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????????’?? ???????? ?????? ?????????????? ????????????????????????? As GLP-1 agonists pave the way to becoming the top-selling drugs of 2024, the biopharma industry is innovating further to enhance the quality of weight loss treatments. "While current GLP-1 drugs are making remarkable strides," says Paul Titchenell of UPenn, "there's always room to enhance efficacy." Studies indicate that existing therapies might inadvertently lead to muscle loss, especially concerning for elderly patients. Altimmune's Scott Harris notes, "Loss of muscle mass poses risks, particularly for older adults." To address these concerns, biopharma leaders are investing in novel approaches. Eli Lilly's acquisition of Versanis and its promising asset bimagrumab exemplifies this shift. Bimagrumab aims to reduce fat mass without compromising muscle mass, offering a new dimension to weight loss therapy. Similarly, Biohaven's taldefgrobep and Altimmune's pemvidutide are ushering in a new era of targeted treatments. These compounds not only aid in weight reduction but also preserve lean muscle mass, crucial for long-term health. According to Mayank Mamtani of B. Riley Securities, these advancements herald a future where weight loss treatments are more nuanced and effective. "The goal is to achieve sustainable weight loss," Mamtani emphasizes. Vipin Garg of Altimmune envisions a market where various mechanisms cater to diverse patient needs. "There's room for multiple blockbuster drugs," Garg asserts, highlighting the evolving landscape of obesity medicine. As the quest for optimal weight loss continues, one thing remains clear: innovation in biopharma is reshaping the future of healthcare, one breakthrough at a time. Contact??BIOBOSTON CONSULTING?today or visit our??website?to learn more about how we can support your organization. #pharmaceuticals #biotechnology #medicaldevices #consulting #fda #ObesityMedicine #BiopharmaInnovation?

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