Standard BioTools

Standard BioTools today announced the addition of KREX? precision antibody profiling services and kits to its SomaScan? suite of solutions.?The expanded offering enables the detection of autoantibody biomarkers and protein interactions for basic, translational and clinical research. "Our enhanced SomaScan platform, powered in part by the complementary KREX? technology, represents another step forward in our ability to address the needs of biopharma and translational research," said Michael Egholm, PhD, President and Chief Executive Officer of Standard BioTools. "Fitting squarely within our 'omics as a service offering, we're excited to offer customers expanded SomaScan functionality, enabling deeper insights and more impactful discoveries." Read more: https://lnkd.in/gj9bGd87

Why is glioblastoma so resistant to treatment? Hear H. Artee L., PhD, present new findings revealing mechanisms that influence immunosuppression by reducing T cell recruitment. Using a cancer stem cell mouse model of glioblastoma and a multi-omic approach that includes Hyperion? imaging, the study addresses the need to explore the role of the microenvironment in resistance to therapy with tailored pre-clinical models. ? Learn more about the work conducted by Kyle Heemskerk, PhD candidate in the Luchman Lab, at the 29th Annual Meeting and Education Day of the Society for Neuro-Oncology, on November 22 at 11:35 am: Multi-omic characterization of a syngeneic mouse cancer stem cell model of GBM for preclinical applications ? See the agenda for #SNO2024: https://lnkd.in/g73RWEH2

Our high-content platforms for serum, spatial, and single-cell -omics deliver unparalleled content, precision, and scalability, setting a new standard in the life sciences industry.?Learn about multi-omic applications involving high-plex proteomics and how AI can help guide region selection for imaging projects with Tala Khosroheidari?and?James R. Mansfield at?Multi Omics 2024 next week in Brisbane, Australia.

Immunotherapy has significantly improved the prognosis for patients with esophageal cancer, a rare but deadly form of the disease. In this new paper published in Nature Magazine, researchers from Kyushu University used Hyperion? imaging and CyTOF??systems to provide new insights into the mechanisms of therapeutic response, including both local to the tumor and systemic response after treatment. ? This study identified specific cell populations that are crucial in the success of immune checkpoint blockade therapy for esophageal squamous cell cancer and key to anti-tumor response, which may pave the way for more effective treatments.? ? Read more about this research here: https://lnkd.in/eryFjuBJ Learn more about our #immunooncology solutions here: https://lnkd.in/eyczK7gh #cancer #immunotherapy #imaging #CyTOF

Check out this new #OMIP that outlines the development of a 42-parameter #masscytometry panel for broad immunophenotyping of leukocytes from bronchoalveolar lavage from rhesus macaques. The panel supports studies into the correlates of vaccine-induced protection against #tuberculosis and is the first cytometric panel of its kind for rhesus macaques. CyTOF? technology was chosen for this purpose because the autofluorescence inherent to alveolar macrophages interferes with characterization of myeloid cell populations by fluorescence flow cytometry. The metal tags used in CyTOF panels eliminate the challenges with autofluorescence in tissues. Using this panel on cryopreserved samples, the team identified myeloid populations such as macrophages, neutrophils, monocytes, myeloid and plasmacytoid DCs, basophils and lymphoid cell lineages including B cells, NK cells, multiple T cell populations and innate lymphoid cells, as well as markers for defining memory, differentiation, homing potential, cytotoxic potential, cell activation/differentiation and effector function. Makatsa et al. 2024: https://lnkd.in/gYRujeaC

A big thank you to everyone who stopped by our booth at #SITC2024! We loved connecting with so many passionate cancer researchers and clinicians, and we’re grateful for the inspiring conversations and insights shared.? ? This year was especially exciting as we unveiled our new corporate and product branding for the very first time. We’re thrilled to share this fresh chapter in our journey with you all! In case you missed it in person, watch our wrap-up video.? #LifeScienceResearch #Proteomics #Genomics #ImmunoOncology??

Michael Egholm, PhD, President and CEO of Standard BioTools, will participate in the Jefferies London Healthcare Conference with a corporate presentation on Tuesday, November 19, at 8:30am GMT. This year’s gathering marks the 15th anniversary of the largest healthcare-dedicated conference in Europe and brings together leading executives to address near-and long-term investment opportunities as well as the current trends driving healthcare across the globe. Egholm will introduce a new standard of omics that scale with precision, discussing how higher levels of content and unique scalability of a suite of high-plex proteomics and genomics tools can reveal predictive impact in clinical and translational research. #JefferiesHealthcare

We're constantly innovating solutions to accelerate cancer research and are thrilled to share highlights at the 2nd Spatial Biology Congress Asia in Singapore! Join Jackwee Lim, PhD, Head of #CyTOF at the Singapore Immunology Network, as he discusses how examining the complete spatial distribution of sialylation across the entire tissue helps capture all areas of interest without missing any details. This approach accelerates biomarker discovery, addressing unmet needs in cancer research. (Also,?stop by our booth to learn how you can?get a chance to win an iPad Air!??)? More about spatial biology:?https://lnkd.in/gUSjKBSs

The 17th European Public Health Conference is this week in Lisbon! We are thrilled to be sharing the unique ability of the Biomark? X9 System to simultaneously profile multiple types of genomic assay readouts in a single run. This can be done with minimal technician time and a decrease in sample volumes by 1000-fold over conventional systems, enabling rapid response to potential outbreaks and advancing public health initiatives. Stop by Booth 7 to talk with Amélie Barthelemy, Beate Schurek and Roberto Spada. Learn more about these innovations aimed at improving #publichealth: https://lnkd.in/grg3fGVW

Will you be in Utrecht on November 14? Join us! The 2nd?Annual UMC Utrecht Spatial Omics Symposium, hosted by the UMCU Spatial Omics Accelerator, will highlight some of the most advanced imaging technologies to date and present ways to navigate the challenges and opportunities in spatial biology. This includes identifying the spatial immune architecture associated with disease, spatial omics for biomarker discovery, computational spatial biology and integrative analysis of multiple datasets. We’d like to share that Hester Koppejan, PhD, will be giving a talk at 11:40am titled, Unlocking a New View in Spatial Biology with the Hyperion? XTi Imaging System See who’s talking, and get a seat: https://lnkd.in/g9TMCb_b