Ines Godart的动态

Discover how our AI technology is revolutionizing cancer treatment at Aichi Cancer Center. By analyzing over 1.2 million medical records, we're identifying effective drug candidates for specific gene mutations. Learn how this partnership enhances patient care: https://okt.to/ovrpL6 #HealthyLiving #AI #CancerTreatment #Healthcare #Fujitsu #FujitsuPortugal

Gene choice in cancer cells is exclusive in ion transport but concurrent in DNA replication. Read the article here: https://lnkd.in/d-mxD59z

Jan 2024 StemCell Express: Riding the Rails of Progress in Cancer Therapy! The field of cancer therapy is undergoing transformative changes, driven by the following trends: iPSC-derived MSCs, MSCs-derived EVs, and Cas9-mediated gene editing in MSCs. iPSC-derived MSCs offer a scalable and standardised cell source, overcoming limitations associated with traditional harvesting methods. MSCs-derived EVs emerge as a promising cell-free therapeutic tool, exhibiting targeted drug delivery capabilities and lower immunogenicity. Meanwhile, Cas9-mediated gene editing empowers precise control over MSC behaviour, enhancing their therapeutic efficiency. Together, these innovations propel the field forward, opening avenues for personalised, effective, and safer cancer treatments. StemCell Express is truly riding the rails of progress, bringing hope for a brighter future in the fight against cancer. #stemcelltherapy #cancertreatment #cancertherapy

??CAR-T cell therapy is a ground-breaking and highly effective personalized treatment involving T cells from a patient's immune system, which are genetically engineered to target and destroy cancer cells. While CAR-T cell therapy has shown remarkable clinical success in treating specific blood cancers, and now autoimmune diseases, current manufacturing processes have significant room for improvement. ?? Read our last article on Cell & Gene Therapy Insights, written with my colleagues Narjes Armanet. A warm acknowledgement as well to my college Yi SHANG for all her valuable inputs ?? # Qualitycontrol #wearebiomérieux

??What is the Oncotype test? The Oncotype DX test is a type of gene expression test for breast cancer that helps doctors learn more about the chances of cancer recurring and determines if you may get an added benefit from chemotherapy as part of your treatment plan. (Some cases include radiation treatment.) ~The Oncotype DX test uses genetic material from cancer cells to predict how likely breast cancer will recur after treatment and guide treatment decisions. It essentially answers the question: What are the genes in my cancer cells doing and why? This way, you can put up an informed fight. ~In general, this process of gene expression profiling identifies patterns in the genetic material of cancer cells to make predictions about how they may behave. This information may lead to more personalized treatment. ~If the breast cancer you have doesn't fit the criteria for the Oncotype DX test, there may be another type of gene expression test that your cancer care team may use to guide treatment recommendations. . #breastcancerawareness #breastcancerhealth #breastcancereducation #breastcancersurvivors #breastcancersupport #breastcancerdiagnosis #breastcancerstage1 #breastcancerstage2 #doublemasectomy #metastaticbreastcancer #breastcancerwellness #faiththroughfire

?? CAR-T cell therapy is a ground-breaking and highly effective personalized treatment involving T?cells from a patient’s immune system, which are genetically engineered to target and destroy cancer cells. While CAR-T?cell therapy has shown remarkable clinical success in treating specific blood cancers, current manufacturing processes have significant room for improvement. ?? Read the complete piece on Cell & Gene Therapy Insights, written by my colleagues Narjes Armanet and Felix Montero Julian ?? #WeArebioMérieux #CellandGeneTherapy

In oncology, RNA plays crucial roles in understanding cancer biology, diagnosis, prognosis, and treatment. Researchers study RNA to identify genetic mutations, gene expression patterns, and molecular signatures associated with different types of cancer. Techniques like RNA sequencing allow for the comprehensive analysis of RNA molecules, providing insights into cancer progression and response to therapy. Additionally, RNA-based therapies, such as RNA interference (RNAi) and RNA-based vaccines, hold promise for targeted cancer treatments by modulating gene expression or boosting the immune response against cancer cells.

ERRγ and lung cancer Metastasis remains the leading cause of mortality in patients with small cell lung cancer (SCLC). Through single-cell, bulk transcriptome analysis and gene functional studies, estrogen-related receptor gamma (ERRγ) was identified as a key player of extracellular matrix (ECM) remodelling and a promising target for metastatic SCLC. The researchers show that ERRγ was overexpressed in metastatic SCLC tumors and positively correlated with disease progression. They also identified ERRγ as a key determinant of ECM-related gene expression in SCLC cells. Genetic and pharmacological suppression of ERRγ reduced collagen production, cell-matrix adhesion, and suppressed microfilament formation, thereby halting SCLC cell invasion and metastatic dissemination. In addition, ERRγ antagonists suppressed SCLC tumor growth and metastasis, and restored the sensitivity of resistant SCLC to chemotherapy. #sciencenewshighlights #ScienceMission https://lnkd.in/eJJshmdt https://lnkd.in/ePAx7Y_q

?? Revolutionizing Cancer Treatment with Genomic Medicine A significant milestone has been reached in the field of genomic medicine as the FDA approves vorasidenib, a new drug designed to target IDH gene mutations in brain cancer. This approval follows a successful phase 3 clinical trial demonstrating improved progression-free survival in patients with IDH-mutant gliomas. The findings emphasize the impact of genetic research in developing precision therapies tailored to the genetic profile of individual cancers. Such advancements not only improve patient outcomes but also pave the way for future research into other types of brain cancer. Read the full article here: Medical Xpress ?? #PrecisionMedicine #Genomics #CancerTreatment #Innovation #MedicalResearch #BrainCancer #Healthcare

?? CAR-T cell therapy is a ground-breaking and highly effective personalized treatment involving T?cells from a patient’s immune system, which are genetically engineered to target and destroy cancer cells. While CAR-T?cell therapy has shown remarkable clinical success in treating specific blood cancers, current manufacturing processes have significant room for improvement. ?? Learn all about it in Cell & Gene Therapy Insights, written by Narjes Armanet, MD, PhD and Félix A MONTERO-JULIAN PhD ?? #celltherapy #cellandgenetherapy