UpToDate

Yesterday’s #ClinicalChallenge question was: All of the following are preferred antibiotic options for the initial treatment of Helicobacter pylori infection except: A. Clarithromycin-based regimens B. Bismuth quadruple therapy C. Rifabutin triple therapy D. Vonoprazan-amoxicillin dual therapy ?? The correct answer is: A. Clarithromycin-based regimens Recent guidelines from the American College of Gastroenterology emphasize the importance of using nonclarithromycin-based regimens for the initial treatment of H. pylori infection. View the related What's New topic in #UpToDate: https://ow.ly/ibsE50VahYS #gastroenterology #meded

The insights and connections forged at HIMSS 2025 will continue to fuel innovation across the industry. Wolters Kluwer remains committed to pushing boundaries and delivering solutions that inspire trust, elevate patient care, and transform healthcare for the better—learn how our healthcare solutions can support your organization in shaping the future of care. https://ow.ly/QrZo50Vh08X #HealthcareAI #HIMSS25

?? #ClinicalChallenge #gastroenterology #meded All of the following are preferred antibiotic options for the initial treatment of Helicobacter pylori infection except: A. Clarithromycin-based regimens B. Bismuth quadruple therapy C. Rifabutin triple therapy D. Vonoprazan-amoxicillin dual therapy ??Please add your answer to the comments.

The future of healthcare lies in strategic collaboration. By partnering with forward-thinking organizations, Wolters Kluwer will continue to deliver high-impact solutions addressing the industry’s most pressing challenges. But our commitment extends beyond innovation—it’s about driving real value for hospital systems, clinician care teams, and patients. Our focus will continue to be on bringing our unmatched expertise and trusted content together with industry collaborators, to deliver value and innovation. Together with Abridge, Corti, Lumeris, Microsoft, Phrase Health, Suki, Wellsheet and ZeOmega and more, we are reshaping the healthcare landscape. https://ow.ly/fQ5550VgZOi

On #WorldKidneyDay, let's raise awareness about kidney health and the importance of early detection. Together, we can take steps toward preventing chronic kidney disease and supporting those affected. https://ow.ly/M8wp50VgZCa #UpToDateSupportsHealth #KidneyHealth #EarlyDetection #CKDAwareness

In patients with transthyretin (ATTR) cardiac amyloidosis, one option for therapy is?RNA interference, which?reduces?hepatic production of transthyretin. In a placebo-controlled trial?in >650 patients with ATTR cardiac amyloidosis, vutrisiran, an RNA interference agent, reduced mortality and?heart failure (HF)?events after?36 months without increasing adverse events.? In those with ATTR cardiac amyloidosis and NYHA class I to III HF symptoms, we recommend tafamidis, acoramidis, or vutrisiran. Stay #UpToDate with What's New in #cardiology: https://ow.ly/Zn5s50VcK03 #ClinicalUpdates #meded

Yesterday’s #ClinicalChallenge question was: True or false? Small-bore chest tubes may be appropriate for selected patients with traumatic hemothorax. ?? The correct answer is: True. In a systematic review of studies comparing large-bore tubes (≥20 Fr) with small-bore tubes (≤14 Fr) for traumatic hemothorax in adults, the pooled failure rate (ie, incompletely drained or retained hemothorax requiring a second intervention) was similar for both groups. View the related What's New topic in #UpToDate: https://ow.ly/4Wq350VahFn #surgery #meded

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As the healthcare industry increasingly engages with food as medicine, #payers can support dietary #caremanagement programs with a focus on #nutrition. Find out more: https://ow.ly/5SbV50VcMXF #foodasmedicine #membereducation

A new meta-analysis including over 17,000 college athletes and military recruits reported that 31 percent had iron deficiency (ferritin <30 ng/mL). Female athletes/recruits were more likely to be affected than male athletes/recruits; prevalence was similar in those <18 versus ≥18 years of age. These observations confirm that high-intensity physical training is a significant risk factor for iron deficiency and support a role for screening in this population. Stay #UpToDate with What's New in #hematology: https://ow.ly/fZOI50VcJPF #ClinicalUpdates #meded