Creyon Bio的动态

For ion channel researchers there is a great new resource available online and soon to be in print. The Ion Channels as Targets in Drug Discovery book (Springer), within which is our chapter on tools and therapeutics from venoms and toxins. Figure 1 has a handy map and overview of the types of targets with toxin ligands that we know of so far. So if you have an ion channel target and your chemistry is not generating the hits you need, maybe you should try venoms and toxins. read more here - https://lnkd.in/eq4NcMXG

??The excitement is great and preparations are ongoing - the #IOPC2024 will be a very special event. This is why... ??The peptide therapeutics landscape is changing dramatically. Not only due to the success of obesity treatments with GLP-1 analogs, but also due to fading boundaries to other modalities like oligonucleotides. The associated challenges for synthesis, in particular, are immense and, in order for us to help overcome them, conferences like IOPC are fundamental to engage with the scientists and understand their needs. ???? ???? ??We have prepared for this event with a set of new application data and we are happy to share this in advance: https://lnkd.in/dyrPC82T ??Please meet our team including Luísa Aguiar and Silvia Marini at booth #16 to discuss your project and how PurePep solutions can help you innovate for a better life. #purepep #oligonucleotide #peptides #synthesis #purification

Save the date for the next #MedChemCASES

?? Five hours to go! ?? Don't miss today's session in our Drug Discovery Webinar Series: "Covalent Fragment Screening and its Reemerging Promise in Drug Discovery" Covalent inhibitors have reemerged as a hot topic in drug discovery research. During this webinar, we will discuss our approach to identifying high quality covalent fragment hits. This will include curation of our diverse covalent fragment library, covalent fragment screening by intact mass spectrometry, assessment of warhead reactivity with glutathione (GSH), confirmation of the fragment binding site by peptide mapping and generation of Ki/kinact values by LC-MS. Be sure to join us and take advantage of the live Q&A with two experts in the field! ?? Date: Monday, 9th December 2024 ?? Time: 14:00-15:00 GMT ?? Register now for FREE: https://lnkd.in/e9bA7JS4

Interested in #EVs based research? ?? This webinar might be of interest! Today!! #ExtracellularVesicles #EVResearch #InnovativeTherapies #TargetedDrugDelivery #BiotechInnovation #ExosomeResearch #Vesiculab #KarolinskaInstitute #ScientificWebinar #EVTechnologies #DrugDeliverySolutions #ResearchTools #EVAnalysis #Biopharma #BiotechSolutions #TherapeuticAdvancements #EVApplications

Did You Know that Bio-Rad Can Help You Choose a Mycoplasma Detection Strategy? Learn more about at https://lnkd.in/g8zbzW3y Mycoplasma contamination in cell culture can derail a successful biopharma project, but choosing an approach for mycoplasma detection can be a challenge. Bio-Rad is here to help! Check out this video for some key considerations in choosing a mycoplasma detection strategy that fits your needs. #Biopharma #ddPCR #Mycoplasma

Did You Know that Bio-Rad Can Help You Choose a Mycoplasma Detection Strategy? Learn more about at https://lnkd.in/g8zbzW3y #Biopharma #ddPCR #Mycoplasma

Trying to find the right receptor ligand binding assay for your lead optimization? Download our handy guide to explore the range of receptor ligand binding assays that Gifford Bioscience offer. Our interactive table covers the outcome for each technique, its suitability for your sample type and the pros and cons. If you need more help selecting the right assay, our expert scientists can offer their advice and guidance on our range of complex and niche assays. Speak directly to one of our PhD scientists from day one and partner with the specialists in receptor ligand binding assays. For interactive mode, expand to full screen and click on "Accessibility Mode", top right. #receptorpharmacology #drugdiscovery #pharmacology

?? Exciting advancements in oligonucleotide therapeutics! Check out our latest application note on the comprehensive characterization and monitoring of oligonucleotide impurities using Thermo Fisher Scientific's Orbitrap Exploris 240 LC-HRAM-MS platform. ?? Learn how BioPharma Finder 5.1 software and Chromeleon CDS 7.3.1 enable precise sequence confirmation, modification localization, and impurity quantitation with unmatched clarity and efficiency. ?? Accelerate your research and ensure regulatory compliance with cutting-edge solutions designed for the intricate analysis of therapeutic oligonucleotides. Learn more at https://spr.ly/6046xXNSg #Biopharma #Oligonucleotides #MassSpectrometry #ThermoFisherScientific https://spr.ly/6047xXNS9

??Discover the importance of looking at torsional data to guide your drug design journey. Get inspired by the conformational studies performed by Gilles Ouvry, VP of Chemistry at NRG Therapeutics, and learn how to mine the CSD to identify the most likely torsions in your molecule of interest. ??https://lnkd.in/eSh4QASX #Crystallography #DrugDesign