Today marks a major milestone for Strand Therapeutics as we publicly unveil a groundbreaking advancement in mRNA therapy at the 12th International #mRNAHealthConference! Join us in Session 9 at 2:38 PM, where Wen Allen Tseng will present the first-ever demonstration of how our programmable genetic circuits can reduce off-target toxicities, transforming the therapeutic index of mRNA cancer therapeutics.? ? Session Details:? Presentation Time: 2:38 PM? Session: Cancer Vaccines and mRNA Therapeutics I? Title: STX-003: mRNA-Based Cancer Therapy for Tumor-Specific Expression of IL-12 via Programmable Genetic Circuits? ? With STX-003, we’re pushing the boundaries of what’s possible in cancer treatment by making therapies safer and more targeted. Don’t miss this opportunity to witness a transformative leap forward in the field of mRNA-based therapeutics.? ? #CancerTherapy #mRNA #BiotechInnovation #CancerResearch #Immunotherapy #Biotech #TherapeuticIndex #StrandTherapeutics?
Strand Therapeutics
生物技术研究
Boston,Massachusetts 18,322 位关注者
Where synthetic biology meets RNA therapeutics
关于我们
Strand was founded by biological engineers working together at the Massachusetts Institute of Technology (MIT). Building on the idea of creating smart therapies capable of making sophisticated decisions, they sought to apply this concept to the emerging field of mRNA therapeutics. This area was previously untapped by traditional synthetic biology, leading us to build our very own mRNA programming language, creating the world’s first platform for mRNA smart therapies. Strand’s mRNA programming technology promises to make mRNA therapies safer and more effective by programming the location, timing, and intensity of therapeutic protein expression inside a patient’s body via mRNA-encoded logic circuits. These circuits have the ability to implement cell-type specific expressions by sensing and classifying the unique mRNA expression signatures of cells and control the dosage of protein expression through responses to exogenously administered small molecules.
- 网站
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https://www.strandtx.com
Strand Therapeutics的外部链接
- 所属行业
- 生物技术研究
- 规模
- 51-200 人
- 总部
- Boston,Massachusetts
- 类型
- 私人持股
- 创立
- 2017
- 领域
- biotechnology、synthetic biology、RNA therapeutics和Immunotherapy
地点
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主要
21-27 Burlington Ave
US,Massachusetts,Boston,02215
Strand Therapeutics员工
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Shannon Dahl
Visionary Biotechnology Executive, Chief Scientific Officer, Board Advisor || Driving Innovation from Discovery to Go-to-Market || Offering Expertise…
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Colleen Wilson
Senior HR Leader
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Tasuku Kitada
Entrepreneur | Biotech R&D leader | Programming mRNA to cure the world!
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John Edwards
Biotech Executive
动态
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Happy Halloween from all of us at Strand! ?? #Halloween #BiotechNews #Biotech #mRNAResearch #mRNA #mRNATherapies
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Strand had the wonderful opportunity to host some fantastic students from the Princeton Biotech Group during their Boston trip. It was fun to answer questions about mRNA, biotech, being in the clinic, and more! Shoutout to Joseph Lee, Jaspreet Khurana, Joseph Barberio, Aidan Coia, Aidan Simpson, Akshay Mavani, Samta Kundu, and Eva G. for helping out with the tour!
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Being a training facilitator who is also a nursing mom isn’t always glamorous, but a huge shoutout to Strand Therapeutics for having the most comfortable, relaxing wellness room complete with the best decor, coloring books, fun books, and fidget toys. If your wellness room is nothing more than a drab closet, it might be time for an upgrade! It’s a small shift, but it shows your employees how important they and their wellness are!
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New job posting alert! We're #hiring a Vice President of Clinical Development to join our executive team and facilitate clinical strategy for our lead asset. This will be Strand's first full-time MD hire. Interested? Check out the full job description on our job board: https://lnkd.in/ep6KjKCi #newjob #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies
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Last month, some Strands volunteered at The Greater Boston Food Bank. In all, they packed enough groceries to feed a family of four for nearly a year! ?????? #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies
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Shoutout to William P., Aidan Simpson, and Colleen Moran for their poster presentation at the 2024 International Mammalian Synthetic Biology Workshop (mSBW)! They showcased some of Strand's work on synthetic mRNA and genetic circuits. #mSBW2024 #BioTechNews #BioTech #mRNAResearch #mRNA #mRNATherapies AIChE - American Institute of Chemical Engineers
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Today is an exciting day of firsts for Strand Therapeutics.?We are proud to announce the dosing of our first patient with STX-001 in our first Phase 1 trial for the treatment of cancer patients with solid tumors. STX-001 represents the first-ever programmable mRNA therapy to enter clinical trials. STX-001 is an investigational multi-mechanistic, synthetic self-replicating mRNA technology that expresses an IL-12 cytokine for an extended duration, directly into the tumor microenvironment. Join us at ASCO for more information on the trial design: Presentation Date/Time: 6/1/2024 9:00AM-12:00PM CDT Title: A phase I trial of intratumoral STX-001: A novel self-replicating mRNA expressing IL-12 alone or with pembrolizumab in advanced solid tumors. Session: Developmental Therapeutics -- Immunotherapy Location:?McCormick Place, Chicago, Illinois, Hall A Poster Board Number:?161b Permanent Abstract Number:?TPS2696 Read our press release: https://lnkd.in/g-j9vq6v #Programmable #mRNA #Oncology #ClinicalTrials #FirstPatientDosed #ASCO24 #ASCO2024
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Thrilled to share that Ashlesha Odak, PhD will be presenting breakthrough research at #ASGCT2024! Join us on Friday, 5/10/2024, in the Exhibit Hall to explore the potential of circular RNA-based CAR-T cell therapy for combating cancer. Session Details: Presentation Date/Time: 5/10/2024, Noon - 1:30 PM & 5:30 - 7 PM Title: Circular RNA Based Chimeric Antigen Receptor (CAR) Cell Therapy for Potent and Long-lasting Anti-Tumor Activity Session: Friday Posters: In Vivo Therapy Approaches Presentation Room: Exhibit Hall Abstract #: 1825 This groundbreaking in-body engineering approach promises to revolutionize the landscape of cell therapy, eliminating the traditional complexities associated with ex vivo therapies. By significantly slashing treatment costs and expanding access, this innovative method is set to transform medical care, bringing crucial therapies within reach of more patients. Don’t miss out on how we are advancing the frontiers of cancer treatment with our latest research. #ASGCT24 #CARTherapy #CancerTherapy #InVivoTherapy #BiotechInnovation #Biotech
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Excited to announce that Wen Allen Tseng will be presenting our groundbreaking research at #ASGCT2024! Join us on 5/9/2024 in the Exhibit Hall for an in-depth look at STX-003, our latest innovation in programmable mRNA cancer therapy. Session Details: Presentation Date/Time: 5/9/2024, Noon - 1:30 PM & 5:30 - 7 PM Title:?STX-003: A Novel Systemically-Delivered mRNA-Based Cancer Therapy Utilizing a Programmable Genetic Circuit Platform for Tumor-Specific Protein Expression and Reduced Toxicity Session: Thursday Posters: Cancer - Immunotherapy and Cancer Vaccines Presentation Room: Exhibit Hall Abstract #: 1272 STX-003 is designed to revolutionize cancer treatment through a programmable genetic circuit platform, enabling tumor-specific protein expression with significantly reduced toxicity. Don’t miss out on how we’re pushing the boundaries of science to fight cancer more effectively. #ASGCT24 #mRNA #CancerTherapy #Immunotherapy #CancerVaccine #BiotechInnovation #Biotech