Vizgen

?? Expanding the Limits of Discovery with MERSCOPE Ultra? ?? MERSCOPE Ultra provides an expansive 3 cm2 imaging area, allowing you to combine multiple experiments on a single slide. Easily image normal and diseased tissues, multistage embryos, or serial tissue sections—in one run. This setup eliminates batch effects and experimental variation, ensuring consistent and reliable results. Dive into complex biology with unmatched detail and seamless, high-quality data. ?? Learn more: https://hubs.ly/Q02Z879J0 #SpatialTranscriptomics #MERSCOPEUltra #Genomics #SpatialBiology

??Vizgen and Integrated Sciences team will be at the Multi-Omics 2024 Meeting from December 1-3, 2024, in Brisbane! ?? Visit Us at Booth #4 to discover how the MERSCOPE Ultra? Platform, powered by MERFISH, is redefining #SpatialGenomics with unparalleled resolution and scalability. ?? Don’t Miss Vizgen's Presentation: ?? Tuesday, December 3, 2024 ? 9:10 AM - 9:30 AM ?? Boulevard Auditorium Topic: Mapping the Future of Spatial Genomics with the MERSCOPE Ultra? Platform ?? Speaker: George Emanuel, Ph.D., Vizgen Scientific Cofounder & Senior Director of Technology & Partnerships ?Join us to win some fun prizes and explore how cutting-edge #SpatialTranscriptomics from Vizgen can accelerate your multi-omics research. #SpatialBiology #MultiOmics #MERSCOPEUltra #MERFISH

?? Unveiling Brain Complexity with Vizgen's 1000-plex Gene Panels?? We are excited to showcase the capabilities of Vizgen's MERSCOPE? Platform, in a study that deciphers the molecular and cellular features of human brain tissue ??under physiological and pathological conditions. ?? Highlights: - Leveraged a 960-plex gene panel to achieve unprecedented resolution in neuronal and non-neuronal cell types across various mouse brain regions. - Conducted a spatial multi-omics imaging assay to understand the pathogenesis of Alzheimer's Disease (AD), concurrently measuring gene expression and protein staining in human brain samples. - Identified cell-type-specific molecular and cellular adaptations, highlighting a spatially dependent response associated with AD. ?? Download the Dataset: Explore the MERFISH data files directly on your computer using your data analysis program of choice: https://hubs.ly/Q02Z3qXq0 #SpatialGenomics #MERSCOPE #MERFISH #Neuroscience #AlzheimersDisease #DataRelease

? The 2024 HCA Asia Meeting Starts Next Week! ?? We’re excited to announce our participation in the Human Cell Atlas (HCA) Asia Meeting, taking place on December 3-4, 2024, in Hong Kong! ?? Visit Us at Booth K to learn about the cutting-edge MERSCOPE Ultra? Platform, powered by MERFISH 2.0, and how it’s revolutionizing spatial transcriptomics research. ?? Scientific Poster Presentation: ?? Date: December 4, 2024 ? Time: 13:15-14:15 HKST ?? Poster #D2-31 Topic: Advances in Spatial Transcriptomics: Using 1000-plex Panels to Unlock Insights from Brain Tissue Samples with MERSCOPE Ultra? and MERFISH 2.0. #SpatialBiology #HCAAsia #MERSCOPEUltra #MERFISH

?? New Preprint Alert! Understanding how thousands of genes coordinate organ function across spatially distinct cell types is one of biology’s greatest challenges. In an exciting new study, Xiaowei Zhuang and colleagues introduce an innovative paired imaging (MERFISH) and sequencing (Perturb-seq) approach to tackle this problem. Using this multi-modal method, the team constructs genotype-phenotype maps by: ?? Identifying genetic perturbations in individual cells through imaging ?? Measuring transcriptomic responses via single-cell sequencing ??They apply this to the mouse liver, uncovering: ? Regulators of hepatocyte zonation ? Insights into liver unfolded protein response ? Distinct pathways driving hepatocyte steatosis This approach bridges the gap between genetic perturbations and cellular/tissue phenotypes, opening doors to new discoveries in organ function and providing critical data for machine-learning models of cell biology. ??Read the full preprint on bioRxiv: https://hubs.ly/Q02Z86xN0 #Genomics #MERFISH

