COEPTIS, Inc的动态

FibroBiologics is set to join the Russell 2000? Index effective July 1, 2024, according to a preliminary list of additions. This milestone reflects our growth and commitment to developing novel therapeutics using fibroblasts. Joining the #Russell2000 marks a significant step in increasing our visibility in the investment community and enhancing shareholder value. For more: https://bit.ly/4cHC6ST #Biotechnology #InvestmentGrowth

Learn about robust #bioanalysis methods for oligo therapeutics. View our NEW infographic showing how Gyrolab automated oligo quantification assays work for PK/TK bioanalysis. Check out our feature with Bioanalysis Zone https://lnkd.in/ejVWFUtS

Producing engineered extracellular vesicles for therapeutics applications: in this study, Kristin Luther, Joe Nabhan at Vesigen Therapeutics, Inc. and collaborators evaluated two scalable strategies for generating GFP-loaded ARMM-engineered EVs: transient transfection and stable cell line-based production. The upstream ARMM production processes used a suspension HEK293-derived line called 5B8 from Lonza, with production assessed in both shake flasks and bioreactors. For downstream ARMM purification, they employed Tangential Flow Filtration and Anion Exchange Chromatography https://lnkd.in/eWs8TfSM In vivo, ARMMs demonstrated rapid biodistribution, primarily to the spleen and liver, with lesser distribution to the kidneys and lungs. The successful scale-up of ARMM production highlights the potential of engineered EVs. An article also authored by Ali Navaei, Leah Gens, Carson Semple, Pearl Moharil, Ilaria Passalacqua, Komal Vyas, Qiyu Wang, Shu-Lin Liu, Lucy Sun, Senthil Ramaswamy and Davide Zocco #extracellularvesicles #exosomes #bioengineering #translationalmedicine #cellculture #Vesiculab

Longitude portfolio company Vera Therapeutics, Inc. has shown the effect of atacicept on kidney function in patients with immunoglobulin A nephropathy (IgAN) persists out to 96 weeks. The durability of the effects seen in the phase 2b trial led Evercore ISI analysts to say “this feels like a ‘functional cure’," reports Nick Paul Taylor in Fierce Biotech. Read more about atacicept's data at https://lnkd.in/eVZxWxdz #Biotech

#DYK: ~75% of disease-causing targets are located inside cells and most are still considered inaccessible? We believe we have discovered the solution to the fundamental challenges of intracellular therapeutics. Our proprietary EEV? platform is designed to engage targets previously considered inaccessible and undruggable and has the potential to translate into substantial improvements in efficacy, safety and tolerability of future medicines. Learn more about our EEV?-therapeutics: https://lnkd.in/dcFuBP5F #Biotech #Oligonucleotides #EndosomalEscape

Rubbish in rubbish out! This is just one legacy piece of advice Martin Coldwell my legendary boss taught me at AstraZeneca Fit for purpose another nugget of gold from another legendary boss Jean Qiu. Conigen Bioscience, Inc. can help you remove the rubbish and create tools that will be fit for your biological research. #biologics #oncology #biotechnology

Learn how CDER research is helping to inform how peptides and protein therapeutics that are not monoclonal antibodies should be regulated in the latest Regulatory Science Impact Story: https://lnkd.in/e4kX6SwQ

???????? ????????????????? ???? ??????????????! For over 30 years, Intavis Peptide Services has been a leading expert in the peptide industry. Renowned for producing ????????-?????????????? ???????????? ?????? ???????????????? ????????????????, as well as pioneering ??????????????-?????????? ????????????????, we conduct all our production and services in our state-of-the-art facilities in Tübingen, Germany. In case you are planning in-vitro peptide research or a clinical trial on peptide therapeutics talk to our expert advisors now! Find the link in the comment. #ClinicalPeptides?#PeptideProduction #Biotechnology #peptides

Opening officially soon

The world of oligonucleotide therapeutics can feel like you’re in uncharted territory. Cytiva can be your guide. Learn what you need to know in our brand-new oligo infographic – everything from future-proofing to synthesis, purification, and filtration. https://lnkd.in/dES3fw2F #oligos #nucleicacids #oligonucleotides #genomicmedicine