?? Join Our Team as a Translational Scientist in Clinical-Stage Biotech Are you a highly motivated, hands-on Translational Scientist ready to transform cancer treatment through antibody therapeutics? We’re seeking an experienced professional to lead our biomarker programs using advanced technologies like NGS and spatial transcriptomics. This onsite position in Brighton, MA, reports directly to our VP and Head of Translational Science. Make your science count. Learn more and apply now: cmpx.info/job. #BiotechJobs #BostonBiotech
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I successfully completed my undergraduate project in college. Project Title: "Integration of Network Pharmacology and In-Silico Studies to Evaluate Phytoconstituents for NSCLC Treatment." Description: Conducted an in-depth evaluation of the anti-tumor effects of phytoconstituents (Nimbolide, Piperine, and Procyanidin B2) on non-small cell lung cancer (NSCLC) cell lines. Utilized various computational tools and methods including SwissTarget Prediction, GeneCards, Cytoscape, STRING, KEGG pathway enrichment, SwissADME, ProTox-II, and molecular docking studies to identify potential therapeutic targets and assess drug properties. Contributions: - Identified key targets and pathways for NSCLC treatment through network pharmacology. - Performed molecular docking to evaluate binding affinities to targets such as EGFR, CDK4, ERBB2, HSP90AA1, and RHOA. - Assessed drug-likeness and toxicity properties to determine the therapeutic potential of selected phytoconstituents. Technologies Used: SwissTarget Prediction, GeneCards, Cytoscape, STRING, DAVID, SwissADME, ProTox-II, Molegro Virtual Docker.
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???????? ?????? ?????? ?????? ???????????????? ???? ?????????????? ?????????????????????????????? ???? ???????????? ????????????????? Spatial transcriptomics offers key benefits in cancer research by enabling high-resolution mapping of gene expression within tissue samples, preserving spatial context. This technology allows researchers to identify the heterogeneity of tumors, uncovering distinct cellular environments and interactions that drive cancer progression. By providing a comprehensive view of the tumor microenvironment, spatial transcriptomics aids in identifying novel biomarkers and therapeutic targets. It also enhances our understanding of tumor evolution, drug resistance, and metastasis. Overall, spatial transcriptomics accelerates the development of personalized cancer treatments, leading to more effective and targeted therapies for patients. ???? ???????? ???????????? ?????????? ?????? ???????????? ???? ?????????????? ?????????????????????????????? ????????????. ?????????????? ?????? ???????????? ??????: https://lnkd.in/dPZKtDRb *???? ??????????????: Consumables, Instruments, Services *???? ??????????????????????:?Clinical, Drug and Biomarker Discovery and Development *???? ?????? ????????: Academic Institutes, Clinical and Life Science Laboratories, Pharmaceutical and Biotechnology Companies, Others *???? ????????????: North America, Europe, Asia-Pacific, South America, Middle East & Africa *???? ?????? ??????????????: 10x Genomics, NanoString Technologies, Inc., Akoya Biosciences, Inc., Bio-Techne, Bruker, Standard BioTools, Vizgen #spatialtranscriptomics #genomics #biotechnology #molecularbiology #singlecellanalysis #genomicresearch #biomedicalresearch #nextgenerationsequencing #transcriptomics #geneexpression #tissueanalysis #cellbiology #precisionmedicine #cancerresearch #neuroscience #bioinformatics #biotech #geneticresearch #healthcareinnovation #researchanddevelopment #lifesciences #biomedicalscience #clinicalresearch #drugdiscovery #healthtech #moleculardiagnostics #personalizedmedicine #biotechresearch #medicalinnovation #spatialgenomics
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???????? ?????? ?????? ?????? ???????????????? ???? ?????????????? ?????????????????????????????? ???? ???????????? ????????????????? Spatial transcriptomics offers key benefits in cancer research by enabling high-resolution mapping of gene expression within tissue samples, preserving spatial context. This technology allows researchers to identify the heterogeneity of tumors, uncovering distinct cellular environments and interactions that drive cancer progression. By providing a comprehensive view of the tumor microenvironment, spatial transcriptomics aids in identifying novel biomarkers and therapeutic targets. It also enhances our understanding of tumor evolution, drug resistance, and metastasis. Overall, spatial transcriptomics accelerates the development of personalized cancer treatments, leading to more effective and targeted therapies for patients. ???? ???????? ???????????? ?????????? ?????? ???????????? ???? ?????????????? ?????????????????????????????? ????????????. ?????????????? ?????? ???????????? ??????: https://lnkd.in/dPZKtDRb *???? ??????????????: Consumables, Instruments, Services *???? ??????????????????????:?Clinical, Drug and Biomarker Discovery and Development *???? ?????? ????????: Academic Institutes, Clinical and Life Science Laboratories, Pharmaceutical and Biotechnology Companies, Others *???? ????????????: North America, Europe, Asia-Pacific, South America, Middle East & Africa *???? ?????? ??????????????: 10x Genomics, NanoString Technologies, Inc., Akoya Biosciences, Inc., Bio-Techne, Bruker, Standard BioTools, Vizgen #spatialtranscriptomics #genomics #biotechnology #molecularbiology #singlecellanalysis #genomicresearch #biomedicalresearch #nextgenerationsequencing #transcriptomics #geneexpression #tissueanalysis #cellbiology #precisionmedicine #cancerresearch #neuroscience #bioinformatics #biotech #geneticresearch #healthcareinnovation #researchanddevelopment #lifesciences #biomedicalscience #clinicalresearch #drugdiscovery #healthtech #moleculardiagnostics #personalizedmedicine #biotechresearch #medicalinnovation #spatialgenomics
