Insilicom的动态

Kicking off from an excellent collaboration with Prof. David Hunter and Xiaoqian Liu, we're excited to share our latest publication comparing #placebo responses in internet-based versus onsite randomized controlled trials (RCTs) for hand osteoarthritis. ?? The study revealed no significant differences in placebo responses between the two study settings. Additionally, with the support of Placebell's digital solution, we found no differences in placebo response predictors, underscoring the reliability and efficacy of internet-based RCTs. This breakthrough paves the way for remote trials as a viable alternative and has the potential to enhance patient diversity and inclusion in clinical research. Learn more about the potential of internet RCTs in medical research → https://bit.ly/4bd0g7q

?? I am pleased to announce that our manuscript, "A Newly Developed Method for Assessing Co-Exposure to Free Dose Combinations: A Proof-of-Concept Study using Antihypertensive Medications in Danish Registers," has been accepted for publication in Aging Clinical and Experimental Research (Impact Factor: 3.5). In this study, we developed and shared a set of R functions designed to compute treatment episodes reflecting co-exposure to multiple medications over a follow-up period. We applied this method specifically to antihypertensive medications within Danish registers, providing an overview of the most frequently co-prescribed combinations in Denmark over the past 20 years. This approach addresses key methodological biases seen in prior methods, including conditioning on future events, healthy adherer bias, and immortal time bias.

ORAU is proud to announce the recent award from the National Institutes of Health (NIH) to establish a state-of-the-art training center as one of five major centers for the Common Fund Data Ecosystem (CFDE). NIH Common Fund programs generate a wide range of diverse and valuable data sets and knowledge designed to be used by the research community. The CFDE aims to facilitate improved discovery, reuse, integration, and analyses of these datasets to form novel hypothesis for accelerating discoveries in biomedical research. Click the link to learn more ?? ?? ?? https://bit.ly/4gj771t #FurtherTogether

"Efficacy of water filters and training interventions in mitigating gastrointestinal symptoms in rural Honduras." A group of current pre-health students collaborated with Dr. Colin Swearingen from the Political Science Department at John Carroll University on a recently published article. The article examines the efficacy of water filters in rural Honduras. During their time in Honduras, the students assisted with data collection and conducted five free medical clinics. Naya '25 remarked, "We were so moved by our experiences that we chose to take action through this project.” Congratulations on this publication, which is a true reflection of the JCU mission. Access the full article here: https://lnkd.in/gacAKU5u

?? Call for papers ?? ?? Special Issue "Recent Advancements and Challenges in Cardiac Arrhythmias: Part II" edited by Dr. Nesti and Dr. Sciarra ??Website and submission link: https://lnkd.in/gJHejynZ ??In this Special Issue, we will focus on recent advancements and challenges in cardiac arrhythmias. Welcome your submissions! ?? Deadline for manuscript submissions: 31 December 2024 #digestive Arrhythmias Martina Nesti Journal of Clinical Medicine (JCM) MDPI

INMHA is excited to partner with the Canadian Association for Neuroscience for this year’s competition to award $1,500 to 15 trainees who published research relevant to INMHA’s mandate in 2024. Learn more about specific eligibility requirements and how to apply for the competition: https://lnkd.in/gF4XMZTS Canadian Institutes of Health Research | Instituts de recherche en santé du Canada

**Exploring the Future of Precision Medicine with Dr. Mark Kristiansen ** This is a secret I have kept for a while ?????? I had the privilege of interviewing Dr. Mark Kristiansen, the Head of Genomics at the Zayed Centre for Research into Rare Disease in Children (ZCR), UCL half a year ago, during which we delved into the future of precision medicine, its challenges, and how we can address them. In our discussion, Dr. Kristiansen emphasized the importance of public engagement in personalized medicine - the need for transparency and openness in scientific work, which is embodied in the 'fish tank' design of the ZCR lab. He also touched on the challenges posed by the diverse nature of personalized medicine and the danger of false information, stressing the importance of truthful communication to maintain public trust and the need for a tailored education strategy in different contexts. Lastly, he underscored the role of healthcare providers in informing patients about novel therapies and the need for government involvement in integrating personalized medicine into traditional clinical trials and approval systems. Nevertheless, we both agreed that the future of personalised medicine is optimistic, but the road to a better future is always an uphill climb. I would like to express my gratitude to Dr. Mark Kristiansen for his insightful thoughts and to the editor for making this article possible. You can now view my article on https://lnkd.in/g7j3ydjJ #PrecisionMedicine #Genomics #HealthcareInnovation #PublicEngagement

Check out Weill Cornell Medicine's first annual Cores Day on 01/14! PacBio is proud to be a technology partner supporting the WCM research community. There are opportunities for attendees to save on services. Don't miss out! Here are a few examples of what you can achieve on the Revio system at WCM: HiFi WGS with 5mC, 500ng input, 120Gb HiFi yield; Full-length cDNA sequencing, bulk or single-cell: a fuller picture of the transcriptome; Best-in-class and cost-effective solution for microbial sequencing, whether it's for isolates, communities, or 16S/ITS amplicons. See agenda and participating cores: https://lnkd.in/e44wms8d

“????? ?????????? ?????? ????????? ???????? ??????????? ?????????? ???????” With gratitude and humility, I’m pleased to share that my paper, titled “The Impact of Brain Tumors on Emotional and Behavioral Functioning” has been published in Cureus Journal of Medical Science . This paper delves into the complex interplay between brain tumors and their effects on emotional and behavioral functioning, shedding light on an often-overlooked aspect of patient care. By highlighting key findings and current perspectives, I aim to contribute to a deeper understanding of this complex relationship. I invite you to read the paper and engage in the discussion. Your reflections and insights are always welcome as we strive for continuous growth in medical knowledge and practice. ?? Read the full paper here: https://lnkd.in/ehnfUPVG I look forward to your feedback and discussions! DOI: 10.7759/cureus.75315

The ICTS has awarded five awards to investigators in the ICTS’ 3rd annual virtual poster display and contest. As part of the 6th Annual ICTS Symposium, 24 separate posters were submitted and reviewed by 10 ICTS faculty. Posters showcased one of these 4 types of translational research: Posters were also categorized by early-stage, clinical, or or health services/population health research. Each poster was evaluated by three reviewers and judged in areas of significance, approach, innovation, visual presentation, and for long-term, short-term, national, and local impact. Learn more > https://lnkd.in/gYUgwXqy