UpToDate

Read our Expert Insight to discover how pharmacogenomic testing transforms cardiovascular care, enhancing patient safety, tailoring drug therapies, and cutting costs. https://ow.ly/50Iy50V8to9 #UpToDate #ChiefMedicalOfficer #pharmacogenomics #cardiovascularcare #drugtherapy

In a study of sugar rationing in the United Kingdom after World War II, reduced sugar consumption during the first two years of life decreased the risk of type 2 diabetes, hypertension, and obesity in adulthood by 20 to 35 percent. These findings expand the evidence of "metabolic programming" and demonstrate that limiting sugar exposure during the first two years of life has important long-term health benefits. Stay #UpToDate with What's New in #pediatrics: https://ow.ly/vOPY50VkXkA #ClinicalUpdates #meded

Yesterday’s #ClinicalChallenge question was: At what age should healthy adults start to be offered the pneumococcal vaccine? A. 50 years B. 60 years C. 65 years ?? The correct answer is: A. 50 years In October 2024, the United States Advisory Committee on Immunization Practices (ACIP) extended pneumococcal vaccination recommendations to include all adults ≥50 years of age, regardless of risk factors. Previously, the age threshold was ≥65 years for healthy adults and ≥19 years for those at risk for pneumococcal infection or severe complications from pneumococcal infection. This decision is based on knowledge that the incidence of pneumococcal disease starts to increase at age 50 years and the predicted reduction in invasive pneumococcal disease cases in certain underrepresented ethnic/racial groups within the United States. We agree with the new guidelines from the ACIP and now suggest pneumococcal vaccination beginning at age 50 years for all adults. View the related What's New topic in #UpToDate: https://ow.ly/TPPf50VaiiK #PrimaryCare #meded

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Before choosing a clinical #AI solution, make sure it is built on a framework of rigorous review and continuous advancement. Manish Vazirani, Vice President of Clinical Effectiveness Product Software Engineering for Wolters Kluwer Health, recommends reviewing clinical #GenAI tools against a checklist of four pillars of trust. Find out what they are: https://ow.ly/Ux6u50V8mUf #HealthcareAI #clinicaldecisionsupport

The FDA has approved an expanded indication for Neffy (epinephrine) nasal spray for the treatment of type I allergic reactions, including anaphylaxis, in adults and children 4 years and older weighing 15 kg or more. Check out our drug referential resources: ??https://ow.ly/tnhU50VfP9N ??https://ow.ly/OmE050VfP9Q #DrugNews #Pharmacy #Medication

Midland Health, known for its dedication to patient care and clinical advancement has adopted UpToDate Enterprise Edition. Dr. Rohith Saravanan, Chief Medical Officer at Midland Memorial Hospital, has used #UpToDate throughout his medical career, so our #clinicaldecisionsupport solution was a natural fit for the organization. Learn more: https://ow.ly/Wy8b50V8pmA #UpToDate #HealthcareAI

Radical cystectomy causes significant bleeding.?Prophylactic tranexamic acid (TXA) reduces blood loss during some types of surgery, but in a randomized trial of 386 patients undergoing open radical cystectomy for bladder cancer, TXA did?not?reduce 30-day blood transfusion rate, blood loss, or intraoperative blood transfusion rate compared with placebo. Based on these findings, prophylactic TXA should not be used for open radical cystectomy. Stay #UpToDate with What's New in #surgery: https://ow.ly/FJtK50VcKeJ #ClinicalUpdates #meded

Yesterday’s #ClinicalChallenge question was: All of the following are preferred antibiotic options for the initial treatment of Helicobacter pylori infection except: A. Clarithromycin-based regimens B. Bismuth quadruple therapy C. Rifabutin triple therapy D. Vonoprazan-amoxicillin dual therapy ?? The correct answer is: A. Clarithromycin-based regimens Recent guidelines from the American College of Gastroenterology emphasize the importance of using nonclarithromycin-based regimens for the initial treatment of H. pylori infection. View the related What's New topic in #UpToDate: https://ow.ly/ibsE50VahYS #gastroenterology #meded

The insights and connections forged at HIMSS 2025 will continue to fuel innovation across the industry. Wolters Kluwer remains committed to pushing boundaries and delivering solutions that inspire trust, elevate patient care, and transform healthcare for the better—learn how our healthcare solutions can support your organization in shaping the future of care. https://ow.ly/QrZo50Vh08X #HealthcareAI #HIMSS25