Today marks the inaugural Autosomal Dominant Optic Atrophy (#ADOA) Awareness Day. We applaud the patient advocacy community for coming together to recognize the lived experiences of families and individuals with ADOA, a rare condition that causes low vision, and even sometimes complete vision loss. Thank you to the Autosomal Dominant Optic Atrophy Association (ADOAA) and Cure ADOA Foundation for your continued advocacy. #ADOAawarenessDAY
关于我们
Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to addressing the underlying cause of severe diseases. The company is pursuing an entirely new approach to treating severe diseases. We are initially focused on diseases of the central nervous system and the eye, with an emphasis on haploinsufficiencies, which are diseases caused by a loss of about half of the normal protein function. Rather than replace, repair or edit faulty genes, we aim to increase – or stoke – protein output from healthy genes to restore functional protein levels using our proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) platform. In all, Stoke has identified ~6500 genes with a TANGO signature, representing broad potential for our approach to help people with severe diseases. The early results have been promising. Stoke’s first medicine in development, STK-001 has demonstrated positive Phase 1/2 results for the treatment of Dravet syndrome, a severe and progressive genetic epilepsy that is associated with a number of debilitating non-seizure comorbidities. Behind that, is STK-002, a potential treatment for autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. Clinical studies of STK-002 are anticipated to start in 2024. The company is pursuing potential treatments for three additional neurodevelopmental disorders, including Syngap1 and Rett syndrome, in collaboration with Acadia Pharmaceuticals. Stoke is headquartered in Bedford, Massachusetts with offices in Cambridge, Massachusetts.
- 网站
-
https://www.stoketherapeutics.com/
Stoke Therapeutics的外部链接
- 所属行业
- 生物技术研究
- 规模
- 51-200 人
- 总部
- Bedford，Massachusetts
- 类型
- 上市公司
- 创立
- 2017
地点
-
主要
获取路线
45 Wiggins Ave
US，Massachusetts，Bedford，01730
Stoke Therapeutics员工
动态
-
Stoke Therapeutics management will present at the Jefferies London Healthcare Conference today, Wednesday, November 20, at 6:30am EST (11:30am GMT). A live webcast of the presentation by our CEO, Edward M. Kaye, MD will be available on the Investors & News section of our website: https://lnkd.in/eHhCGGQs #JefferiesHealthcare?
-
-
It’s Epilepsy Awareness Day at Disneyland! Stoke is proud to attend this year’s event joining advocates, families, and clinicians. We’re grateful for the organizers for all their efforts in raising awareness, dispelling misconceptions and sharing knowledge.? ?? #ThePurplestPlaceOnEarth?#EpilepsyAwarenessDayAtDisneyland
-
-
Living with #DravetSyndrome takes resilience. Not only from patients, but also from the caregivers who provide support, love, and care each day.?? ? This #FamilyCaregiversMonth, Stoke Therapeutics honors the strength of caregivers, recognizing their role in each patient's journey.?? ? For caregiver tools, resources and support, visit the Dravet Syndrome Foundation: https://lnkd.in/eJbG3VpD
-
-
Celebrating #Diwali is a beloved tradition at Stoke. As the Festival of Lights, our team looks forward to celebrating together every year with lights, food, and a sense of community. This meaningful holiday symbolizes renewal, unity, and togetherness – all values that resonate deeply within our team. #StokedAboutStoke
-
-
We’re proud to support Biomedical Science Careers Program (BSCP)’s Evening of Hope, an event dedicated to advancing opportunities for underrepresented minorities and inspiring future leaders in biomedical sciences.?? ? The work of BSCP in fostering diversity and inclusion is critical in shaping the future of healthcare. We’re honored to support their important mission.? ? Together, we can continue to break down barriers and create pathways for the next generation of experts in science and medicine.? ? #BSCP?#eveningofhope2024
To say that our paddle raise portion of the event was a rousing success would be an understatement!! Thank you so much to the BSCP community!! #fundthemission #bscp #eveningofhope
-
Today on #SUDEPActionDay2024, we’re raising awareness about Sudden Unexpected Death in Epilepsy (SUDEP) and the importance of understanding this serious risk.??? ? Raising awareness about the risks associated with epilepsy is essential. Taking an active role in discussing, reviewing, and reducing these risks helps ensure that those affected by epilepsy can live safer and healthier lives.? ? We stand with the epilepsy community and support families navigating these challenges.? ? Learn more and get involved:??https://lnkd.in/em8nkZy? ?? #SUDEP #OurRisksOurRights
Today is #SUDEPActionDay2024 & we are uniting with organisations around the world to raise awareness of the rights of people with epilepsy or those bereaved by it. The epilepsy community is entitled to have their questions answered and have the right to information, medication and care. Share our posts and tag us @sudepaction
-
-
I'm elated to share that our manuscript titled “Antisense Oligonucleotide STK-002 Increases OPA1 in Retina and Improves Mitochondrial Function in Autosomal Dominant Optic Atrophy Cells” was recently accepted for publication in Nucleic Acid Therapeutics and is now available online! https://lnkd.in/etXWiw4t This study presents preclinical data?that support the progression of STK-002 towards the clinic as the first potential disease-modifying treatment for autosomal dominant optic atrophy (ADOA), an inherited disease that often leads to blindness and currently has no treatment. A heartfelt thank you to my amazing colleagues and mentors at Stoke Therapeutics who contributed their time,?expertise, and passion to this project. Your dedication and collaboration were invaluable and made this accomplishment possible. Reflecting on this journey, I’m reminded of how fulfilling and satisfying it is?to engage in research that not only pushes the boundaries of knowledge but also holds the potential to make a difference in the lives of patients suffering from severe genetic diseases. It’s a powerful reminder of why we do what we do at Stoke! #oligonucleotide #antisense #RNA #ADOA #OPA1 #biotech
-
Today, Stoke announced highlights from presentations at the?15th?European Epilepsy Congress?related to the Company’s work to develop the first disease-modifying medicine for #Dravetsyndrome. Learn more in our press release: https://lnkd.in/dxKt8Pbm #ILAE?#EEC2024?International League Against Epilepsy
-
-
Stoke is pleased to announce the appointment of Eric Olson as Chief Business Officer. Mr. Olson brings two decades of successful corporate business development experience with an emphasis on #rarediseases and #RNA therapeutics https://lnkd.in/eT4Nk7bv