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?? #ClinicalChallenge #EmergencyMedicine #meded Which is true regarding the Society of Academic Emergency Medicine guidelines for the treatment of vomiting and severe abdominal pain due to cannabinoid hyperemesis syndrome? A. Intravenous fluids and standard antiemetics usually manage symptoms. B. In addition to usual care, give dopamine antagonists (e.g., droperidol or haloperidol) for symptom management; patients at risk for QT prolongation should have an electrocardiogram obtained prior to administration. C. Apply capsaicin cream to the abdomen for all patients. D. Give opioid analgesia to patients with severe abdominal pain. ??Please add your answer to the comments.?

The respiratory syncytial virus (RSV) vaccine is recommended for immunocompromised individuals aged 60 and above despite limited data. In an electronic health records-based observational study that included over 10,000 predominantly mild to moderately immunocompromised individuals ≥60 year olds, vaccine effectiveness was 73 percent against RSV-associated hospitalization at follow-up of one year. This study supports vaccination against RSV in immunocompromised individuals aged 60 and above. Stay #UpToDate with What's New in #InfectiousDiseases: https://ow.ly/VsNM50UebZr #ClinicalUpdates #meded

The FDA has approved Kebilidi (eladocagene exuparvovec-tneq) suspension for intraputaminal infusion. Kebilidi is indicated for the treatment of adult and pediatric patients with aromatic L-amino acid decarboxylase deficiency. For all the latest drug news, check out our drug referential resource: https://ow.ly/C8X150UcTut #DrugNews #Medication #Pharmacy

Yesterday’s #ClinicalChallenge question was: True or false? For Sydenham chorea, use of glucocorticoids is associated with faster resolution of chorea. The answer is: True. In a recent meta-analysis of observational studies on Sydenham chorea (SC) outcomes published from 1945 through 2022, median chorea duration was shorter for patients who received ≥1 month of glucocorticoids compared with no glucocorticoids (1.2 versus 2.8 months), and the rate of adverse events was low. These data, along with results of a single small, randomized trial, support use of glucocorticoids in patients with moderate to severe SC. A typical regimen is prednisone 1 to 2 mg/kg daily for two weeks and then tapered over two to three weeks. View the related What's New topic in #UpToDate: https://ow.ly/38br50TYmJx #neurology #meded

Last week, Amanda Heidemann MD, FAAFP, FAMIA, Physician Advisor for UpToDate, was selected for the 2025 class of Fellows of the American Medical Informatics Association. A formal induction ceremony will be held at the AMIA (American Medical Informatics Association) 2025 Clinical Informatics Conference in May. Congratulations, Amanda!

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Krankenh?user haben eine Zukunft – und Künstliche Intelligenz (#KI) wird darin zunehmend eine Rolle spielen: Das war ein Tenor beim Think Tank von Wolters Kluwer Health in Berlin. Unter dem Motto ?Gesundheit – neu gestalten“ brachte er Führungskr?fte aus der Branche zusammen. Das Ziel lautete, plausible Handlungsfelder für Krankenh?user zu identifizieren – in einer Zeit, die von einem weitreichenden Wandel in der Leistungserbringung gepr?gt ist. Um sich mit ihren vielversprechenden Nutzenpotenzialen durchzusetzen, muss KI Vertrauen schaffen. Zu den Voraussetzungen für Akzeptanz bei Mitarbeitenden und Patient:innen z?hlt, dass Daten für das Trainieren der L?sungen valide sind und insbesondere Bias vermeiden, etwa im Hinblick auf das Geschlecht. ? Die Beschleunigung von Prozessen, ? die Erh?hung von #Behandlungsqualit?t und #Patientensicherheit ? sowie die Optimierung der Effizienz bei der Ressourcennutzung sind Vorteile, die Krankenh?usern die Neupositionierung im Wandel erleichtern. Patientenversorgung, Verwaltung, Management und Forschung bieten sich als Anwendungsbereiche an. Der Return on Invest muss für diese Technologien noch belegt werden. Ein konkreter Use Case ist die Einbindung von KI-Technologie in Systeme zur Unterstützung klinischer Entscheidungen. Diese L?sungen, mit denen Mitarbeitende die Flut an neuen Erkenntnissen meistern k?nnen, werden künftig dank KI noch leistungsst?rker und nutzerfreundlicher, wie Garry Edwards in seinem Vortrag “How clinical decision support technology is evolving around the world“ eindrücklich erl?uterte. Unter den weiteren Handlungsspielr?umen für Krankenh?user waren die #Ambulantisierung von Leistungen und regionale Kooperationen. Die Teilnehmenden zeigten sich inspiriert für ihre t?gliche Arbeit – und sie freuen sich auf die n?chste Auflage des Think Tanks im kommenden Jahr. Wolters Kluwer Health dankt Dr. Alina Dahmen, M.Sc., und Dr. med. Peter Gocke für die Teilnahme am Impulsdialog, Dr. Karin Hochbaum, Jens Schneider und Prof. Dr. med. Kai Wehkamp für spannende Berichte aus der Praxis, Volker Nürnberg (Prof. Dr.) und Simone Mahn für die exzellente Moderation sowie allen Teilnehmenden für wichtige Einblicke und interessante Diskussionsbeitr?ge. #GesundheitNeuGestalten #Krankenhausmanagement #Entscheidungsunterstützung #UpToDate

In a study of 42 individuals with acute thrombotic thrombocytopenic purpura (TTP) who had an initial response to caplacizumab and omitted plasma exchange, outcomes were comparable to a group of 59 individuals who received caplacizumab plus plasma exchange.? While experts continue to recommend plasma exchange for all patients with TTP, this study provides reassurance that selected individuals with a rapid response to caplacizumab may omit plasma exchange. Further study of this approach is ongoing. Stay #UpToDate on What's New in #hematology: https://ow.ly/IVoc50TYwrH #ClinicalUpdates #meded

We had the privilege to participate in the 7th GCC eHealth Workforce Development Conference in Dubai, where many #healthcare leaders and advocates in the region discussed the future of #patientsafety, #virtualcare and value based healthcare. #eHWDC24 #GCCeHealth2024 #eHealthConference2024 #MWANEvents

Yesterday’s #ClinicalChallenge question was: Which is true regarding cervical spine injury in children with blunt trauma? A. Mechanism of injury, more often than clinical findings, determines the need for cervical spine imaging B. Children with neck pain or tenderness after blunt trauma should have cervical spine imaging C. All children with blunt trauma should undergo cervical spine imaging D. Children with a Glasgow Coma Scale score <14 should undergo computed tomography of the cervical spine The answer is: B. A clinical prediction rule based on nine clinical findings can identify the risk of cervical spine injury in children with high sensitivity, specificity, and negative predictive value and help guide imaging decisions. Children at low risk by this rule (awake and alert, no neck pain or tenderness, and no serious head or torso injury) do not require cervical spine imaging; C-spine CT is the initial study advised for children with abnormal airway, breathing or circulation; coma; or a focal neurologic deficit. View the related What's New topic in #UpToDate: https://ow.ly/8vcH50TYmE4 #EmergencyMedicine #meded