Cliniqa的动态

?? Medical Lab Educational Series: Day 15! ?? Welcome back to another exciting challenge in our Study with Me series! ?? Today, we're diving into bone health and the crucial role of biomarkers in managing osteoporosis. Let’s put your diagnostic skills to the test! ?? ?? Today's Question: What role do CTx (C-terminal telopeptide) and NTx (N-terminal telopeptide) play in the management of osteoporosis? ?? A. Increased urinary excretion is diagnostic of early-stage disease B. Increased levels indicate a low risk of developing osteoporosis C. Decreased urinary excretion indicates a positive response to treatment D. The rate of urinary excretion correlates with the stage of the disease ?? Correct Answer: C. Decreased urinary excretion indicates a positive response to treatment! ?? ?? In-Depth Interpretation: CTx and NTx are bone turnover markers used to measure bone resorption (the process by which bone is broken down). These markers are often used to monitor the effectiveness of osteoporosis treatment. Decreased levels of CTx and NTx in urine indicate that treatment, such as bisphosphonates, is effectively slowing bone resorption. ?? High levels suggest rapid bone loss, putting a patient at higher risk for fractures. Monitoring these markers helps evaluate how well a patient is responding to therapy. ?? Why not the other options? A: Increased urinary excretion of CTx and NTx is not diagnostic of early-stage disease, though it indicates increased bone turnover. B: Increased levels suggest a higher risk, not a low risk of developing osteoporosis. D: The rate of urinary excretion doesn't correlate directly with the stage of the disease but with the current rate of bone turnover. ?? Key Takeaway: Monitoring CTx and NTx levels is essential in managing osteoporosis. A decrease in their levels is a good sign that the treatment is working to slow down bone resorption and reduce fracture risk! ?? Ready for more? Stay tuned for tomorrow's post in our Medical Lab Series as we continue exploring the wonders of diagnostics! You’re mastering the world of lab science! ???? #Health #MedicalLabScience #BoneHealth #LabTech #ClinicalDiagnostics #MedTwitter #LabLife #Diagnostics #Science #Osteoporosis #Biomarkers #MedEd #Healthcare #MedLabProfessionals #Learning #MedicalScience #Research #Innovation #Healthcare #MedicalLabScience #ScienceDaily #Osteoporosis #BoneHealth #LabTech #ClinicalDiagnostics #ResearchCommunity #LabLife #MedLabProfessionals #Diagnostics #HealthAwareness #MedEd #MedTwitter #BoneMarkers #HealthTech #Innovation #LabResults #MedicalTechnology #HealthcareInnovation #EducationMatters

**Understanding T-Bilirubin in Body Fluids: A Key Diagnostic Marker** Total Bilirubin (T-Bilirubin) is an important biomarker used in the diagnosis and monitoring of various medical conditions. ?? **What is T-Bilirubin?** T-Bilirubin is a yellow pigment formed by the breakdown of old red blood cells. It is processed by the liver and excreted in bile. Measuring T-Bilirubin levels in body fluids can provide valuable insights into liver function and other health conditions. **Why is T-Bilirubin Important?** - **Liver Health:** Elevated T-Bilirubin levels can indicate liver diseases such as hepatitis, cirrhosis, or bile duct obstruction. - **Bile Leakage:** High T-Bilirubin levels in peritoneal or abdominal drain fluid can be a sign of bile leakage. - **Pleural Effusion:** T-Bilirubin testing helps distinguish between transudative and exudative pleural effusions, aiding in the diagnosis of underlying conditions. **Clinical Applications:** - **Liver Function Tests:** T-Bilirubin is a key component of liver function tests, helping to assess liver health and diagnose liver diseases. - **Fluid Analysis:** Analyzing T-Bilirubin in body fluids like pleural or peritoneal fluid can aid in identifying the source of pathological fluid accumulation. - **Screening for Bile Leakage:** T-Bilirubin testing is useful in evaluating peritoneal fluid or abdominal drain fluid for bile leakage, which can occur after surgeries or due to liver conditions. **Understanding T-Bilirubin levels in body fluids can significantly enhance diagnostic accuracy and patient care. Stay informed and prioritize health!** 1: [Mayo Clinic Laboratories](https://lnkd.in/dEJF58mw) 2: [Cleveland Clinic](https://lnkd.in/dg_DME9X) 3: [University of Rochester Medical Center](https://lnkd.in/dyKczm54) #MedicalLaboratoryTechnology #Microbiology #Phlebotomy #LaboratoryTesting #DiagnosticTesting #HealthcareProfessional #MedicalTesting #ClinicalLaboratory #BiomedicalScience #HealthcareIndustry #MedicalScience #LaboratoryMedicine #ClinicalMicrobiology Source: (1) BFBL - Overview: Bilirubin, Body Fluid - Mayo Clinic Laboratories. https://lnkd.in/dEJF58mw. (2) Bilirubin Test: Understanding High vs. Low Levels & Its Causes. https://lnkd.in/dg_DME9X. (3) Total Bilirubin (Blood) - Health Encyclopedia - University of Rochester .... https://lnkd.in/dyKczm54. (4) Bilirubin Blood Test - MedlinePlus. https://lnkd.in/dXt67Vcz. (5) Bilirubin, Body Fluid | Test Detail | Quest Diagnostics. https://lnkd.in/dZYVpPUp. (6) en.wikipedia.org. https://lnkd.in/dRUkx4RK.