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???????? ?????? ?????? ?????? ???????????????? ???? ?????????????? ?????????????????????????????? ???? ???????????? ????????????????? Spatial transcriptomics offers key benefits in cancer research by enabling high-resolution mapping of gene expression within tissue samples, preserving spatial context. This technology allows researchers to identify the heterogeneity of tumors, uncovering distinct cellular environments and interactions that drive cancer progression. By providing a comprehensive view of the tumor microenvironment, spatial transcriptomics aids in identifying novel biomarkers and therapeutic targets. It also enhances our understanding of tumor evolution, drug resistance, and metastasis. Overall, spatial transcriptomics accelerates the development of personalized cancer treatments, leading to more effective and targeted therapies for patients. ???? ???????? ???????????? ?????????? ?????? ???????????? ???? ?????????????? ?????????????????????????????? ????????????. ?????????????? ?????? ???????????? ??????: https://lnkd.in/dPZKtDRb *???? ??????????????: Consumables, Instruments, Services *???? ??????????????????????:?Clinical, Drug and Biomarker Discovery and Development *???? ?????? ????????: Academic Institutes, Clinical and Life Science Laboratories, Pharmaceutical and Biotechnology Companies, Others *???? ????????????: North America, Europe, Asia-Pacific, South America, Middle East & Africa *???? ?????? ??????????????: 10x Genomics, NanoString Technologies, Inc., Akoya Biosciences, Inc., Bio-Techne, Bruker, Standard BioTools, Vizgen #spatialtranscriptomics #genomics #biotechnology #molecularbiology #singlecellanalysis #genomicresearch #biomedicalresearch #nextgenerationsequencing #transcriptomics #geneexpression #tissueanalysis #cellbiology #precisionmedicine #cancerresearch #neuroscience #bioinformatics #biotech #geneticresearch #healthcareinnovation #researchanddevelopment #lifesciences #biomedicalscience #clinicalresearch #drugdiscovery #healthtech #moleculardiagnostics #personalizedmedicine #biotechresearch #medicalinnovation #spatialgenomics
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?? Meet Radar Therapeutics: an innovative leader in genetic medicine and winner of the WACKER Biotech Discovery Award! Its platform for selectively activated mRNAs can precisely control the expression and activity of genetic medicines at the cell type or even cell state level, thereby revolutionizing treatment for a broad array of autoimmune, oncological, and rare diseases. Co-founded by Sophia Lugo, MS, MBA and Dr. Eerik Kaseniit, PhD, Radar Therapeutics emerged from Stanford University and MIT as a pioneering venture that addresses the limitations in current cell and gene therapies—high costs, scalability challenges, and safety risks. As the Wacker Biotech Discovery Awardee, Radar will receive in-kind credits to work with the experienced team at Wacker to develop its advanced therapeutics and advance its mission of accessible genetic medicine for all. Reflecting on her journey, Sophia shared, "I have always been passionate about equitable access to healthcare and innovation. We should innovate with all patients of all backgrounds in mind. I committed my career to solving critical problems and was fortunate to meet Dr. Eerik Kaseniit, a brilliant bioengineer who invented the foundational technology behind RADAR while at Stanford." With backing from leading VCs and pharma, Radar is on a mission to revolutionize programmable medicines. Come meet them at the CLS Innovation Showcase on Dec 10. ?? For more information about the contract development and manufacturing services of Wacker Biotech, please visit https://bit.ly/3AAiKRU and to learn more about Radar Therapeutics and their impact visit https://bit.ly/48vBfDG. #GeneTherapy #LifeSciences #HealthcareInnovation #SyntheticBiology #EquitableHealthcare #CALifeSciences
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Are you passionate about using cutting edge single cell technologies to identify targets for various autoimmune diseases? Jessica Marbourg, PhD is looking for someone to join our experimental team on single cell biology (scRNAseq, CITEseq, scATACseq, etc) and be part of an interdisciplinary team. The role will provide you with ample opportunities to diversify your expertise in experimental innovation, interdisciplinary collaborations, drug discovery, and autoimmune biology. https://lnkd.in/eCbCJS2z #abbvie #singlecell #transcriptomics #epigenomics #immunology
