美国 加利福尼亚 圣地亚哥 联系方式
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Published scientist, patent co-inventor and educational multimedia producer.

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志愿者经历

  • MASS AWIS图片

    Mentor

    MASS AWIS

    - 1 年 11 个月

    Science and Technology

    Mentor for a small group of women scientists committed to meeting regularly facilitating support, career advice and information.

  • Compassion for Migrant Children图片

    After School Teacher

    Compassion for Migrant Children

    - 1 年

    Children

    • Organized after-school program for children in Beijing whose parents are migrant workers from rural China
    • Interviewed volunteers and children, filmed a documentary


  • S.H.I.N.E.图片

    Mentor

    S.H.I.N.E.

    - 6 个月

    Science and Technology

出版作品

  • Sequence-independent recognition of the amyloid structural motif by GFP protein family

    Proceedings of the National Academy of Sciences (PNAS)

    GFP and other related fluorescent proteins (FPs) are widely used in biological sciences. We discovered that FPs have an intrinsic high binding propensity for the core of amyloid fibrils. We have demonstrated this using over 10 different amyloid fibrils, characterized the binding interface, probed binding interface via mutagenesis, and performed a number of controls to show that binding is specific to amyloid structures and not to other nonamyloid fibrillar structures or soluble proteins with…

    GFP and other related fluorescent proteins (FPs) are widely used in biological sciences. We discovered that FPs have an intrinsic high binding propensity for the core of amyloid fibrils. We have demonstrated this using over 10 different amyloid fibrils, characterized the binding interface, probed binding interface via mutagenesis, and performed a number of controls to show that binding is specific to amyloid structures and not to other nonamyloid fibrillar structures or soluble proteins with extended β-structure. This previously unrecognized functionality of FPs has two major implications: 1) It provides a tool to study amyloid structures, and 2) It suggests that caution should be taken when FPs are used as a fusion to visualize the cellular localization of proteins of interest.

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  • Gallic Acid Is an Antagonist of Semen Amyloid Fibrils That Enhance HIV-1 Infection

    The Journal of Biological Chemistry

    http://www.asbmb.org/asbmbtoday/201610/JournalNews/JBCSperm/
    Highlighted in American Society for Biochemistry and Molecular Biology Today October 2016 Issue

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  • Is CO adequate to facilitate the formation of Pt3M (M = Fe, Ni and Co) nanocubes?

    Chemical Communications

    We explore the possibility of preparation of Pt3M (M = Fe, Ni and Co) nanocubes using carbon monoxide as an alternative protocol under different experimental conditions. The results suggest that the sole carbon monoxide flow at ambient pressure can enable the formation of binary Pt–M nanocrystals, but it is inadequate to facilitate the formation of Pt3M nanocubes in the given system under specified conditions.

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专利发明

  • Systems and Methods for Binding Amyloid Fibrils Using Fluorescent Protein.

    申请日期: US 104061-201

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荣誉奖项

  • High Scholarly Achievement in the Departmental Honors Program Distinguished Independent Work in Chemistry

    Binghamton University Harpur College of Arts and Sciences

  • Tau Sigma national academic honor society

    Tau Sigma National Honor Society

    "Recognizing and Promoting the Academic Excellence and Involvement of Transfer Students"

  • Dean's list

    Binghamton University

  • Undergraduate Outstanding Research

    Harpur College Awards Committee

    Twice in 2011 and 2012

语言能力

  • English

    母语或精通双语

  • Chinese

    母语或精通双语

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