Translating Aging

We’re gratified to see Translating Aging at the top of the list of aging & longevity podcasts at AgingBiotech.info. Many thanks to our friend Karl R. Pfleger for compiling and updating this incredible resource for anyone seeking to learn more about the latest in geroscience and longevity biotech. As we gear up for the 2024 season — our fourth! — now is a great time to check out our back episodes. (Our most recent show, an interview with aging pioneer Cynthia Kenyon, is a good place to start for newcomers seeking historical background on our field!) New content coming soon, so make sure you're subscribed. Thanks for listening! https://lnkd.in/gb9x5pYe

This week we talk with Markus Gst?ttner, CEO of clock.bio, a company devoted to extending and improving the quality of life by reversing the harmful effects of time in our cells. In this episode, Gst?ttner shares how his company is working to extend healthspan by understanding and harnessing the natural rejuvenation capabilities of stem cells. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases. Episode: https://lnkd.in/g2j7STw2 (click ‘FOLLOW’ on the episode page for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka

This week we talk with the founders of Arda Therapeutics, a biotechnology company developing novel therapies to selectively eliminate harmful cell populations driving chronic diseases. In this episode, CEO Adam Freund and CTO Remi-Martin Laberge discuss their innovative approach to treating illnesses by identifying and removing specific pathogenic cell types — rather than trying to modify cellular behavior through traditional drug-based approaches. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases. Episode: https://lnkd.in/gMhQ9sTf (click ‘FOLLOW’ for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka

“We're opening up the epigenome as a platform for drug discovery.” Moonwalk Biosciences is a biotech company devoted to pioneering precision epigenetic medicines. This week on Translating Aging, CEO & co-founder Alex Aravanis MD PhD tells us about Moonwalk’s mission to harness the power of epigenetics to develop a new class of medicines aimed at treating complex diseases and potentially extending human healthspan. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases. Episode: https://lnkd.in/g6XtThZK (click ‘FOLLOW’ for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka

“We believe every human has the right to live a longer, healthier life.” The Hevolution Foundation is a global non-profit organization that funds research and entrepreneurship in healthspan science, and has already become a major force in the field. This week on Translating Aging, Hevolution CEO Mehmood Khan tells the story of the foundation’s origins, its mission, and his vision for how the science of aging can revolutionize health care around the world. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases. Episode: https://lnkd.in/g3Jw4tyc (click ‘FOLLOW’ for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka

In this week's episode, Hans Keirstead of Immunis, Inc. shares how his company is developing novel secretome-based therapeutics to restore youthful immune function, with the goal of treating a wide range of age-related conditions — including muscle loss and obesity — while extending overall healthspan. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases. ??: Episode: https://lnkd.in/gesMqMgX Links to the major podcast platforms:? ? Apple Podcasts:?https://lnkd.in/gg-9m8H7 ? Google Podcasts: https://lnkd.in/gBm4zft9 ? Spotify: https://lnkd.in/ge4wzJPY

Age-related decline in ovarian function leads to adverse health outcomes. In this episode, Daisy Robinton, PhD tells us how her company Oviva Therapeutics is aiming to extend women’s healthspan through developing novel therapeutics that target ovarian function and longevity. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases. Episode: https://lnkd.in/gv7Aqf9A (click ‘FOLLOW’ for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka

Chronic diseases are the leading causes of death and disability in America, and they are also a leading driver of healthcare costs. In this episode, Dr. Noah Davidsohn, CSO and co-founder of Rejuvenate Bio, describes his company’s gene therapy approach to treating chronic age-related disease. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases. Episode: https://lnkd.in/gghfCYCg (click ‘FOLLOW’ for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka

Thirty years ago this week, Cynthia Kenyon published a groundbreaking paper entitled “A C. elegans mutant that lives twice as long as wild type”—revealing that lifespan is under genetic control. That study, along with others published around the same time, have led some observers of the field to identify the early 90s as the dawn of the modern biology of aging. In this episode, Dr. Kenyon shares her perspective on how our field has grown and changed over the past three decades. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company?developing drugs to treat human disease and extend healthspan by targeting the molecular mechanisms of aging. Episode: https://lnkd.in/gnYSeHWV (click ‘FOLLOW’ for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka

Today, XPRIZE launched its largest-ever competition - a $101 million prize for a team that can develop a therapeutic that restores muscle, cognition, and immune function by at least 10 years. In this episode, we talk with Jamie Justice, Ph.D., Executive Director of XPRIZE Healthspan, about? the motivation, structure, and timeline of the prize—as well as how teams can get involved. Translating Aging is produced by BioAge Labs, a clinical-stage biotechnology company?developing drugs to treat human disease and extend healthspan by targeting the molecular mechanisms of aging. Episode: https://lnkd.in/gJGXRfeR (click ‘FOLLOW’ for links to your favorite podcast platform) Podcast: https://lnkd.in/gvF4X-ka