Cultivated Meat Modeling Consortium

Are you curious about the CMMC? Take a look at this SHORT introduction to us and our work: Who we are. What we're doing. Why we're doing it. # #cultivatedmeat #cleanmeat #computermodeling #computationalbiology. #collaborativescience #wickedproblems #sustainablefood

?? Project Update: Pig-GEM – Optimizing Growth Media for Cultivated Pork Production The Pig-GEM Project addresses one of the toughest challenges in the cultivated meat industry: high growth media costs Growth media plays a crucial role in cell growth and yield, but the expenses make scaling cultivated meat production costly. Using computational modeling, Pig-GEM works to develop media formulations that enhance cell metabolism and in turn improve production efficiency. ?? Current Project Progress: ? New Model Developed: We’ve successfully created a computational model compatible with pig cells, enabling us to make precise predictions about cell growth ?? In-vitro Data Collected: Preliminary experiments have provided in-vitro data, validating the model's accuracy and its potential applications across the industry ?? Expanding Scope: We are now expanding the project to develop formulations for additional animal species —- creating more value for a range of players in the cultivated meat industry ?? Collaborations: The Pig-GEM team continues to work with academic experts and industry partners to ensure our models are practical and ready for commercial use. What’s Next??? We are creating models for additional animal species (including fish ??) and will be developing partnerships to support the model’s use across the cultivated meat sector. Adopting the use of the model can aid in reducing costs and optimizing processes. The team will perform experiments to ensure efficacy and Dr Nanette Nanette Boyle will be presenting the research related to this project at the International Scientific Conference on Cultured Meat on November 17-19, 2024. ?? Interested in learning more or collaborating? 1?? Comment below with your thoughts or questions. 2?? Tag someone who might find this relevant to their work. 3?? DM us or email [email protected] if you'd like to explore potential collaboration opportunities. ?? For more information, visit thecmmc.org.

???Sneak Peek: CMMC’s Latest Collaborations in Cultivated Meat Innovation!??? At the Cultivated Meat Modeling Consortium (CMMC), we’re thrilled to share a glimpse of two projects addressing critical challenges in cultivated meat production – and we’re doing it in collaboration with the talented team at the Colorado School of Mines and other leading experts! ???? ???Project 1:?Optimizing growth media formulations to reduce costs and improve production efficiency. ???Project 2:?Developing a bioreactor simulation toolkit to support better decision-making for yield and scalability. We’re looking forward to sharing more details soon on how these projects, with the expertise of our partners, are shaping the future of sustainable food production. Stay tuned! #CultivatedMeat #Innovation #AlternativeProtein #CMMC #ColoradoSchoolOfMines #SustainableFood #Collaboration

?? Proud to Support Pioneering Research in Cultivated Meat! ?? We’re thrilled to see this progress highlighted! Earlier in 2023, CMMC had the privilege of funding Dr. Nannette and her team’s pioneering work in developing the GEM model for porcine cells, advancing fat cell research for cultivated meat. This work is crucial in bringing authentic flavor and texture to cultivated pork, taking us a step closer to the future of sustainable food. Congratulations to Dr. Nannette Nanette Boyle, Sandra Itzel Gomez Romero and the entire team for this groundbreaking achievement! ??

?? Solutions in Sight: Utilizing computational modeling and Techno-Economic Analysis (TEA) Early use of computational modeling and techno-economical analysis can play a key role in reducing overall costs and improving product quality ?? By developing models, time spent on trial and error at the bench is reduced, bringing down the total costs of reagents used ?? Economic Landscape Here’s a quick recap of the Good Food Institute’s thoughts on the current economic landscape of the alternative proteins sector “Though there’s optimism for some relief in 2024 [1], interest rates remain elevated making it difficult for startups to access free-flowing funding. Investors and stakeholders will expect the capital that companies raise to go further and last longer. Many companies will look to near-term strategies that prioritize cost reductions and quality improvements to reach consumers—even as consumers remain concerned about high costs and personal finances.? For early-stage products and those not yet on the market, identifying intermediate revenue streams in technology licensing and ingredient markets—plus clear progress toward scale-up milestones—will be essential to securing additional funding. To fill the gaps left by the private capital markets [2], it will be increasingly important for governments around the world to continue to support the growing alternative protein sector through investments in R&D, grants, loans, and loan guarantees, and other forms of financing.” — GFI [3] ? What solutions do you think can help overcome these financing challenges in the alternative protein industry? Let’s discuss in the comments below! ? What do you want to learn about computational modeling and doing techno-economic analysis? Let us know in the comments, and we’ll turn it into content! #AlternativeProteins #Biotech #FoodInnovation #Sustainability #Investment #FinancingSustainability [1](https://lnkd.in/gtXHZtAK) [2](https://lnkd.in/gcS7_D-G)? [3](https://lnkd.in/gcS7_D-G)?

