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Catching breast cancer early when it is localized is crucial, as the five-year relative survival rate is 99%. But how can genetics be used to identify more women at risk of breast cancer? ? Check out Allelica, Inc’s new article describing how PRSs are used to mitigate breast cancer disease risk, including: - How primary care physicians can integrate this information into standard clinical breast cancer risk assessments - How integrating PRSs into established risk models like the Tyrer-Cuzick and BOADICEA leads to more accurate risk assessments - How risk conferred by high PRSs is equivalent to risk of disease from rare pathogenic variants If you are interested in using clinical practice, get in touch! https://lnkd.in/g2fQVhvW

Polygenic risk scores for breast cancer prevention: a guide for physicians

Polygenic risk scores for breast cancer prevention: a guide for physicians

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