Principal Research Assistant at Noguchi Memorial Institute for Medical Research | Bioinformatics - Bacteria Genomics | Trained Field Epidemiologist
????As a scientist, few things are more fulfilling than seeing the fruits of countless days and nights of hard work shared with the world. With immense dedication, we are thrilled to announce the publication of one of the most comprehensive studies on Staphylococcus aureus using whole-genome sequencing in Ghana??! Over the past three years, we collected S. aureus isolates implicated in infections from 10 hospitals across Ghana. Using advanced genomic sequencing and bioinformatics tools, we delved into their genetic makeup to uncover critical insights. ??Our findings shed light on how this organism is evolving over time, the strategies it employs to survive in our environment, evade antibiotics, and enhance its pathogenicity. ??A particularly striking discovery was the high prevalence of methicillin-resistant S. aureus (MRSA), especially the ST152 clone. This strain, once predominantly methicillin-sensitive, has evolved into being predominantly MRSA . ST152 is a pandemic clone known to cause hospital outbreaks globally—a concerning development with significant implications for infection control. ??This study underscores the critical need for genomic surveillance in combating antimicrobial resistance (AMR). Integrating such innovative approaches into public health strategies cannot be overstated. ????A heartfelt thank you to SeqAfrica DTU Team for their unwavering support, to Beverly Egyir, PhD for her outstanding leadership, mentorship, and guidance as principal investigator, and to the incredible NMIMR AMR Hub Seqfrica team for their hard work and collaboration ??. For more details, check out the paper—it’s a compelling read!?? https://lnkd.in/e6QN7T6c
Antimicrobial Resistance Investigator, Co- Founder-Seers Foundation, Senior Research Fellow at the Bacteriology Department, Noguchi Memorial Institute for Medical Research, University of Ghana.
??Our new publication ???? ?? Provides insights into whole genome characteristics of 159 Staphylococcus aureus from clinical sources collected across ten hospitals in Ghana. ??Highlights the predominance of ST152 methicillin-resistant clones, signaling a significant transition from ST152 MSSA to ST152 MRSA over the last decade. ??Our findings underscore the critical need for genomic surveillance using whole genome sequencing to effectively track and mitigate the spread of multidrug-resistant organisms like MRSA in Ghana. Heartfelt thanks to all co-authors for the diverse and invaluable contributions. #SeqAfrica #TheFlemingFund #NMIMRAMRHub #DTU
Graduate Research Assistant | Doctor of Philosophy - PhD
2 个月Congrats Christian Owusu-Nyantakyi