UpToDate

Midland Health, known for its dedication to patient care and clinical advancement has adopted UpToDate Enterprise Edition. Dr. Rohith Saravanan, Chief Medical Officer at Midland Memorial Hospital, has used #UpToDate throughout his medical career, so our #clinicaldecisionsupport solution was a natural fit for the organization. Learn more: https://ow.ly/Wy8b50V8pmA #UpToDate #HealthcareAI

Radical cystectomy causes significant bleeding.?Prophylactic tranexamic acid (TXA) reduces blood loss during some types of surgery, but in a randomized trial of 386 patients undergoing open radical cystectomy for bladder cancer, TXA did?not?reduce 30-day blood transfusion rate, blood loss, or intraoperative blood transfusion rate compared with placebo. Based on these findings, prophylactic TXA should not be used for open radical cystectomy. Stay #UpToDate with What's New in #surgery: https://ow.ly/FJtK50VcKeJ #ClinicalUpdates #meded

Yesterday’s #ClinicalChallenge question was: All of the following are preferred antibiotic options for the initial treatment of Helicobacter pylori infection except: A. Clarithromycin-based regimens B. Bismuth quadruple therapy C. Rifabutin triple therapy D. Vonoprazan-amoxicillin dual therapy ?? The correct answer is: A. Clarithromycin-based regimens Recent guidelines from the American College of Gastroenterology emphasize the importance of using nonclarithromycin-based regimens for the initial treatment of H. pylori infection. View the related What's New topic in #UpToDate: https://ow.ly/ibsE50VahYS #gastroenterology #meded

The insights and connections forged at HIMSS 2025 will continue to fuel innovation across the industry. Wolters Kluwer remains committed to pushing boundaries and delivering solutions that inspire trust, elevate patient care, and transform healthcare for the better—learn how our healthcare solutions can support your organization in shaping the future of care. https://ow.ly/QrZo50Vh08X #HealthcareAI #HIMSS25

?? #ClinicalChallenge #gastroenterology #meded All of the following are preferred antibiotic options for the initial treatment of Helicobacter pylori infection except: A. Clarithromycin-based regimens B. Bismuth quadruple therapy C. Rifabutin triple therapy D. Vonoprazan-amoxicillin dual therapy ??Please add your answer to the comments.

The future of healthcare lies in strategic collaboration. By partnering with forward-thinking organizations, Wolters Kluwer will continue to deliver high-impact solutions addressing the industry’s most pressing challenges. But our commitment extends beyond innovation—it’s about driving real value for hospital systems, clinician care teams, and patients. Our focus will continue to be on bringing our unmatched expertise and trusted content together with industry collaborators, to deliver value and innovation. Together with Abridge, Corti, Lumeris, Microsoft, Phrase Health, Suki, Wellsheet and ZeOmega and more, we are reshaping the healthcare landscape. https://ow.ly/fQ5550VgZOi

On #WorldKidneyDay, let's raise awareness about kidney health and the importance of early detection. Together, we can take steps toward preventing chronic kidney disease and supporting those affected. https://ow.ly/M8wp50VgZCa #UpToDateSupportsHealth #KidneyHealth #EarlyDetection #CKDAwareness

In patients with transthyretin (ATTR) cardiac amyloidosis, one option for therapy is?RNA interference, which?reduces?hepatic production of transthyretin. In a placebo-controlled trial?in >650 patients with ATTR cardiac amyloidosis, vutrisiran, an RNA interference agent, reduced mortality and?heart failure (HF)?events after?36 months without increasing adverse events.? In those with ATTR cardiac amyloidosis and NYHA class I to III HF symptoms, we recommend tafamidis, acoramidis, or vutrisiran. Stay #UpToDate with What's New in #cardiology: https://ow.ly/Zn5s50VcK03 #ClinicalUpdates #meded

Yesterday’s #ClinicalChallenge question was: True or false? Small-bore chest tubes may be appropriate for selected patients with traumatic hemothorax. ?? The correct answer is: True. In a systematic review of studies comparing large-bore tubes (≥20 Fr) with small-bore tubes (≤14 Fr) for traumatic hemothorax in adults, the pooled failure rate (ie, incompletely drained or retained hemothorax requiring a second intervention) was similar for both groups. View the related What's New topic in #UpToDate: https://ow.ly/4Wq350VahFn #surgery #meded

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