Translational Pulmonary and Immunology Research Center

??Exploring Breakthroughs in Food Allergy Diagnostics with Machine Learning ?? What's Inside Dive into this groundbreaking research detailing the development of a machine learning algorithm designed to predict anaphylaxis risk with over 95% accuracy! Using data from the Tolerance Induction Program (TIP), this model analyzes 241 allergy markers to provide patient-specific assessments, offering unprecedented precision for peanut allergy risk prediction. ?? Why It Matters Traditional diagnostic methods often lack accuracy, leaving patients vulnerable and treatment plans uncertain. This innovative approach leverages big data and advanced machine learning to transform how we evaluate and manage food allergies, making accurate, affordable diagnostics accessible to more families. ? Implications for the Food Allergy Community This work offers hope to millions managing life-threatening allergies. Beyond diagnostics, the potential for personalized treatment plans means improved safety, better outcomes, and a step closer to #FoodFreedom for patients everywhere. ?? Read More Curious about how TPIRC is reshaping food allergy care? Visit the link below to read more full research papers: https://lnkd.in/dbjmKgyP

Meet Isaac L., a young leader with an inspiring story! Isaac, a talented baseball pitcher (he struck out four players in a row ??), refuses to let his food allergies define him. For his bar mitzvah project, he raised $5750 to help another child begin their Journey to Food Freedom through the Food Allergy Institute. Isaac’s compassion and generosity remind us of the power of community and the hope we share for a brighter future. This Giving Tuesday, join Isaac in making a difference. Join our Food Freedom Challenge and help us match Isaac’s donation! Donate here: https://tpirc.org/

Isaac Lipton is 12 years old and already making an incredible impact. For his bar mitzvah project,? he’s raising funds to help another child start their journey to Food Freedom. This Giving Tuesday, we’re inspired by Isaac’s generosity and asking our community to match his donation. Let’s raise the bar together and make this life-changing program accessible to more families. ??Donate here: www.tpirc.org ?Please take a moment to read his story below: My name is Isaac Lipton. I'm 12 years old, and I have life-threatening tree nut allergies, including walnuts, cashews, pistachios, pecan, Brazil nuts, and hazelnuts. I also have a sensitivity to shellfish. I am trying to help another child participate in the Food Allergy Institute's Journey to Food Freedom, as I am fortunate to be able to. I discovered my allergies at 18 months and when my friends go out for food and ice cream, I am very limited in what I can have and sometimes feel left out. I am extremely fortunate to have found the Food Allergy Institute. Using individualized treatment plans and biosimilar food proteins, FAI helps me build tolerance before introducing anaphylactic allergens. That means I have to eat certain foods every day to prepare my body for when I introduce my anaphylactic allergens - it's a lot of work, but worth it! I also get to travel to California every 3 months which is expensive, but I would also say fun. I have passed hazelnut, mollusks, and lobster already and am partway through pistachio and pecan(passed cross-contamination). I have about a year left. Once I go through the program successfully, I can achieve Food Freedom and eat anything I want, including the nuts I am allergic to!! Wow - I can't wait!!! This has been a life-changing experience for me and I cannot be more grateful for the program. For my bar mitzvah project, I would like to raise money to help people who are less fortunate than me start the program and get the same opportunities as me. #GivingTuesday #Philanthropy #FoodAllergyAwareness #FoodFreedom #FoodAllergyInstitute #TPIRC

Philanthropy is at the core of our organizations. I started TPIRC over a decade ago as a non-profit. The early days of philanthropy involved a small team supporting a small organization. So many years later, our mission is consistent and core trust in philanthropy remains. Today, I want to recognize our small but mighty philanthropy team. They work so hard each day shining a bright light on FAI and TPIRC. They interact and travel across the country to build interest and drive donations to support the many programs which support so many patients. I hope you will join me in recognizing our great philanthropy team today. Thank you Aissatou and Maya! - Dr Randhawa- CEO Food Allergy Institute, TPRIC #TPIRC #foodallergyinstitute #rarediseases #research