?? Exploring the Pain Points of the Alternative Protein (cultivated meat) Industry?? What are some of the available challenges in alternative protein sector ripe for innovation? Here are some key pain points for innovators to tackle: Cell Line Engineering ?? Ammonia build-up in mammalian cell cultures is a significant hurdle.? How can we optimize these processes to ensure healthier cell growth and higher yields? Production Optimization ?? Optimizing both cells and manufacturing processes is critical to reduce costs and save time spent at the bench.? What new strategies for bioprocess optimization can we come up with? Economically Viable Products ?? Economically viable products and processes are essential for market acceptance.? What approaches do you think can help in achieving this goal? Suspension Cultures vs. Adherent Cultures ?? Creating cell cultures that thrive in suspension rather than adherence can significantly reduce costs. ??What applicable research and innovations from #tissueengineering and #biomaterials can be further explored and applied to cultivated meat? Drop your thoughts and questions in the comments, and we’ll create content around what matters most to you!

?? The Challenges of Our Future: Food Insecurity ?? We live on a planet with 8 billion people — and yet 309 million are facing acute hunger. (According to the world's largest humanitarian organization dedicated to solving world hunger) ?? How can we sustainably produce quality food to feed billions daily? We're looking to alternative proteins to solve this global problem ?? Investing in alternative proteins makes a difference by: * Boosting national food security????: Developing local cultivated meat biomanufacturing capabilities reduces reliance on supply chains that are susceptible to disruption caused by war, livestock shortages, and natural disasters.? * Minimizing the environmental impact of traditional farming: Current farming methods contribute to 15% of global greenhouse gas emissions and use 70% of agricultural land—a trend leading to further deforestation, biodiversity loss, and water pollution???? According to the Good Food Institute's report ?? on alternative proteins' role in global food security (Check it out here:https://lnkd.in/gQVwUyxq) Life cycle assessments found cultivated beef requires 95% less land compared to traditional methods. ???? . . ???Follow CMMC and visit our website (https://thecmmc.org/) to see how we’re using computational modeling to accelerate the development of alternative proteins. ?????? ?? Want to learn more about alternative proteins and how the CMMC is driving progress in this field? Follow our page and join our Discord community: https://lnkd.in/gVyDQrBt ?????? Our #careerdevelopment and #volunteering channels are here to help you explore exciting career opportunities in alternative proteins! ?? The Cultivated Meat Modeling Consortium (CMMC) is leading the charge in creating a faster, more affordable future for cultivated meat. Through computational modeling—an innovative and economic solution—we’re tackling key challenges like: ? Reducing the cost of growth media ? Optimizing bioprocess design ? Accelerating scale-up for long-term success

