TriLink BioTechnologies, part of Maravai LifeSciences

Japanese researchers have developed a method for pH-modified spray freeze-drying of mRNA-LNPs that could be used for producing dry powder mRNA-LNP inhalers. Learn how TriLink’s?CleanCap??AG?facilitated this breakthrough in our latest Research Spotlight. #research #innovation #RNA #mRNA

?? Big science, small mic—welcome to our?first-ever Mini Mic video! ? We’re putting the spotlight on two key players behind our latest discovery mRNA offering, Emma Rosen and Cameron G.! From inspiration to innovation, they share the impact and excitement of the ???????????? ???????? ???? ???????? ?????? ?????????????? ????????????, designed to accelerate your screening and hit-to-lead optimization studies. ? #MiniMicInterview #mRNA #ProductLaunch #Biotech

In a recent article from Genetic Engineering & Biotechnology News, Kevin Lynch, VP/GM of GMP operations discusses how TriLink BioTechnologies, part of Maravai LifeSciences's optimized workflows and in-process controls are setting new standards for mRNA manufacturing.? ??The article highlights TriLink and other innovators driving advancements in mRNA manufacturing showcasing the industry’s collective efforts to meet growing demand and ensure product quality.? Read more about the article here: https://lnkd.in/et_daJTK #mRNA #manufacturing #Biotech

This week, we had the privilege of hosting a gathering of innovators, executives, and thought leaders in the mRNA field during our customer event at The Tower in Boston. ? From engaging conversations to meaningful connections, the evening was filled with inspiring moments that truly showcased the collective passion and innovation driving the future of mRNA technologies. We are incredibly grateful for the opportunity to bring together such a dynamic group of experts to continue important conversations from the mRNA Health conference, exchange insights, and explore new possibilities for collaboration. ? A heartfelt thank you to all who attended and contributed to making this event such a success. Your vision, expertise, and dedication inspire us to keep pushing the boundaries of what’s possible in the world of mRNA. ? Here’s to the partnerships and innovations that will shape the future—together! #mRNA #thoughtleaders #customerevent

Are you attending mRNA Health in Boston?? ?? Would you like to learn more about the innovative new products and services TriLink has launched over the past year to help accelerate your mRNA research and discovery?? Visit our team at booth 13. ? ?? Are you intrigued by the data shared this morning about our novel dsRNA-reducing RNA polymerase? Discuss with Stephanie Ramos, Ph.D., TriLink's VP of RD, at poster 120 ???????????????? ????, ??:???? - ??:???? ????. ? TriLink's scientists are looking forward to connecting with you at their posters! ? ?? Poster Presentation Details: ???????????????? ????, ??:???? ???? - ??:???? ???? o Utilizing DNAzyme Cleavage at the 3’ UTR for the Development of Various mRNA Analysis Techniques| Presented by Camila Ortega Ph.D. | Poster 37 ???????????????? ????, ??:???? ???? - ??:???? ???? o Development of a streamlined LC-HRMS/MS-based workflow for identification of mRNA sequence | Presented by Camila Ortega Ph.D. | Poster 36 o CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA | Presented by Benjamin Hudson | Poster 42 o A novel RNA polymerase variant for reduced dsRNA byproducts in mRNA manufacturing | Presented by Stephanie Ramos | Poster 120?

Guten Tag from our TriLink BioTechnologies, part of Maravai LifeSciences team attending TIDES in Hamburg. We are waiting for you at booth #402! Discover our comprehensive solutions designed for every stage of your drug development journey. From complex oligonucleotide synthesis and phase-appropriate #mRNA manufacturing to advanced nucleic acid analytics and custom #genomic tools, we have the expertise and resources to advance your projects. #RNA #dreamteam

Our team is excited to be showcasing four innovative posters this week at mRNA Health, highlighting our latest breakthroughs and advancements in mRNA research! ?? Poster Presentation Details: ???????????????? ????, ??:???? ???? - ??:???? ???? o Utilizing DNAzyme Cleavage at the 3’ UTR for the Development of Various mRNA Analysis Techniques| Presented by Camila Ortega Ph.D. | Poster 37 ???????????????? ????, ??:???? ???? - ??:???? ???? o Development of a streamlined LC-HRMS/MS-based workflow for identification of mRNA sequence | Presented by Camila Ortega Ph.D. | Poster 36 o CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA | Presented by Benjamin Hudson| Poster 42 o A novel RNA polymerase variant for reduced dsRNA byproducts in mRNA manufacturing | Presented by Stephanie Ramos | Poster 120 We’re excited to showcase our work and connect with you. See you soon! #mRNAHealth #mRNA #Innovation #Biotech

Attending the 12th International mRNA Health Conference in Boston? Look out for a presentation by TriLink BioTechnologies, part of Maravai LifeSciences's Stephanie Ramos, PhD, Vice President of Biology, as she dives into a novel RNA polymerase that reduces double-stranded RNA (dsRNA) by up to 85% with simple IVT integration. Reducing dsRNA is desirable in mRNA synthesis since dsRNA can impair the tolerability, safety, and potency of mRNA vaccines and therapeutics. ? Stephanie will also highlight the simplicity of substituting wild-type T7 RNA Polymerase with this novel enzyme to achieve dsRNA reduction without compromising IVT yields, capping efficiency, and mRNA integrity. Mark your calendar for her presentation's date and time to learn more about it. ? ?? Date: November 12, 2024 ?? Time: 10:15am ? We look forward to meeting you in Boston! ? #mRNAHealth #dsRNA #manufacturing #mRNAmanufacturing #mRNA

Maravai has announced its planned acquisition of the DNA and RNA business of Officinae Bio, a provider of precision DNA and RNA design services through an AI-driven digital platform. The mRNA, Gene Editing, along with the Cell and Gene therapy markets continue to evolve rapidly, and we remain committed to being our customers’ preferred partner by delivering innovative solutions to address critical barriers, increase process efficiency and improve potency and efficacy. Read the full press release here: https://lnkd.in/g7mNN4jH #mRNA #geneediting #therapeutics #acquisition

Find out how a team of researchers at the UMass Chan Medical School has been able to increase the level of dNTPs in order to improve prime editing efficiency. Their publication in Nature Portfolio Communications uses a functional variety of in vitro transcribed (IVT) mRNAs each synthesized with TriLink’s CleanCap? cap analog and N1-methylpseudouridine-5'-triphosphate (m1Ψ-5’-TP). #research #innovation #RNA #mRNA