Johnny Clark的动态

I'm interested to hear from Sports Medicine and Orthopaedic Sports Surgeons regarding your experience with adipose-derived Mesenchymal Stem Cells vs HA injections (Durolane, Synvisc, Euflexxa) etc for the management of arthritis in patients not suitable for or not wanting joint replacement. #stemcells #arthritis

Our team is thrilled to share the latest findings published in the Journal of Aging Research and Healthcare. ?? ?? Title: Venous Thromboembolism after Orthopaedic Surgery – How Long is the Patient at Risk? ?? Summary: This groundbreaking study delves into the risk of venous thromboembolism (VTE) post-orthopaedic surgery, shedding light on crucial insights. Researchers examined patients who experienced VTE within one year after surgery, uncovering significant findings. ?? Key Points: Risk Factors Identified: Obesity, personal/family history of DVT, cardiovascular disease, and lower limb arthroplasty were confirmed as pre-established risk factors. Extended Risk Period: Patients with known risk factors may remain susceptible to VTE for a longer duration than previously thought, even with post-operative thromboprophylaxis. Call for Further Investigation: The study suggests the need for additional research to determine if enhanced VTE prophylaxis is warranted for this population. ?? Dive deeper into the study for a comprehensive understanding: https://lnkd.in/g22FU-5D Join the conversation and stay informed about the latest advancements in healthcare research! ?? #MedicalResearch #VTE #OrthopaedicSurgery #HealthcareScience

We are pleased to announce the publication of our study, "Effectiveness and Safety of Polyacrylamide Hydrogel Injection for Knee Osteoarthritis: Results from a 12-Month Follow-Up of an Open-Label Study," in the Journal of Orthopaedic Surgery and Research. This study evaluates the longer-term effectiveness and safety of a novel injectable polyacrylamide hydrogel (iPAAG) for knee osteoarthritis (OA). The initial findings demonstrated efficacy and safety for up to 26 weeks. Our latest results extend this data to a 12-month follow-up, providing robust evidence of sustained benefit for knee OA patients. Link to research article: https://ow.ly/AzIc50SwjHs #ClinicalResearch #Orthopedics #KneeOsteoarthritis #JointHealth #MedicalInnovation #OsteoarthritisTreatment #HealthcareResearch #Arthrosamid #iPAAG

May 17, at 13:00h, Dani?l Janssen will defend his PhD thesis titled "???????????????? ???????? ???????????????????? ???? ?????????????????????? ????????????????" at Universiteit Maastricht. ???Watch the video of the PhD defence ceremony here:?https://lnkd.in/eQNNeWdk ?? Link to thesis: https://lnkd.in/eMcseKQ9 **??????????????** Because orthopaedic procedures with total joint prosthesis and instrumented spinal fusion have shown good results, with an increase of quality of life, a further increase of these procedures in the coming decades is expected, with more aged patients, more revision procedures, but also more younger patients who will undergo these procedures. Unfortunately, orthopaedic implants have a risk for bacterial infection. In literature the incidence of surgical site infection (SSI) after spinal surgery ranges from 2 to 12%, depending on diagnosis, surgical approach, use of spinal instrumentation, and the complexity of the procedure. The incidence of prosthetic joint infection ranges between 1-2% in literature, and may be increasing just as the incidence of SSI after spinal surgery. Promotores: Prof. dr. P.C. Willems, Prof. dr. L.W. van Rhijn Co-promotor: Dr. J.A.P. Geurts #MaastrichtUniversity?#CAPHRI #SurgicalSiteInfections #OrthopaedicImplants

Mesenchymal SCs for Knee OA. This comprehensive analysis includes 16 randomized controlled trials and cohort studies, encompassing a total of 1005 patients. ?????????? Key Findings: - Efficacy: Adipose-derived MSCs (AD-MSCs) and umbilical cord-derived MSCs (UC-MSCs) showed remarkable improvements in various knee function and pain scores. - Safety: While AD-MSCs were highly effective, they had a higher incidence of adverse events compared to placebo treatments. Impact on Clinical Practice: - Enhanced Treatment Options: This study confirms the effectiveness of MSCs, especially AD-MSCs and UC-MSCs, in treating KOA. Incorporating these therapies can significantly improve patient outcomes in terms of pain relief and knee function. - Incorporation into Treatment Protocols: MSC therapies can be integrated into existing treatment plans, providing a comprehensive approach alongside physical therapy and pharmacological treatments. - Potential to Delay or Avoid Surgery: Leveraging MSCs could enhance the quality of life for KOA patients, potentially delaying or avoiding the need for more invasive treatments like surgery. This study provides a robust framework for integrating MSC therapies into clinical practice, offering a promising avenue for advancing the treatment of knee osteoarthritis in orthopedic regenerative medicine. #Orthopedics #RegenerativeMedicine #KneeOsteoarthritis #StemCellTherapy #ClinicalResearch #PatientCare

