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Clinical relevance of patient response diversity to precision medicine This diversity is not just inequitable; it also leads to missed opportunities. Complex phenotypes and many physiological conditions alike are shaped by the interaction between multiple genes. When precision drugs aren’t diverse enough, clinicians miss out on unresponsive patients. When a drug is developed to target a gene, it might be effective against only one genetic variant that might not be prevalent in other ethnicities. Conversely, studying drug repurposing with precision functional genomics could provide insights into the disease and what’s driving it. Instead of targeting gene variants identified by analyses of tumor genome sequencing and spending billions, years to develop new drugs, “we have an opportunity to find new pathways and new technologies that we can predict efficacies of existing cancer drugs for each individual patient,” said OncoDxRx. ? “This is also relevant to understanding how potential therapeutics could interact with variants of the same genes in different populations. If a disease has a low prevalence in a community, it could be because there are genetic modifiers that have a protective effect.” https://lnkd.in/gvKNT9Gn #opportunities #strategy #programming #design #team #research #data #health #development #collaboration #projects #testing #immunotherapy #cancer #technology #biotechnology #healthcare #medicine #oncology #precisionmedicine #liquidbiopsy #rna #dna #venturecapital #startup #immunooncology #tcells #innovation #growth #tech #lifesciences #biopharma #oncodxrx #genomics #NGS #CRISPR #gene #geneexpression #artificialintelligence #machinelearning #sequencing #cancerresearch #personalizedmedicine #targetedtherapy #PrecisionOncology #Therapy?

?? ?????? ????????-???????????????????? ????????????????????: ?????????????????????????????? ?????????????? ???????????????? ?????? ?????????????????? ???????????????? The RNA Next-Generation Sequencing (NGS) market is centered on advanced sequencing technologies for analyzing RNA to understand gene expression, mutations, and transcriptome profiling. It is widely used in research, diagnostics, and drug discovery, driving personalized medicine and advancements in oncology, immunology, and infectious diseases. Key Market Trends Increased Adoption in Oncology: RNA sequencing is crucial for understanding cancer biology and tailoring treatments. Growth of Transcriptomics: High demand for comprehensive RNA profiling in genomics research. Technological Advancements: Innovations in NGS platforms and data analytics boost adoption. ?????????? ???????? ???? ???????????????? ?????? ???????? ???????????? ????????????:?https://lnkd.in/g7v25eGf #Company | Roche | Illumina | Thermo Fisher Scientific | Beckman Coulter Diagnostics | Pacific Biosciences | Oxford Nanopore Technologies | Eurofins Scientific Finland Oy | Macrogen Europe | GENEWIZ | Berry Genomics | QIAGEN #Type Enrichment Approaches Amplicon-Based Approaches #Applications Research Institutes Hospitals and Clinics Biotechnology Company Diagnostic Lab ?????????? ????????, ???? ?????? ?????????????? ???????????? https://lnkd.in/dKh4YWp7 #Genomics #RNASequencing #PrecisionMedicine #NGS #Biotechnology #HealthcareInnovation #PersonalizedMedicine

??????????????????????: ?????????????????? ?????? ?????????????????? ???? ???????????????????? ???????????????????? The global?epigenetics market size?was estimated at USD 14.63 billion in 2023?and is projected to grow at a CAGR of 15.3% from 2024 to 2030. This growth can be attributed to the pivotal role of epigenetics in understanding gene regulation beyond #DNA sequencing, aiding disease research, and advancing personalized medicine. ???????????????? ???????????? @ https://lnkd.in/gbedWF88 ???????? ?????? ???????? ?????? ???????????????? ???????? ?????? ????????????: Cancer treatment is a major driver, with epigenetic therapies like DNA methyltransferase (DNMT) inhibitors and histone deacetylase (HDAC) inhibitors gaining traction. These therapies target specific epigenetic mechanisms to stop cancer growth, and new combination therapies are being developed to increase efficacy. Advances in CRISPR/Cas9 technology are enabling precise epigenetic modifications without altering the DNA sequence. This opens new possibilities for treating diseases linked to gene regulation, such as cancer, genetic disorders, and neurodegenerative diseases. Personalized medicine is benefiting from epigenomic mapping technologies like single-cell sequencing. By understanding individual epigenetic profiles, more precise, tailored therapies are being developed for complex diseases. ?????? ???????? ?????????????????????? @ https://lnkd.in/gmbaKsMZ ?????? ?????? ??????????????: Thermo Fisher Scientific | Eisai US | Novartis | Illumina | Promega Corporation | Merck Group | Hologic Diagenode | New England Biolabs #Epigenetics #Biotechnology #GeneExpression #PrecisionMedicine #CancerResearch #Genomics #CRISPR #PersonalizedMedicine #EpigeneticTherapies #LiquidBiopsy #DNASequencing #LifeSciences #GeneTherapy #Pharma #HealthcareInnovation