#Novartis live at #EHA2024 Satellite Symposium: Managing high-risk Polycythemia Vera: Time to throw a lifeline ??? After listening to the testimony of Mark Hill, a patient advocate living with #PV, our panel of experts have focused on how to improve "real world" patient care. They have discussed the current treatment patterns and the unmet needs based on the latest clinical data, including how it impacts treatment goals. Don't miss our highlights! #Novartis #Hematology

We're back with the answer of the first case. Clinical history: A 73-year-old female patient presents to the emergency room with abdominal pain in the flank and right iliac fossa, which started approximately 4 days ago, accompanied by nausea. CT findings: A retroperitoneal collection is projected subhepatically, extending inferiorly along the right parieto-colic gutter, heterogeneous due to the presence of internal gas bubbles. Foci and small gas bubbles extend inferiorly along the ascending colon to the ceco-appendicular region. At this level, the appendix appears at the base with thickened walls, up to 5 mm, possibly indicating a perforated appendix with a subhepatic collection. Surgical findings:?Perforated gangrenous acute appendicitis with generalized purulent peritonitis and appendiceal phlegmon. Histopathological exam: Two fragments of adipose tissue, with a partailly filiform appearance(diameter 3 mm) and partially thickened walls up to 1,3 cm, with fibrin on the surface. The second fragment is adipose tissue with areas of fibrosis and a filiform appendix. Acute appendicitis. Stay tuned for the next cases.

Saumya M. Shah, MD (USC Roski Eye Institute), Daniel Su, MD, David Boyer, MD, of Retina-Vitreous Associates Medical Group review what is known, and promised, about #Photobiomodulation, following the completion of 2 major trials. In exudative #AgeRelatedMacularDegeneration (#WetAMD), significant strides — such as the development of anti-vascular endothelial growth factor (#AntiVEGF) therapies — have pushed the treatment possibilities forward and rewritten the likely course of the disease for many patients. However, for most patients, #AMD is nonexudative (dry), and treatments for those patients remain largely limited.1,2 Recent developments in the form of #ComplementInhibitorTreatments (such as pegcetacoplan and avacincaptad pegol) are showing promise in slowing progression rates of #GeographicAtrophy (GA) — an advanced, vision-threatening form of #DryAMD affecting nearly 1 in 5 patients. But for the dry AMD patients without GA, a tremendous gap in therapeutic avenues persists. Read here: https://brnw.ch/21wI43f #Ophthalmology #Ophthalmologist #EyeHealth #EyeCare #DryAMD #InflammatoryMarkers #VisualAcuity #BestCorrectedVisualAcuity #BCVA #LIGHTSITE #ClinicalTrial #EyeResearch #MedicalResearch

?? Understanding Biopsies: A Crucial Diagnostic Tool in Modern Medicine ?? In the realm of medical diagnostics, biopsies play a pivotal role in identifying and understanding various health conditions. As a microbiologist and medical lab technologist, I’ve seen firsthand the impact of accurate biopsy results on patient care and treatment outcomes. What is a Biopsy? A biopsy involves the removal of a small sample of tissue from the body for examination under a microscope. This procedure helps in diagnosing diseases, including cancer, infections, and inflammatory conditions. Types of Biopsies: 1. Needle Biopsy: A minimally invasive procedure where a needle is used to extract tissue or fluid. 2. Surgical Biopsy: Involves removing a larger tissue sample through an incision. 3. Endoscopic Biopsy: Utilizes an endoscope to collect tissue from internal organs. Why Biopsies Matter: - Accurate Diagnosis: Biopsies provide definitive information about the presence and extent of disease. - Guiding Treatment: They help in tailoring treatment plans specific to the patient's condition. - Monitoring Progress: Biopsies can be used to assess the effectiveness of ongoing treatments. The Process: 1. Preparation: The area is cleaned and numbed. 2. Sample Collection: Tissue is carefully extracted. 3. Analysis: The sample is examined by a pathologist to identify abnormalities. Advancements in Biopsy Techniques: With advancements in technology, biopsy procedures have become more precise and less invasive. Techniques like image-guided biopsies and molecular analysis are enhancing diagnostic accuracy and patient comfort. Conclusion: Biopsies are a cornerstone of diagnostic medicine, offering critical insights that guide patient care. As we continue to innovate and improve these techniques, the future of diagnostics looks promising. #MedicalLaboratoryTechnology #Microbiology #Phlebotomy #LaboratoryTesting #DiagnosticTesting #HealthcareProfessional #MedicalTesting #ClinicalLaboratory #BiomedicalScience #HealthcareIndustry #MedicalScience #LaboratoryMedicine #ClinicalMicrobiology #InfectionControl #PhlebotomyTechnician #MedicalLabTechnician #MicrobiologyLab #ClinicalLab #HealthcareCareer #MedicalCareer #ScienceCareer #COVID19Testing #Virology #Bacteriology #Parasitology #MolecularDiagnosis #GeneticTesting #Cytology #Histopathology #Immunology #Serology