NEW safety study on QuadLink ACLR with InternalBrace! This study sought to investigate whether incorporating an InternalBrace (IB) in an all–soft tissue quad tendon autograft (QT) ACLR leads to satisfactory patient outcomes while having no intra-articular side effects as determined by MRI. All patients had at least 2-year follow up. Key Takeaways: ? The most important finding was that the prospective MRI data—at median time from surgery to MRI of 24 months—showed that augmenting QT ACLR with IB led to similar graft signal intensities and Howell scores previously described for grafts with no IB?with most patients demonstrating little to no synovitis.? ? This suggests that STA does not interfere with the ligamentization process, lead to objective differences seen within the graft, or incite a significant intra-articular inflammatory response ? QT ACLR with IB did not demonstrate adverse intra-articular changes on MRI. None of the patients in the present study exhibited any signs of premature arthritic changes on their 2-year follow-up compared with their preoperative radiographs ? Although the present study lacked a control group to compare with, the PROM scores were at least comparable to those that have already been studied in the literature. #internalbrace #aclreconstruction #aclr #kneeligamentinjury #sportsmedicine #helpingsurgeonstreattheirpatientsbetter American Academy of Orthopaedic Surgeons (AAOS) The International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) ESSKA - European Society of Sports Traumatology, Knee Surgery & Arthroscopy Arthroscopy Association of North America Arthrex

Another interesting article focuses on the impact of kinesiophobia on postoperative rehabilitation outcomes in patients with spinal disorders. According to the findings, there is a high incidence of kinesiophobia following surgery, which may result in a challenge to the rehabilitation process, affecting patients' level of participation in exercises and their ability to recover fully from surgery. Several papers published by our team have demonstrated that fear avoidance and demoralization directly correlate with the deterioration of gait and balance. Therefore, we keep collecting this outcome as part of our standard of care. Linke to our papers: https://lnkd.in/e9TE3JR4 https://lnkd.in/ecMMy-pS https://lnkd.in/ej9UdKeY https://lnkd.in/gn3RsiuE #kinesiophobia Journal of Orthopaedic Surgery and Research Fujian Medical University, Cervical Spine Research Society Orthopaedic Research Society American Academy of Orthopaedic Surgeons (AAOS) https://lnkd.in/gEbPyA9E

Platelet-rich plasma, arthroscopic partial meniscectomy for degenerative meniscus tear, hip arthroscopy for degenerative joint disease, treatment of degenerative root tear and numerous other procedures in #orthopaedics are low-value and not backed by high-quality evidence. Still, they are commonly done. My esteemed colleague Teemu Karjalainen wrote an excellent editorial in the Finnish Medical Journal and I decided to translate it and publish it in my blog. This editorial nicely encapsulates the major problems we are facing in the orthopaedic surgery and science. #ebm #EvidenceBasedOrthopaedics #LowValueCare

“[Joint preservation] is an opportunity for us to take advantage of early diagnosis, to intervene in the process of degeneration of a joint at an early time point when it can be altered and change the natural history of the disease, so that we prevent or delay the onset of arthritis,” Benjamin Domb told Healio. In the October edition of Healio | Orthopedics Today, I spoke with Benjamin Domb, Michael Alaia, Ernest Sink, MD, Rafael J. Sierra, MD, and Brett Crist about #jointpreservation techniques for #endstagearthritis. Read the full story here: https://lnkd.in/eui7fCHp

We are glad to share a rare case published in SVOA Orthopaedics. Title: Osteomyelitis of the Ischium in a Hemodialysis Dependent Adult – A Rare Case Report (DOI: 10.58624/SVOAOR.2023.03.057) Authors: Dr. Rosana Pinheiro and team Case Report: A 71-year-old woman, with end stage renal disease on hemodialysis, presented in orthopedic emergency department for purulent drainage of a right buttock swelling, which had months of insidious evolution. She only had sustained fever for a week of evolution. The malaise and asthenia were common symptoms for this patient between hemodialysis sessions, so she didn’t value those symptoms. Explore complete case here: https://lnkd.in/gYegZPRE You can reach out SVOA Orthopaedics for publications at [email protected] #orthopaedics #openaccess #casereport #traumatology #svoaorthopaedics #orthopaedicsurgery