?????????????????????? ???????????? ?????????? $4.3 ?????????????? ???? 2028 Download PDF Brochure @ https://lnkd.in/drWDmdW5 The size of global ?????????????????????? ???????????? ???? ?????????? ???? ?????????????? ?????? ?????????????????? ???? ???? ?????????? $1.8 ?????????????? ???? 2023 ?????? ???? ???????????? ???? ?????????? $4.3 ?????????????? ???? 2028, ?????????????? ???? ?? ???????? ???? 18.3% from 2023 to 2028 #Epigeneticresearch has the potential to advance the understanding of gene expression and its role in various #diseases including #cancer, #neurologicaldisorders, #autoimmunediseases, and more. #Pharmaceutical and #biotechnology companies are allocating substantial resources to unravel the complexities of epigenetic mechanisms, aiming to harness their therapeutic potential. For instance In September 2023, Harbinger Health r?????????? ?????? 140 ?????????????? ?????????????? ???? ???????????? B funding with founding investor Flagship Pioneering, alongside new global institutional investors including Pictet, Partners Investment, and Catalyst, among others. The company plans to use the new funds to support the completion of its ???????????? ???????????? ??????????????????????-?????????????????? ???????????? (????????-????) ???????????????? ??????????. The firm's platform, HarbingerHx, uses machine learning to identify epigenetic patterns associated with tumor development. The company expects to launch its first product — a laboratory developed test for detection of early cancer — in 2025 ?????????????????????? ?????????????????? ???????????? ???????? ????????????????: Kokoro ????? Centre for Molecular Medicine and Therapeutics????? More Than Health AG????? Global Health Clinics???? Institute of Gene Biology Russian Academy of Sciences???? Presence Wellness????? CosmoMK Numbers Phenomena?? 数字现象?? ??? Developmental Neuroanalytics Lab at the University of Virginia????? Kensh???? A Healthy You!?????

Advancing Precision Medicine with ASO & siRNA Technologies ?? Antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs) are at the forefront of gene silencing technologies, offering innovative solutions for targeting diseases linked to aberrant gene expression. Here's why these tools are game-changers: ?? High Specificity: Precisely target mRNA to block disease-related protein production. ?? Broad Therapeutic Potential: Effective for conditions like cancer, rare genetic disorders, and viral infections. ?? Non-Permanent & Reversible: Unlike gene editing, their effects can be fine-tuned with dosing adjustments. ?? Cost-Effective & Scalable: Synthesized rapidly, enabling faster development and large-scale applications. ?? Breakthrough in Delivery: Recent advancements allow crossing the blood-brain barrier, expanding use in CNS diseases. ?? Market Insights: The global ASO and siRNA therapeutics market is projected to grow from $4.38B in 2023 to $14.35B by 2030 (CAGR of 18.72%), driven by advancements in molecular biology and the demand for personalized medicine. As molecular therapies evolve, ASOs and siRNAs provide hope for undruggable targets and diseases with limited treatment options. Let’s connect to discuss how these innovations can transform your research! ?? hashtag #GenomicMedicine hashtag #ASOTechnology hashtag #PrecisionTherapeutics If you like our content creation, get in touch with us to see how we might be able to assist you.