?????? ?????????? ???? ?? ???????????? ??????????????: ?????? ???????? ???????? ?????? ???????? ???? ???????????? ?????????????????? Ever wondered why some patients????????? ???? ?????? ?????? ???????? ??????????????????, even when the OCT shows fluid? Turns out, it is not always about what we see—but what we believe in. Our recent study took a closer look at this by having three Reading Centers (ＧＲＡＤＥ, ＣＩＲＣＬＥ, Ｍ３) review OCT images. The results? In everyday practice, fluid is missed more often than we would like to admit. And even when it’s spotted,?????? ?? ?????????? ???? ?????????? treatment is skipped for diabetic macular oedema or oedema secondary to retinal vein occlusions. What is the reason? Sometimes, it is our own hesitation to act when we are not convinced ourselves. The classic excuse of “stable function” does not really cut it, especially when the potential for further improvement is right there! So, how do you tackle the tricky decision of "Treat of Not to Treat"? Many thanks to Georg Spital, Steffen Schmitz-Valckenberg, Bettina Müller, Erika Liczenczias, Petrus Chang, Britta Heimes?Bussmann, and Sandra Liakopoulos the whole ORCA team! ???????????? ????????: Interpretation of SD-OCT imaging data in real-life conditions versus standardized reading centre analysis in eyes with diabetic macular oedema or macular oedema secondary to retinal vein occlusion: 24-month follow-up of the ORCA study. Graefes Arch Clin Exp Ophthalmol. 2024 Sep 19. doi: 10.1007/s00417-024-06579-7. https://lnkd.in/ejt8_-Qi #4EyesPrinciple #Ophthalmology #RetinalDiseases #SecondOpinion #PatientCare #ClinicalDecisions

Great to have had the chance to read this independent report, created by Edge Health UK and commissioned by NHS England Outpatient Recovery & Transformation and the subsequent blog published by Julia Schofield (links below). Too much discourse online around AI in medicine is noise ?? at the extremities (hype ?? + despair ?? ). The Edge Health UK team have avoided falling into that trap. They’ve created a holistic report that not only covers the basics: - ? ?? the unmet need... 170% increase in USC referrals in England over the last 10 years, yet 24% of Dermatologist consultant positions are unfilled ?? - ?? ?? Fundamental requirements to be deployed within clinical pathways But goes further, wading into some of the complexity around: - ?? Benchmarking diagnostic accuracy standards in standard of care from the literature - ?? Proposing benchmarks for AIaMD against that performance And ultimately ends up making some actionable recommendations around post-market surveillance ?? Huge respect for the authors. ---------------------------- I’d really recommend reading the full report - https://lnkd.in/eTp4pHMq But if you’re after a shorter read: Julia Schofield blog - https://lnkd.in/ePtNBPf4? Skin Analytics slider - https://lnkd.in/eAAycRwT ?

?? In 2023, 14% of all tests sent to the EHR through Relaymed were blood panels, including haematology tests. Today is World Anemia Awareness Day which spotlights the condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body’s tissues, which is very prevalent in our society amongst women and children. To learn more:?https://lnkd.in/eDe8nyj2 ?? Relaymed helps automate diagnostic test results to your EHR in an error-free and streamlined process, ensuring crucial tests like red blood counts (RBC) are reported accurately and automatically. Explore our product:?https://lnkd.in/eMNsMKwR #worldanemiaawarenessday #anemia #diagnostics #hematology #bloodtest #ehr #medtech #diagnostictesting #digitalhealthcare #pointofcaretesting #pointofcare

?? Listen to the latest news bulletin from National #Health Executive ?? ?? Regulations and #NHS tendering requirements delaying innovation, says HealthTech industry ?? WHO: vaccine investment key to combating antimicrobial resistance ?? New heart surgery technique broadcast to international audience For more details on all our stories, check out https://lnkd.in/eQ8QtbEH ABHI CPI #HealthTech #Technology #Regulation World Health Organization #AMR #AntimicrobialResistance #Antibiotics #GlobalHealth #Vaccines #Pharma Sheffield Teaching Hospitals NHS Foundation Trust #Cardiology #HeartSurgery #Research #ClinicalTrials