?????????????? ????????????????: Study the genetic factors behind this outbreak. ???? ????????-??????-?? ?????? ????????????????????????: Monitor and analyze variants of concern. ???? ???????????????????????? ??????????????????: Investigate antibiotic resistance in ??????. ???? ???????? ?????????? ??????????????????????????????: Explore genes associated with prolonged symptoms. ???? Through these modules, you'll gain valuable insights into using NGS technology for diagnosing and combating infectious diseases. Plus, you'll explore the integration of open-source tools, databases, and pipelines essential for NGS data analysis—making this course ideal for biologists, bioinformaticians, and researchers looking to advance their skills in pathogen genomics. ???????????? ???????? ???? https://lnkd.in/ebBjpWeK #Bioinformatics #NGS #Genomics #InfectiousDiseases #PathogenGenomics #AntibioticResistance #GenomicSurveillance #ViralGenomics #COVID19Research #MicrobialGenomics #PublicHealth #OmicsDataAnalysis #DataScience #Biology #Transcriptomics #Metagenomics

Next-generation sequencing (NGS) is transforming the way we detect, understand, and combat infectious diseases. ???? The ?????? ?????? ???????????????????? ???????????????? course track offers hands-on projects and in-depth lessons, giving participants a comprehensive understanding of how NGS is applied to real-world infectious disease challenges. Learn to investigate the origins and mutations of viruses, track variants of concern, and explore genomic data for disease management and research. Key lessons include: ??????????-???? ???????????? & ????????????????????????: Dive into SARS-CoV-2 mutations and entry mechanisms. ???? ???????????????????? ??????????????????: Analyze viral mutations through NGS. ???? ????-?????? & ?????????? ?????????????? ????????????????: Study the genetic factors behind this outbreak. ???? ????????-??????-?? ?????? ????????????????????????: Monitor and analyze variants of concern. ???? ???????????????????????? ??????????????????: Investigate antibiotic resistance in ??????. ???? ???????? ?????????? ??????????????????????????????: Explore genes associated with prolonged symptoms. ???? Through these modules, you'll gain valuable insights into using NGS technology for diagnosing and combating infectious diseases. Plus, you'll explore the integration of open-source tools, databases, and pipelines essential for NGS data analysis—making this course ideal for biologists, bioinformaticians, and researchers looking to advance their skills in pathogen genomics. ???????????? ???????? ???? https://lnkd.in/ebBjpWeK #Bioinformatics #NGS #Genomics #InfectiousDiseases #PathogenGenomics #AntibioticResistance #GenomicSurveillance #ViralGenomics #COVID19Research #MicrobialGenomics #PublicHealth #OmicsDataAnalysis #DataScience #Biology #Transcriptomics #Metagenomics

????As a scientist, few things are more fulfilling than seeing the fruits of countless days and nights of hard work shared with the world. With immense dedication, we are thrilled to announce the publication of one of the most comprehensive studies on Staphylococcus aureus using whole-genome sequencing in Ghana??! Over the past three years, we collected S. aureus isolates implicated in infections from 10 hospitals across Ghana. Using advanced genomic sequencing and bioinformatics tools, we delved into their genetic makeup to uncover critical insights. ??Our findings shed light on how this organism is evolving over time, the strategies it employs to survive in our environment, evade antibiotics, and enhance its pathogenicity. ??A particularly striking discovery was the high prevalence of methicillin-resistant S. aureus (MRSA), especially the ST152 clone. This strain, once predominantly methicillin-sensitive, has evolved into being predominantly MRSA . ST152 is a pandemic clone known to cause hospital outbreaks globally—a concerning development with significant implications for infection control. ??This study underscores the critical need for genomic surveillance in combating antimicrobial resistance (AMR). Integrating such innovative approaches into public health strategies cannot be overstated. ????A heartfelt thank you to SeqAfrica DTU Team for their unwavering support, to Beverly Egyir, PhD for her outstanding leadership, mentorship, and guidance as principal investigator, and to the incredible NMIMR AMR Hub Seqfrica team for their hard work and collaboration ??. For more details, check out the paper—it’s a compelling read!?? https://lnkd.in/e6QN7T6c

[New Publication with focus on Carrier screening] Title: Prevalence of common autosomal recessive mutation carriers in women in Southern Vietnam following the application of expanded carrier screening. ??Variant interpretation was carried out utilizing the ???????????? ???????????????? platform. ??The study recruited 338 women and conducted pre-test counseling, obtaining blood samples for ECS of 540 genes using NGS. ??63.6% of participants were found to be carriers for at least one recessive disease. Read the full publication from Nature Portfolio summarized by Geneyx Genomex Ltd. here. https://lnkd.in/dS-J8-8s #carrierscreening #screeningtests #prenatal #genomics #healthcare #NGS

The extensive variety of bacteriophages and their bacterial counterparts makes it challenging to foresee phage-bacteria dynamics due to largely unknown genetic influences. This investigation employs machine learning to forecast interactions between 51 Escherichia coli strains and 45 phage λ variants over a 37-day period. Utilizing genomic sequences and phenotypic data, the model estimates which phages infect specific bacteria and gauges infection levels among 2,295 possible interactions. The approach effectively predicted 86% of the interactions and improved accuracy in infection strength predictions by 40%. Significant mutations impacting interactions were identified, including both known and novel mutations influencing bacterial resistance. This technique could enhance the identification of genetic determinants in intricate phage-bacteria ecosystems. #Microbiology #MachineLearning

Explore the intricate realm of Genomic Mutations, their impacts on health, and advances in detection and management strategies. https://lnkd.in/gq3TqEwY #apgxa #pgx #pharmacogenomics #genomics #mutations #genomicmutations #omics

New Feature Alert! Phased variants can be a challenge, but our latest blog covers how to collapse phased variants in VarSeq like a pro! Whether you're working with rare disease analysis or complex genotype cases, this functionality is a game-changer for your research. Check out the step-by-step guide now and see how VarSeq streamlines variant interpretation! Learn more here: https://bit.ly/47orIh7 #Genomics #NGS #RareDisease #VarSeq #PhasedVariants #VariantAnalysis #PrecisionMedicine #Bioinformatics