SomaLogic

What’s a good coefficient of variation? While proximity ligation assays range from 5-20% and mass spectrometry runs from 10-20%, we like to see a CV of ~5%. Why? Because median CVs of ~5% provide an unmatched level of precision that allows you to reliably perform analysis and clinical studies with fewer participants. Get this – relative to the SomaScan Assay ~5% CV, other platforms with 10% CV would need about 2,300 more samples to detect a 1% difference in means. Use our interactive sample calculator to see how many additional samples you might need to account for technical variation when using different platforms with varying levels of coefficients of variation: https://lnkd.in/dMAJKgmq

Applications for the?SomaScan? Australia Research Grant Award close on 31 October! Did you know:?the?SomaScan? 11K Assay is now available for CSF, cell lysates and tissue homogenates? This?gives researchers access to half of the human proteome in just one assay. Our?SomaScan assay can be used for a wide range of applications, such as biomarker discovery, cancer research, and multi-omic research.?Apply now: https://lnkd.in/ghS5U--N

Just 1 week left to register for the 2024 Proteomics Day in Dresden, Germany! Get ready for an exciting deep dive into?Next-Generation Proteomics: Transforming Precision Medicine. Whether you're a researcher, clinician, or industry expert, this event is the perfect opportunity to explore the latest advancements in proteomics! ???Date:?Saturday, 19 October 2024 ???Time:?9:00 AM - 6:00 PM CEST ???Location:?International Congress Center Dresden, Germany ???Registration is free and compulsory—don't miss out on this chance to connect and learn with leaders in the field! Register now and secure your spot!?https://lnkd.in/g4Pg68-B Speakers: Stephen Williams, MD, PhD, Standard BioTools Karl Smith Byrne, PhD, Oxford University Jessica Makofske, PhD, Novartis Nebojsa Janjic, PhD, Standard BioTools Fridtjof Lund-Johansen, PhD, Oslo University Hospital Sarah Brüningk, PhD, ETH Zurich David Astling, PhD, Standard BioTools Amanda Sj?gren, PhD, Lund University #ProteomicsDay #PrecisionMedicine #SomaLogic #StandardBioTools #Proteomics #Dresden #FreeEvent #ScienceInnovation #HUPO2024

??30 October, 10am SGT???Join Helen McGuire PhD, Senior Lecturer at the University of Sydney, as she shares a cutting-edge approach to immune monitoring in multi-site clinical trials—simplifying sample collection and benefiting remote and underrepresented populations. ?? Discover a novel immune signature that predicts non-responsiveness to checkpoint therapies, offering a powerful tool for treatment decisions.? ?? Explore how the SomaScan? Platform, with 11,000 protein measurements, tracks disease progression and immune response in real time.? ?? Learn how combining cellular and plasma data can improve clinical outcome prediction, incorporating?multi-omic data integration into your research. Registration is free:?https://lnkd.in/gEvvZXmM

??Congratulations to the new Nobel Prize winners in Chemistry, David Baker, Demis Hassabis and John M. Jumper, for their research in protein structures! We're excited that proteins are now taking center stage in research with these important projects. For more than 20 years we've put our efforts into studying proteins and the potential they have for helping us understand our own biology. We look forward to seeing, and participating in, what the future of protein research brings! https://lnkd.in/eknNuN4C

Will you be in Denver for #ASHG next month? Join us Monday, November 4th for the Pre-ASHG Proteomics/Multi-Omics Symposium.?? ? Discover the power of proteomics in the multi-omics arena using the SomaScan? Assay, which enables measurement of 11,000 proteins—covering half of the human proteome!?? ? ?? What to Expect:? - Outstanding presentations by thought leaders from Cleveland Clinic, Edgewise Therapeutics, Precision Health Research at Singapore, NIAID, USC, Alkahest, Johnson & Johnson Innovative Medicine and Washington University - Morning pastries, lunch, afternoon snacks and a networking reception with beer, wine and light snacks? ? Don’t miss this chance to connect and collaborate with fellow researchers before the ASHG conference! During the conference you can find us at ASHG booth 145.? ? ?? FREE registration! https://lnkd.in/gnC7-BKb ? ?? Location:??? Embassy Suites, Cripple Creek 1 Meeting Room??? 1420 Stout Street, Denver, CO 80202? ? Speakers:? o Ben Barthel, PhD - Principal Scientist at Edgewise Therapeutics o Russell Bowler, MD, PhD - Chair Genomic Sciences and System Biology. Cleveland Clinic oJohn Chambers, PhD - Professor, Cardiovascular Epidemiology (President’s Chair) at Nanyang Technological University Singapore. Chief Scientific Officer of PRECISE (Precision Health Research, Singapore)? oJames Cherry, PhD - Associate Director, Research Technologies, DIR, National Institute of Allergy and Infectious Diseases (NIAID). Chief, Research Technology Branch & Center for Human Immunology? oJuliet Emamaullee M.D., Ph.D. Juliet Emamaullee, MD, PhD? Associate Professor and Associate Chief of Surgery and Immunology Department, Keck School of Medicine of the University of Southern California o Benoit Lehallier Benoit Lehallier, PhD - Senior Director Of Data Science. Alkahest, Inc. (a Grifols Company)? o Dan Western, MS (on behalf of Carlos Cruchaga, PhD – Professor of Psychiatry) - Human and Statistical Genetics at Washington University in St. Louis Washington University? o Chris Whelan Chris Whelan, PhD - Director at Johnson & Johnson Innovative Medicine, Founder & Chair, Pharma Proteomics Project

Expanding the SomaScan? Platform to include more sample types, including CSF, cell lysates and tissue homogenates opens new avenues for biomarker discovery. The use of high-throughput proteomics in cerebrospinal fluid for neurodegenerative disease research is key to providing information on biological changes occurring in the brain. The SomaScan Platform’s sensitivity to these changes is expected to give researchers a wealth of neurological data. Learn more about how we’re setting a new standard for discovery: https://lnkd.in/gGcTYkpm

Attending #HUPO2024 ??Join us Tuesday morning (8:00-9:00am) for a light breakfast and an in-depth look with Fridtjof Lund-Johansen?into the innovative methodologies used to evaluate the specificity of affinity reagents in the SomaScan? Assay. ?? Visit us at Booth 22 from 20-24 October to meet our scientific team! Learn more about our activities at HUPO here?:?https://lnkd.in/dvAc-_-3

What does a coefficient of variation of ~5% mean? That you can use the fewest number of samples to detect the smallest biological changes. Without this level of precision, many of these changes cannot be reliably tested in individuals, and clinical studies end up requiring many more participants. Take a look at this white paper explaining why coefficient of variation is a critical metric: https://lnkd.in/dmjihbfm

We’re setting a new standard: The most protein measurements on the most sample types. SomaScan? 11K Assay is now available for CSF, cell lysates and tissue homogenates. The SomaScan Assay offers the broadest coverage of the proteome—11,000 protein measurements simultaneously from samples as small as 55μl—giving researchers access to half of the human proteome in just one assay. And, these new matrices are now available from Standard BioTools’ Discovery Labs in Boulder, Colorado and from SomaScan? Authorized Sites around the world. Learn more here: https://lnkd.in/gGcTYkpm