晶泰科技

Small, specific, and high-affinity: peptides have it all. Yet, despite their growing market potential, challenges like poor stability and cell permeability persist, often requiring time-consuming cycles of screening and refinement. At XtalPi, we use AI-driven design to generate stable, effective peptides from the start, streamlining discovery. Click here https://hubs.li/Q038zQ340 to learn more about the AI design in PepiX?: ? High Quality Data: Combines public data, proprietary insights, and in-house experimental data for accurate and versatile peptide design. ? Integrated AI Models: Backbone Generation, Sequence Filling, and Structure Screening work seamlessly for efficient design and screening. ? Proven Success: Designed peptides de novo for protein targets across 20+ projects. #peptidediscovery #peptidedesign #artificialintelligence

Join us at Association for the Advancement of Artificial Intelligence (AAAI) to hear about XtalPi's breakthrough advances in mRNA design. Dr. Xiangrui Gao will be presenting the poster "mRNA2vec: A Language Model Embedding Method Based on 5'UTR-CDS to Assist mRNA Design" (ID: 12844) on February 27, 12:30pm-2:30pm. Stop by to learn how mRNA2vec leverages proprietary language models and machine learning to significantly enhance mRNA expression levels and stability, paving the way for future therapies. Check out our digital poster here: https://hubs.li/Q038m-9z0 #mRNA #AAAI2025 #artificialintelligence #drugdesign

Operations are in full swing at our Boston lab! Since opening two months ago, our new facility has become a hub of innovation that integrates AI, automation, and wet and dry lab to streamline the polymorph discovery process. Read our case study to learn the key benefits of our workflow: https://hubs.li/Q038grM60 ? Faster Development Timelines, as AI and expert insights combine to deliver higher solid yields and improved success rates ?? Key Structural Insights with techniques like XRPD refinement, MicroED, and single-crystal XRD to quickly and accurately elucidate structures ?? Increased Polymorph Stability through advanced methods that identify the optimal low-energy solid forms Contact us: [email protected] #polymorphscreening #solidstateresearch #artificialintelligence #automation

?? Did you know our founders met over pizza at MIT? Massachusetts Institute of Technology (MIT)—one of the world’s leading hubs for scientific innovation—has been shaping the future of technology and science since 1861. In 2015, XtalPi's founders crossed paths in Boston, bonding over their shared dreams for drug discovery. Today, we continue to build on our Boston roots with our US office and Somerville lab, focused on advancing drug discovery with AI and automation. #XtalPi360 #XtalPiStory #drugdiscovery #MIT #Boston

Robot Showdown! ?? Robots have always fascinated us—whether they're exploring space, assisting with everyday tasks, or driving scientific innovation. Today, we're putting some of the most iconic robots to the test, and we need to know: which one is your favorite? (Ours is the workstation, but we don't want to influence you ??) Cast your vote below and let us know why!

Dive into our fully integrated compound creation—where automation and digitalization come together to make your research and development faster, smarter, and more efficient. ?? 24/7 Streamlined Workflow: smooth and continuous processing from starting material to final results ?? Versatile Workstations: designed to handle everything from library synthesis to solid-state research and material science. ?? End-to-End Digitalization: enabling seamless data management Follow us for more insights into our automated workflows! #automationlab #librarysynthesis #digitalization #robotics #artificial intelligence

Screen More for Less—XFEP Delivers Faster, Cost-Effective FEP Calculations FEP offers precise binding affinity predictions but is often constrained by high computational costs, limiting calculations to only hundreds per week. XFEP changes the game—processing thousands of binding affinities per week. With a proprietary force field, optimized algorithms, and unlimited GPU power, XFEP accelerates free energy calculations while minimizing resource demands and delivering unmatched accuracy and efficiency. Plus, flexible licensing ensures seamless integration into any workflow. ?? Maximize throughput. Cut costs. Accelerate drug discovery. Contact us https://lnkd.in/e_3deXvj to learn more about XFEP. #XFEP #FEP #artificialintelligence #drugdiscovery

Is it just us, or is there real chemistry in the air today? ?? Let’s take a moment to reflect on XtalPi’s first love—computational chemistry. Chemistry was an experimental discipline until quantum mechanics emerged in the early 1900s and brought a new understanding of the theory behind atoms. Unfortunately, this groundbreaking discovery was limited by the computational tools of the time, who couldn't handle complex equations. Today, advances in computing and AI are transforming computational chemistry, with powerful algorithms to tackle these complex systems. At XtalPi, our mission is to leverage this technology to redefine drug discovery. How do you see AI shaping the future of drug discovery? Let us know in the comments. #XtalPi360 #ComputationalChemistry #chemistry #artificialintelligence

Introducing PepiX: our AI-powered peptide discovery platform. Peptides are gaining momentum in the pharma industry, and for good reason: they combine the specificity of antibodies with the oral availability of small molecules. But challenges remain: poor intracellular delivery, instability, and rapid clearance. Here's how PepiX is streamlining peptide discovery: ?? AI-driven peptide design: peptides are tailored to binding sites, even without known protein-protein interactions. ?? Optimized formats: 1,000+ non-canonical amino acids enhance stability and permeability. ?? AI-powered screening: AI predictions are combined with high-throughput screening, and the models learn from each iteration, getting better and better. We'll be sharing more about PepiX's unique capabilities soon, so follow us to stay in the loop! #PepiX #peptidediscovery #drugdiscovery #artificialintelligence

Crystal form screening is essential in drug development, but it’s often slow and costly. What if there was a faster, more reliable way to predict stable polymorphs? ?? We're excited to present our XtalGazer? CSP platform – an AI-powered solution that accelerates crystal structure prediction with an intuitive interface for users of all technical backgrounds. With real-time processing and AI-driven calculations, you can streamline workflows, save time, and reduce costs. Chat with us to learn more: https://lnkd.in/gNkeV8Vm ?? Watch our video below to see how we’re transforming polymorph screening. #polymorphscreening #solidstateresearch #artificialintelligence #crystalstructureprediction