Patients with a small annulus in the aortic valve of the heart – the ring-like base of the valve that supports its leaflets – face challenges when undergoing transcatheter aortic valve replacement (TAVR). These patients, many of them women, are at greater risk for a host of poor outcomes.
Now, the?largest, randomized, controlled TAVR trial to primarily enroll women has some answers to address this.?Results of the SMART trial, comparing self-expanding and balloon-expandable TAVR valves in patients with a small annulus, were recently published in the?New England Journal of Medicine, with UH Harrington Heart & Vascular Institute’s?Guilherme Attizzani, MD,?Interventional Director of?the Valve and Structural Heart Disease Center, as study co-author and steering committee member.
Dr. Attizzani also holds the Alexander and Marianna McAfee Endowed Chair in Innovative Cardiovascular Intervention.
SMART trial results show advantages for the self-expanding valve – already in regular use at UH for patients with a small annulus. But Dr. Attizzani says the study is likely to have wide impact elsewhere and cause clinicians?who haven’t typically used these devices to take a second look.
Read more at https://lnkd.in/gzz42n9v
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VP, Strategic Partnerships- Flourish Research
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