SigTuple

??Anemia: A Silent Epidemic Among Women – The Need for Early Screening Anemia affects millions of women worldwide, yet it often goes unnoticed until it leads to serious health complications. Early screening is not just important—it is critical in preventing long-term health risks. Join us in the next session of our Webinar Series, where we delve into this urgent topic with an expert in the field: Dr. Manjula SJ Head of the Department – Haematology & Senior Consultant Pathologist Apollo Hospitals, Bannerghatta Road, Bengaluru Dr. Manjula brings extensive experience in Hemato-oncology, Bone Marrow Biopsies, Flow Cytometry, and Lab Management. She will share her insights on why early detection of anemia in women is a game-changer in clinical practice. ?? Date: March 1, 2025 ?? Time: 6:00 PM to 7:00 PM ?? Registration Link: https://lnkd.in/gE7GS9TK Don't let anemia remain undiagnosed. Be part of the conversation that can save lives. Register now! #AnemiaAwareness #EarlyScreening #WomensHealth Dr. Renu Ethirajan Suman Gautam Pranat Bhadani Tathagato Rai Dastidar Dr. Sharitha Naganna Dr. Pavithra Devi Dr. Chaitra C Dr. Gayatri

?? SigTuple at MP PathCon 2025 – Bringing AI to Pathology! ?? Our team had the privilege of participating in MP PathCon 2025, held at Government Medical College, Datia, on February 22nd & 23rd. This annual conference serves as a platform for leading pathologists from Madhya Pradesh and neighboring states to explore the latest advancements in pathology. At the event, we proudly showcased SigTuple’s AI-powered digital microscopy, demonstrating its capabilities to a highly engaged audience. The response was truly overwhelming – pathologists were eager to experience how our technology can modernize their workflow and enhance diagnostic accuracy. A big thank you to all the visitors who stopped by to explore the future of pathology with us! #MPPathCon2025 #AIinHealthcare #SigTuple #FutureOfDiagnostics Purab Shrivastava Intezar Ali Suman Gautam Pranat Bhadani Tathagato Rai Dastidar Dr. Renu Ethirajan

?? AI100 Unveils Lymphoma Spillover on Peripheral Blood Smear ?? Continuing our series on interesting hematology cases, we bring you a case where AI100 played a crucial role in early detection and diagnosis of lymphoma spillover. Case Details: A 48-year-old male with an unresolved low-grade fever for 6 months. No significant weight loss. ANA immunoblot was negative, but ANA by IFA was positive. CBC Findings: * Hemoglobin: 9.7 g/dl * WBC Count: 14.14 x 103/cumm * Platelets: 1,16,000/cumm * Differential Count: Monocytosis (22.9%) Analyser Flags Raised: * Blasts? * Abnormal lymphocytes? * Immature granulocytes? * Atypical lymphocytes? * Left Shift? * Monocytosis AI100’s Role in Diagnosis: When the peripheral blood smear was scanned on AI100, it flagged 13.2% monocytes and detected large atypical cells with convoluted nuclei, scanty to moderate cytoplasm, and conspicuous nucleoli. Although the percentage of such cells was low, the visual evidence and automated flagging provided by AI100 helped the pathologist identify suspicious cells early and recommend a bone marrow aspiration. Final Diagnosis: Lymphomatous involvement was confirmed on bone marrow aspiration. Key Takeaways: * Early detection is crucial – AI100’s screening provided a critical first step in identifying abnormal lymphoid cells. * Peripheral smear screening is essential – Especially in cases of pyrexia of unknown origin (PUO). * Non-Hodgkin Lymphomas (NHL) when present with atypical lymphoid cells spilling into the peripheral blood, AI100 helps in their timely detection. * A proper correlation of clinical findings, CBC, and PBS can significantly impact early diagnosis and prognosis. Why AI100? Pathologists face increasing workloads, making AI-driven tools like AI100 indispensable. AI100 aids in efficiently screening for hematological malignancies, identifying rare cells, and providing visual evidence to support timely decision-making. Empower your hematology lab with AI100 – a reliable partner in the fight against blood disorders. Case Courtesy: Dr. Saumil Sanghavi, Sanghavi Diagnostics, Mumbai. #AIinHealthcare #Lymphoma #SigTuple Dr. Renu Ethirajan Suman Gautam Pranat Bhadani Tathagato Rai Dastidar Dr Gayatri Dr Sharitha Naganna Dr Chaitra C Dr Pavithra Devi