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A Complete Guide for ???????????????? ???????????????????? ?????? ???????????????? - [PDF Guide] ? ?????????? ???????? ?????? ??????>> https://lnkd.in/dv5MvvD7 Research antibodies are crucial for research in several fields, including oncology, infectious diseases, #cardiology, #immunology, neurology, and stem cell research. Antibodies help in #protein identification and detection, which can be associated with specific #diseases. Furthermore, antibodies are also used in the identification of novel biomarkers which help in disease diagnosis. The research antibodies and reagents market is driven by the rising #proteomics and #genomics research studies, increase in research funding, increasing R&D investments by #pharmaceutical & #biotechnology companies, and the growing industry-academia collaboration. However, the high cost and time for the identification and development of potential antibodies hinder the growth of this market. ? ?????????????? 1.??????Rising Proteomics and Genomics Research Studies 2.??????Increase in Research Funding 3.??????Growing Industry-Academia Collaboration 4.??????Increasing R&D Investments by Pharmaceutical & Biotechnology Companies ? ???????????????????? 1.??????????Western Blot 2.??????????Immunofluorescence 3.??????????Enzyme-Linked Immunosorbent Assay 4.??????????Multiplex Immunosorbent Assay 5.??????????Flow Cytometry 6.??????????Immunohistochemistry 7.??????????Immunoprecipitation (IP) 8.??????????Others #Keyplayers : Merck KGaA (Germany), Thermo Fisher Scientific Inc. (U.S.), F. Hoffmann La-Roche AG (Switzerland), Agilent Technologies, Inc. (U.S.), Becton, Dickinson and Company (U.S.), PerkinElmer, Inc. (U.S.), GenScript Biotech Corporation (U.S.), Bio-Techne Corporation (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Santa Cruz Biotechnology, Inc. (U.S.) ? #ResearchAntibodies #antibodies #reagents #oncology #neurology #elisa #westernblotting #pharma #academia #healthcare #laboratory #diseases #antibody #medicaldevices #medical
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Neurogene Inc., a gene therapy developer focused on rare neurological diseases, has secured $200 million through a private funding deal that will extend its cash reserves into late 2027. The company on Monday?signed an agreement?to raise the funds in a so-called PIPE financing, a deal in which publicly traded entity sells shares to private investors in a specially negotiated transaction. More than half a dozen investment firms, including RTW Investments, LP , EcoR1 Capital, LLC and Samsara BioCapital, are involved. They’ll acquire just over 1.8 million shares of common stock at $50 apiece, and pre-funded warrants to buy another roughly 2.2 million shares at about the same price. #privatefunding #funding #biotech #biotechnology #genetherapy #200m #advancedtherapies #regenerativemedicine #PIPEfinancing #lifesciences #neurologicaldiseases #neuro #extendrunway #Rettsyndrome #Battendisease #raredisease #clinicaldata #readout
Neurogene secures $200M ahead of anticipated study readout
biopharmadive.com
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A Complete Guide for ???????????????? ???????????????????? ?????? ???????????????? - [PDF Guide] ? ?????????? ???????? ?????? ??????>> https://lnkd.in/drNrZSzP Research antibodies are crucial for research in several fields, including oncology, infectious diseases, #cardiology, #immunology, neurology, and stem cell research. Antibodies help in #protein identification and detection, which can be associated with specific #diseases. Furthermore, antibodies are also used in the identification of novel biomarkers which help in disease diagnosis. The research antibodies and reagents market is driven by the rising #proteomics and #genomics research studies, increase in research funding, increasing R&D investments by #pharmaceutical & #biotechnology companies, and the growing industry-academia collaboration. However, the high cost and time for the identification and development of potential antibodies hinder the growth of this market. ? ?????????????? 1.??????Rising Proteomics and Genomics Research Studies 2.??????Increase in Research Funding 3.??????Growing Industry-Academia Collaboration 4.??????Increasing R&D Investments by Pharmaceutical & Biotechnology Companies ? ???????????????????? 1.??????????Western Blot 2.??????????Immunofluorescence 3.??????????Enzyme-Linked Immunosorbent Assay 4.??????????Multiplex Immunosorbent Assay 5.??????????Flow Cytometry 6.??????????Immunohistochemistry 7.??????????Immunoprecipitation (IP) 8.??????????Others ? 10 ?????????????? ?????????????????? ???? ?????? ???????????>> https://lnkd.in/d9JSzCZM?? #Keyplayers : Merck KGaA (Germany), Thermo Fisher Scientific Inc. (U.S.), F. Hoffmann La-Roche AG (Switzerland), Agilent Technologies, Inc. (U.S.), Becton, Dickinson and Company (U.S.), PerkinElmer, Inc. (U.S.), GenScript Biotech Corporation (U.S.), Bio-Techne Corporation (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Santa Cruz Biotechnology, Inc. (U.S.) ? #ResearchAntibodies #antibodies #reagents #oncology #neurology #elisa #westernblotting #pharma #academia #healthcare #laboratory #diseases #antibody #medicaldevices #medical
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