?????????????????????? ?????????????? ???????????? ????????????????, ?????? ????????????, ???????????? ??????????????????????????, ???????????????????? ?????? ?????? ?????????????? ???? ???????? The Karyotype Analysis Service Market provides diagnostic services focused on analyzing an individual's chromosomal composition. This analysis is critical for identifying genetic abnormalities, diagnosing conditions such as Down syndrome, Turner syndrome, and certain types of cancers, as well as for prenatal screening and fertility treatment. Karyotype analysis is a widely used genetic tool in both clinical diagnostics and research. ?????????? ????????, ???? ?????? ???????? ???????????? ???????????? https://lnkd.in/eqG3b78v Market #Drivers: Increasing Prevalence of Genetic Disorders: A rise in genetic disorders and congenital abnormalities has driven the demand for karyotype analysis, especially in prenatal screening. Advances in Genomics and Cytogenetics: Technological advancements, including digital karyotyping and automation in laboratories, have improved accuracy and efficiency, fueling the growth of this market. Growing Use in Oncology: Karyotype analysis is increasingly used in cancer diagnostics to detect chromosomal abnormalities linked to various cancers. ?? ???????????? ??????????????????????????: Global Karyotype Analysis Service Market: By #Company ? Thermo Fisher Scientific ? Creative Bioarray ? Applied StemCell ? Cell Guidance Systems ? KARYOLOGIC, INC. ? Igenomix, Part of Vitrolife Group ? Creative Biolabs ? BioReliance ? Labcorp ? Beijing Abaco Biotechnology ? Cyagen Global Karyotype Analysis Service Market: By #Type ? G-banding Analysis ? Whole Genome Sequencing Analysis ? Others Global Karyotype Analysis Service Market: By #Application ? Academic and Research Institutes ? Government ? Biopharmaceutical ? Others ?????????? ???????? ???? ?????? ???????????????? ???????????? https://lnkd.in/eCvKMgjJ ? ????????????-Stringent Datalytics - Information Technology #KaryotypeAnalysis #GeneticTesting #Cytogenetics #CancerDiagnostics #PrenatalScreening #ChromosomalAbnormalities #MedicalGenetics #HealthcareTechnology #FertilityDiagnostics #GeneticDisorders

Exciting News in Transplant Medicine! Verici Dx is excited to share the latest advancements in post-kidney transplant care, where RNA sequencing technology coupled with machine learning is revolutionizing our approach to differentiating and managing complications like BK virus nephropathy (BKN) and acute rejection. RNA sequencing enables a comprehensive analysis of gene expression patterns, offering valuable insights into the molecular mechanisms underlying these conditions. By analyzing gene expression profiles, researchers are identifying unique biomarkers specific to rejection enabling clinicians to differentiate between BKN and acute rejection, paving the way for more precise diagnosis and personalized treatment strategies. One such promising biomarker is Tutivia, a leading-edge diagnostic tool that utilizes RNA sequencing technology to analyze gene expression patterns associated with acute rejection. Tutivia offers a non-invasive and highly specific method for risk probability of acute rejection with no false positives occurring in patients with BK nephropathy, helping clinicians tailor treatment plans to each patient's specific needs. With Tutivia and RNA sequencing technology, we're not just identifying injury that has occurred – we're getting to the root of the problem, offering actionable data, and advancing the field of transplant medicine. It's an exciting time for innovation and progress in healthcare, and Verici Dx is thrilled to be a part of it! https://lnkd.in/gjQ-NNQw #TransplantMedicine #RNASequencing #ClarityEvenEarly #PrecisionMedicine #TutiviaDelivers #HealthcareInnovation