"This case reaffirmed our belief that AI-powered hematology is a game-changer. At Udyati, we now have a powerful ally in the fight against blood cancers. Human life is invaluable, and early detection is our best weapon" - we couldn't have said this any better!

Interesting Case Series: AI100 in Anemia Diagnosis and Management Anemia is one of the most common and complex clinical conditions, requiring a systematic and careful approach to diagnosis and management. At SigTuple, we’re proud to see how our AI100 device has been assisting pathologists in simplifying these challenges and delivering precise insights into anemia cases. In this edition of our Interesting Case Series, we explore: * How AI100 aids in morphological analysis of RBCs, WBCs, and platelets. * Real-world cases where AI100 flagged critical findings, including microcytic hypochromic anemia, early hemolysis, and acute leukemia. From flagging fragmented RBCs to detecting nRBCs and blasts, AI100 empowers pathologists with accuracy and efficiency, enabling quicker decision-making and better patient outcomes. ?? Dive into the details of these fascinating cases by checking out the attachment. ?? Special thanks to Dr. Arivarsan, Neuberg Bose Clinic, Madurai, for sharing these insights. We invite pathologists to embrace the AI100 device to ease the burden of anemia diagnosis, streamline their workflow, and focus on what truly matters—providing exceptional care to patients. Together, let’s harness the power of AI to transform diagnostics. #AIinHealthcare #AI100 #Pathology #SigTuple Dr. Renu Ethirajan Dr Sharitha Naganna Dr Chaitra C Dr Pavithra Devi Suman Gautam Pranat Bhadani Tathagato Rai Dastidar

Revolutionizing Leukemia Screening with AI100 Accurate and timely diagnosis of acute leukemia can be lifesaving, but the process requires a seamless blend of clinical insight, morphological evaluation, and advanced testing. In a recent case of a 74-year-old patient presenting with severe anemia, AI100 emerged as a game-changer in early screening. The Challenge: Blasts in peripheral blood smears often go undetected or unflagged accurately by traditional hematology analyzers, necessitating time-consuming and manual microscopic examination. The AI100 Solution: When the peripheral blood smear was screened using SigTuple AI100, it: ? Detected 51% blasts with high precision. ? Provided visual evidence of blasts with fine chromatin and conspicuous nucleoli. ? Enabled the pathologist to promptly recommend confirmatory tests. ? Accelerated the diagnostic process, empowering the clinician to make timely decisions for patient management. Why AI100? AI100 transforms traditional microscopy into a cloud-enabled, AI-powered digital microscopy that brings speed, accuracy, and convenience to the diagnostic process: ?? Standardization & Reproducibility: Overcomes manual fatigue and bias. ?? Remote Reporting: Pathologists can access digital smears anywhere, anytime. ?? Confidence in Diagnosis: Visual evidence complements the pathologist’s expertise. At SigTuple, we believe that artificial intelligence enhances the capabilities of medical professionals. With tools like AI100, pathologists can focus on what truly matters: providing the best possible care to patients. ?? It’s time to rethink pathology! Start adopting AI-driven tools like AI100 to revolutionize your workflow and deliver faster, more accurate diagnoses. Together, let’s shape the future of diagnostics! ?? A big thank you to Dr. saumil sanghavi of Sanghavi Diagnostics, Mumbai, for sharing this impactful case. #SigTuple #LeukemiaScreening #innovationinhealthcare Dr. Renu Ethirajan Dr. Gayathri Dr. Sharitha Naganna Dr. Pavithra Devi Dr. Chaitra C Suman Gautam Pranat Bhadani Tathagato Rai Dastidar

