Researchers from the University of Strathclyde explores the role of antibody-antigen binding kinetics in shaping the biological function and therapeutic success of antibodies. Understanding these interactions is essential for predicting pharmacological behavior and ensuring smooth clinical translation. ? Advances in antibody engineering and novel formats to fine-tune binding. ? Cutting-edge technologies for measuring antibody-antigen interactions. ? The rise of computational modeling to predict binding under physiological conditions. ? Insights into how modulating target engagement impacts pharmacodynamics (PD) and pharmacokinetics (PK). Read the full study here: https://lnkd.in/eVAeub5b #Biointron #Antibodies #Immunotherapy #Oncology #Healthcare Study by James Lodge et al.
Senior Scientist at GSK and Collaborative PhD Student at the University of Strathclyde
4 天前Thanks for sharing our work!