Society for Basic Urologic Research | SBUR

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Congratulations to Krinio Giannikou, PhD, from UCSD for her SBUR Travel Award and podium presentation! "The awarded poster highlighted our recent work on TSC1-mutant bladder cancer (TSC1mBLCA), which is a distinct molecular subtype with a gene expression profile mirroring syndromic TSC tumors. We demonstrated that nuclear TFE3 drives tumor growth and lysosomal dysfunction, highlighting TFE3 as a key therapeutic target, while bi-steric mTORC1 inhibitors effectively reduce tumor proliferation without disrupting TFE3 activity. Receiving this award and attending the meeting has been invaluable for networking and engaging with leaders in the field, which has significantly contributed to my growth and aspirations in urology research."

Congratulations to Sander Frank, PhD, SBUR Travel Awardee, from the Fred Hutchinson Cancer Center! "Our poster focused on trying to better understand the consequences of CDK12 mutation in advanced prostate cancer and identify effective and targeted therapeutic strategies. We analyzed patient tumor sequencing data and developed new cell models which revealed cells adapted to CDK12 loss display a different phenotype than expected, helping to explain why patients have not shown good responses to PARP inhibitors as would be predicted. The SBUR travel award helped to highlight a project that took many years of hard work. Attending the 2024 SBUR meeting allowed me to meet up with new and established collaborators to foster cooperation and stay abreast of the latest research in our field."

We are thrilled to introduce our first trainee Travel Awardee, Gada Awdalkreem, MBBS, MSc. Here is how she described her research: "Our poster effectively elucidated the development of the NEPC cell line derived from androgen -sensitive MyC-CaP cell line, it highlighted the intricate processes involved in in vitro treatment and subsequent passages in a syngeneic FVB mice model under ADT therapy, along with the characterization through histological diagnosis and the molecular signature of the NPEC tumors. I was deeply honored to receive the 2024 travel award from the SBUR committee, which served as a remarkable acknowledgment of our advanced work. Participating in the SBUR conference not only allowed me to present our research but also to introduce myself to esteemed clinicians and scientists specializing in Urology, particularly in NEPC tumors. This experience facilitated valuable collaborations, expanded my professional network, and provided exposure to cutting-edge research in the field." Congratulations! We hope to welcome you back at our next meeting!

Congratulations to all the 2024 SBUR Fall Meeting Travel Award Winners! Over the coming weeks, we'll be featuring each awardee's exciting research. Stay tuned!

Save the date! The SBUR 2025 Annual Meeting will be here before you know it.

Join us for Emerging Therapeutic Approaches in the Management of Urologic Disease at #SBUR2024!

The #SBUR2024 Business Meeting is wrapping up!

Learn more about Genetic and Endocrine Basis of Urologic Disease at #SBUR2024!

Join us for Transcriptional Subtypes of Urologic Disease—now at #SBUR2024!