?? Discover the power of MERFISH 2.0 Chemistry! ?? With better performance for challenging sample types, MERFISH 2.0 delivers enhanced sensitivity and performance by improving RNA anchoring and optimizing probe binding for superior transcript integrity and accessibility. The increased fluorescent signal builds on Vizgen's trusted MERFISH technology to bring your #SpatialGenomics insights to the next level. ???Sign up now to preview exclusive data from Vizgen and customer samples using MERFISH 2.0! ?? https://hubs.ly/Q02Z0Yf-0 #SpatialGenomics #MERFISH #Vizgen #MERSCOPE #MERFISH2

?? The 2nd Spatial Biology Congress Asia (Global Engage) Starts Today! ?? We’re thrilled to announce that Vizgen will be exhibiting at this year’s event and presenting an exciting podium presentation! Come visit us at Booth #8 to explore how the MERSCOPE Ultra? Platform, powered by MERFISH technology, delivers comprehensive spatial analysis of complex biology at sub-cellular resolution. ?? Don’t Miss Our Podium Presentation: ?? Date: November 22, 2024 ? Time: 10:00 - 10:30 AM SGT ?? Topic: Mapping the Future of Spatial Genomics with MERSCOPE Ultra? and MERFISH 2.0 ?? Presenter: Paul Rasmussen, Regional VP of Sales (APAC) Plus, join us for a groundbreaking research talk: ?? Spatio-temporal Analysis of Microglia Form and Functions in Human Brain Immune Organoids ?? Presented by: Satish Kumar Tiwari, Ph.D., Scientist, Singapore Immunology Network- SIgN ?? Don’t forget to visit the Vizgen & Genomax Technologies team at Booth #8. See you at the forefront of spatial biology innovation! #SpatialBiology #MERSCOPEUltra #MERFISH

?? The 2nd Spatial Biology Congress Asia (Global Engage) is Almost Here! ?? We’re thrilled to announce that Vizgen will be exhibiting at this year’s event and presenting an exciting podium presentation! Come visit us at Booth #8 to explore how the MERSCOPE Ultra? Platform, powered by MERFISH technology, delivers comprehensive spatial analysis of complex biology at sub-cellular resolution. ?? Don’t Miss Our Podium Presentation: ?? Date: November 22, 2024 ? Time: 10:00 - 10:30 AM SGT ?? Topic: Mapping the Future of Spatial Genomics with MERSCOPE Ultra? and MERFISH 2.0 ?? Presenter: Paul Rasmussen, Regional VP of Sales (APAC) Plus, join us for a groundbreaking research talk: ?? Spatio-temporal Analysis of Microglia Form and Functions in Human Brain Immune Organoids ?? Presented by: Satish Kumar Tiwari, Ph.D., Scientist, Singapore Immunology Network- SIgN ?? Don’t forget to visit the Vizgen team at Booth #8. See you at the forefront of spatial biology innovation! #SpatialBiology #MERSCOPEUltra #MERFISH

?? Opening New Doors in #SpatialBiology: 3 Stages of Mouse Embryo Development Captured in a Single MERSCOPE Ultra? Run! With MERSCOPE Ultra, you can now analyze three stages of whole mouse embryos (E10, E12, and E14) all on a single slide—eliminating batch effects and other experimental variations, ensuring consistent and reliable results. ?? Key Metrics: ?Total Area Imaged: 116 mm2 ?Total Cells: 612,764 ?Total Transcripts: 255,473,213 ?Panel Used: 500 Gene Embryo Panel ?Imaging Time: 27hrs &18 min Our groundbreaking platform enables complex biology at unprecedented detail, with seamless data you can trust. ?? Discover how MERSCOPE Ultra can transform your research- https://hubs.ly/Q02YwGGr0 #SpatialTranscriptomics #MERSCOPEUltra #Vizgen #SpatialBiology

??Our Global Engage #Webinar in partnership with the Earlham Institute is tomorrow. Last chance to register! ??? 15 November 2024 | Friday | 09:00 AM GMT | ? 75 Minutes #SpatialTranscriptomics is a powerful tool for measuring and mapping gene activity. In this webinar, experts from the Earlham Institute will share their journey working with the Vizgen MERSCOPE?, offer tips for optimizing the platform for tricky samples (e.g., wheat and megakaryocytes), and discuss their expertise. ???Webinar Speakers: ?Iain Macaulay, Technical Development Group Leader ?Ashleigh Lister, Senior Research Assistant ?Sonia Fonseca, Postdoctoral Research Scientist ? Moderated by: Carole Chedid, Field Application Scientist, Vizgen ??Register now- https://hubs.ly/Q02Y16RB0 ??Register to access the webinar on-demand after the event! #SpatialTranscriptomics #MERSCOPE #Webinar #Vizgen #EarlhamInstitute #Genomics