???The Challenges of Our Future: Health Security and Alternative Proteins??? Hello, LinkedIn! It’s been a while since we’ve posted, and we are excited to reconnect with you from?CMMC. As the world faces growing challenges, we are more committed than ever to?accelerating innovation in alternative proteinsand building a?sustainable food system. What’s the Problem? Our climate is shifting—heatwaves, floods, and natural disasters?are becoming more frequent. These changes are creating ideal conditions for?zoonotic diseases—viruses that jump from animals to humans. Recent outbreaks of?SARS, MERS, and Ebola?are stark reminders of the risks. Traditional livestock production systems are particularly vulnerable to?disruptions from disease outbreaks and climate instability, leading to mass culling and worsening?food insecurity. How Can We Address This? ???Alternative Proteins?offer sustainable solutions: ?? Plant-Based Proteins: - Made from soy, peas, lentils, etc. These proteins?require fewer resources?and produce?lower carbon emissions. - They can?mimic the taste and texture of meat, offering consumers a sustainable choice. ?? Fermentation-Based Proteins: - Utilizing?microorganisms?like fungi and yeast, this approach provides nutrient-dense foods with?meat-like textures. - These proteins are?scalable and efficient?to meet global food demands sustainably. ?? Cell-Cultivated Meat and Seafood: - Produced directly from animal cells, cultivated meat replicates the?taste and nutrition of conventional meat without the need for slaughter. - Cultivated meat systems, built in?controlled environments, also minimize the?risk of zoonotic disease transmission. Why Alternative Proteins Matter: ???Health Security:?Lower the risk of disease outbreaks. ???Resilient Supply Chains:?Ensure stable food production, even during climate disruptions. ???Environmental Impact:?Reduce emissions, water use, and deforestation, helping?preserve biodiversity. What’s Next? Weekly Series on Computational Modeling We are excited to share that?every week, we’ll be posting updates?on how?computational modeling?is shaping the future of?cultivated meat production. Through these posts, you’ll learn how modeling is: ???Optimizing bioreactor configurations ???Lowering costs of growth media ???Accelerating innovation and scaling solutions?for the cultivated meat industry Stay Connected and Join the Conversation! 1???Follow our page?for insights on alternative proteins and computational modeling. 2???Join our Discord community?for career and volunteering opportunities:?https://lnkd.in/gVyDQrBt??? 3???Comment below: What are your thoughts on the future of alternative proteins? At?CMMC, we are working to ensure that?health security and food security?go hand-in-hand. Let’s?build a sustainable future together!??? #ClimateChange #AlternativeProteins #CultivatedMeat #HealthSecurity #FoodSecurity

???Innovative Updates from CMMC!??? The Cultivated Meat Modeling Consortium (CMMC) has been at the forefront of the industry for nearly 6 years. We're thrilled to share a blog article by Susan Miller , summarizing key insights from various articles on the impact of computational modeling in cultivated meat science. Discover how our cutting-edge computer tools are accelerating the production of cultivated meat for a sustainable future. Join the conversation! #CMMC #SustainableFood #CultivatedMeat #FoodTech #Innovation

???Looking for Passionate Talent!??? The Cultivated Meat Modeling Consortium (CMMC) is looking for a Part-Time CFD Expert with AI Experience in the Cultivated Meat Industry! ???? Job Title:?Part-Time CFD Expert with AI Experience Location:?Remote Job Type:?Part-Time (10 hours per week) About Us: CMMC is non-profit organization dedicated to advancing lab-grown meat production through innovative research, modeling, and computational tools. We are developing the Bioprocess Evaluation Tool (BET), an online open-source platform using AI and CFD for real-time simulation predictions. Key Responsibilities: - Conduct CFD simulations using OPENFOAM. - Develop AI algorithms to analyze and improve process parameters. - Collaborate with cross-functional teams. - Perform sensitivity analyses and validate simulation results. - Stay updated with the latest advancements in CFD, AI, and cultivated meat technologies. Qualifications: - PhD or Master's in Mechanical Engineering, Chemical Engineering, - Computational Science, or a related field. - Experience with CFD simulations, especially using OPENFOAM. - Strong programming skills (Python, C++, MATLAB). - AI algorithm development experience. - Familiarity with the cultivated meat industry is a plus. - Excellent problem-solving and communication skills. What We Offer: - Competitive hourly rate. - Flexible working hours. - Collaborative and innovative work environment. - Professional development opportunities. How to Apply: Submit your resume, cover letter, and relevant publications or portfolio pieces to?[email protected]. For more details, visit our https://lnkd.in/gjmB9kEj. Join us in revolutionizing the future of food! ???? #Hiring #JobOpportunity #CFD #AI #CultivatedMeat #FoodTech #RemoteWork #Innovation #CMMC