TPIRC would like to welcome our newest board member,?Justin Webb, to the organization.?Justin Webb?has an extensive career in finance and investment. Starting as an Analyst and Trader at Lehman Brothers in 2004, he went on to co-found and manage PLW Investment Group, followed by roles at Macquarie Group and founding Helix Partners, which he sold to Ascalon Capital. He later founded PacWealth Capital and held leadership roles at BlackRock Australia and Tonnerre Investments. In 2014,?Justin?co-founded Agriwebb, serving as Executive Chairman. He holds degrees from Radley College, Harvard University, and an MBA from Oxford’s Said Business School. Last week, he toured the TPIRC facilities including the diagnostics with our COO, Anoop Lohara, and Peter Ngo, Aperture Diagnostics?lab manager. He also toured the TPIRC research labs with director, Dr. Nathan Marsteller. #TPIRC #Foodallergyinstitute #raredisease #research #allergies #anaphylaxis #philanthropy

?? Thrilled to share a moment from our recent ambassador dinner in New York! A huge thank you to all our ambassadors and attendees for making the evening a success. Pictured with me are David and Melissa Garcia! We highlighted the importance of raising awareness and support for orphan diseases, while emphasizing?TPIRC’s?mission to advance treatment discovery and leverage big data to unlock the mysteries of rare diseases. TPIRC has been instrumental in supporting the research and establishment of the Food Allergy Institute, enhancing our ability to provide effective treatments and restore hope to patients and families worldwide. Together, we can make a difference! If?you’re?interested in supporting our mission through philanthropy, please reach out. Let’s continue advocating for those who need it most! #OrphanDiseases?#Research #Diagnostics #MentalHealthAwareness?#TPIRC #Collaboration #HealthInnovation?#Support #Community #Awareness #Philanthropy #DonorSupport?#CureRareDiseases #FoodAllergyInstitute?#HopeAndHealth

Happy National Physician Assistant Week! ?? Today, we would like to give a warm shout-out to Sunny! Sunny is an invaluable member of our team, bringing her warmth into every interaction with our tiniest newborns to our college patients. Her dedication to supporting both the children and our physicians shines through in everything she does. With a gentle touch and a compassionate heart, she creates a nurturing environment that makes a world of difference in the lives of those she cares for. We are truly grateful for continuous commitment and the positive impact she has on our practice! Thank you Sunny! #tpirc #laha #rarediseases #foodallergyinstitute

Happy Research Appreciation Day!? "Today is Research Appreciation Day, and I want to express my thanks to the research team for their dedication to our mission. In our pursuit to understand the intricate cellular and molecular mechanisms underlying food allergy, bronchopulmonary dysplasia, cystic fibrosis, and other rare diseases, your dedication is evident and appreciated. Together, we delve into the depths of experimental design, implementation, and analysis, driven by a shared passion to make a tangible difference in the lives of those we serve. We’re making significant strides toward understanding these diseases and achieving food freedom for all FAI patients. Thank you for your hard work, passion, and commitment.” -Dr. Nathan Marsteller, Director of Research . . . #researchappreciationday #medicalresearch #rarediseases #foodallergyresearch #tpirc

Congratulations to TPIRC Board member Jim McDonnell, who was recently honored in the 2024 Twice A Citizen Awards. Jim McDonnell, former Sheriff of Los Angeles County and Long Beach Police Chief was recognized on Saturday, May 4th, for his extraordinary efforts “to protect and to serve” the citizens of Los Angeles above and beyond the call of duty. We want to take a moment to express our gratitude to Jim for his incredible contributions to safe-keeping our community and for his unwavering support of our mission to accelerate treatment discovery for rare diseases like food anaphylaxis. Thank you, and congratulations once again on this well-deserved honor! . . . #twiceacitizen #lapd #congratulations #rarediseases

Thank you, TPIRC Board Chair Paul Orlin, for hosting Dr. Randhawa, TPIRC, and the Food Allergy Institute at the Moise Safra Center in New York. We would also like to thank our Event Committee: Jaimee Bloom, Victoria Orlin, Rebecca Matchett, Melissa Garcia, Jonathan Durham (TPIRC Board Member), Dr. Rachel Sales, and everyone at the Moise Safra Center. It was so great to see everyone who came out to the event to support our mission to advance treatment discovery for rare diseases like food anaphylaxis. Your presence and support mean the world to us! Together, we are making a difference in the lives of those affected by severe food allergies. Let's continue to raise awareness and work towards a safer and more inclusive world for everyone. A special thanks to Maya McElroy for orchestrating this memorable event! . . . #FoodAnaphylaxisSupport #MoiseSafraCenterNYC #ThankYou #rarediseases #nyevents 2 / 2