?? A Complete Guide on Genomic Biomarkers ?? ?? What is a Genomic Biomarker? A genomic biomarker is a specific gene, genetic variation, or expression pattern in DNA that can be used to identify biological processes, disease states, or responses to therapies. These biomarkers are valuable in diagnosing diseases, predicting treatment outcomes, and personalizing medical interventions. Genomic biomarkers play a crucial role in advancing precision medicine by enabling more targeted and effective healthcare solutions1. ?? Development and Applications: Genomic biomarker development focuses on identifying specific genetic mutations, expression patterns, or variations linked to diseases or therapeutic responses. Advances in genomic sequencing technologies and bioinformatics have accelerated the discovery of these biomarkers, enhancing their application in personalized medicine. This development aids in early disease detection, predicting treatment efficacy, and guiding more precise and individualized healthcare strategies2. ?? Why It Matters: Understanding and utilizing genomic biomarkers is essential for the future of healthcare. They provide critical insights that help tailor treatments to individual patients, improving outcomes and reducing side effects. This personalized approach is transforming how we diagnose and treat diseases, making healthcare more efficient and effective. ?? Leading Players: - Thermo Fisher Scientific - F. Hoffmann-La Roche AG - Liquid Genomics, Inc. - AROS Applied Biotechnology A/S - Myriad Genetics, Inc. - QIAGEN - Eurofins Scientific - Genomic Health - Bio-Rad Laboratories, Inc. - Epigenomics AG - Aepodia #GenomicBiomarker #PrecisionMedicine #PersonalizedMedicine #Biotechnology #HealthcareInnovation #MedicalLaboratoryTechnology #Microbiology #Phlebotomy #LaboratoryTesting #DiagnosticTesting #HealthcareProfessional #MedicalTesting #ClinicalLaboratory #BiomedicalScience #HealthcareIndustry #MedicalScience #LaboratoryMedicine #ClinicalMicrobiology #InfectionControl #PhlebotomyTechnician #MedicalLabTechnician #MicrobiologyLab #ClinicalLab #HealthcareCareer #MedicalCareer #ScienceCareer #COVID19Testing #Virology #Bacteriology #Parasitology #MolecularDiagnosis #GeneticTesting #Cytology #Histopathology #Immunology #Serology

Genetic Editing Therapies : Upcoming Trends Analysis 2023-2033 To Request Sample Report: https://lnkd.in/dbhWp89c Genetic Editing Therapies Market is on a remarkable growth trajectory, expected to expand from $10.5 billion in 2024 to $50.2 billion by 2034, with a robust CAGR of approximately 17.2%. Global Insight Services This surge is fueled by rapid advancements in gene-editing technologies such as CRISPR-Cas9, TALENs, and ZFNs, which are revolutionizing medical treatments by precisely modifying DNA sequences. These breakthroughs are unlocking new possibilities for treating genetic disorders, developing innovative cancer therapies, and advancing agricultural biotechnology. The rising demand for personalized medicine, coupled with increasing investment in biotechnology research, is driving market expansion, positioning genetic editing as a game-changer in modern healthcare. The oncology segment leads the market, driven by the urgent need for groundbreaking cancer treatments that target genetic mutations at their source. Neurological disorders represent the second-highest performing sub-segment, as research intensifies to develop therapies for conditions like Alzheimer’s, Parkinson’s, and Huntington’s disease. Regionally, North America dominates due to its strong research infrastructure, government funding, and favorable regulatory landscape. Europe follows closely, benefiting from significant investments in biotech innovation and supportive healthcare policies. Meanwhile, the Asia-Pacific region, particularly China and Japan, is witnessing rapid growth due to expanding healthcare initiatives, increasing biotech investments, and a rising demand for advanced medical solutions. As the genetic editing therapies market evolves, ethical considerations and regulatory frameworks remain key challenges. Companies and research institutions must strategically navigate these complexities to ensure responsible and effective deployment of gene-editing technologies. With continuous advancements, strategic collaborations, and growing market opportunities, genetic editing is poised to reshape the future of medicine and biotechnology. #geneediting #crispr #biotech #genetictherapy #precisionmedicine #genomeengineering #cancerresearch #dnaediting #biotechnology #genomics #futureofmedicine #medicalbreakthroughs #biotechinnovation #geneticdisorders #oncologyresearch #personalizedmedicine #healthcareinnovation #genetherapy #biopharma #lifesciences