Mount Sinai Department of Medicine转发了
Mount Sinai researchers have made a significant breakthrough by uncovering how targeting gut-associated lymphoid tissue (GALT) plays a critical role in managing chronic inflammation in UC and Crohn’s disease. This discovery, published in Science Immunology, sheds light on the role of the integrin receptor α4β7 on white blood cells, including dendritic cells and T and B lymphocytes, in driving inflammation. “Our latest research helps us develop biomarkers based on real biology, leading to a better understanding of how individual patients respond to IBD treatments,” explains Dr. Saurabh Mehandru, who has led a mucosal immunology lab at Mount Sinai for over a decade. Learn more: https://bit.ly/4fVgHao Mount Sinai Department of Medicine