Proud moments at the Deeptech Innovation Conclave, organized by Global Forum for Sustainable Transformation (GFST) and the Government of Andhra Pradesh! Over two incredible days, SigTuple had the honor of showcasing our revolutionary AI100 product at this prestigious event in Visakhapatnam We were deeply privileged to host: Honorable Chief Minister of Andhra Pradesh, Shri Nara Chandrababu Naidu gaaru Honorable Minister of Health, Family Welfare and Medical Education in Government of Andhra Pradesh, Shri Satya Kumar Yadav gaaru This visit to our booth was an acknowledgment of the impact AI-powered healthcare solutions like AI100 can have on transforming diagnostics. It was a proud moment for our team, led by: Dr. Tathagato Rai Dastidar (Founder and CEO at SigTuple) Mr. Pranat Bhadani (Cofounder and President - Business growth at SigTuple) Dr. Ramesh Byrapaneni (Managing Director at Endiya Partners) Such recognition inspires us to continue driving innovation and making quality diagnostics accessible to all. A big thank you to everyone who made this event a grand success! #Healthcare #AI100 #DeepTech #SigTuple

?? Join Our Exclusive Webinar Series on Digital Pathology! ?? Episode 7: Digital Pathology: From Crafting to Adopting – A Pathologist's Perspective ?? Date: November 30, 2024 ?? Time: 6:00 PM to 7:00 PM ?? Guest Speaker: Dr. Richa Sharma Senior Consultant, Department of Lab Medicine, Max Super Specialty Hospital, Dwarka, Delhi Discover the fascinating journey of digital pathology from innovation to implementation! In this episode, Dr. Richa Sharma will share her unique perspective as both a creator and user of cutting-edge technology in pathology. Dr. Richa was part of the team that developed this transformative technology during her tenure at SigTuple Technologies. Today, she uses it in her clinical practice, bridging the gap between innovation and real-world applications. With a strong foundation in Histopathology, Hematopathology, and Neuropathology, Dr. Sharma has an illustrious career that includes roles in startups, private setups, and leading healthcare institutions. She pursued her post-graduation at Bangalore Medical College and Research Institute and a fellowship in Neuropathology at Seth GSMC and King Edward Memorial Hospital, Mumbai ?? Registration Link: https://lnkd.in/g7gcNMd9 ?? Don’t miss this chance to hear from an innovator and practitioner at the forefront of digital pathology. Reserve your spot today and be part of this insightful discussion! Spread the word and tag a colleague or friend who might be interested! ?? #DigitalPathology #AIInHealthcare #Webinar Note: Registered participants will receive a confirmation email with access details for this secure webinar platform. Dr. Renu Ethirajan Dr. Sharitha Naganna Dr. Pavithra Devi Dr. Chaitra C Dr. Gayathri Talapula Suman Gautam Pranat Bhadani

An Interesting case of AIHA We continue our exploration of impactful case studies diagnosed with SigTuple's AI100, demonstrating how cutting-edge technology transforms clinical diagnostics. Case Overview: A 9-year-old female presented with lymphadenopathy and icterus, with laboratory findings suggesting Autoimmune Hemolytic Anemia (AIHA). Hb: 6.7 g/dl MCV: 137 fL Flags: Macrocytosis, Anisocytosis, and Anemia SigTuple's AI100 powered by SHONIT flagged macrocytosis and revealed RBC agglutination in its microscopic view. These critical observations guided the pathologist to conduct a Coombs test, which confirmed the diagnosis of AIHA. The Bigger Picture: AIHA is a rare disorder characterized by immune-mediated RBC destruction, impacting only 13 per 100,000 individuals annually. Diagnosis demands a detailed correlation of clinical findings, lab markers, and advanced diagnostics. With AI100’s precise flagging capabilities and high-resolution imaging, pathologists gain clarity in identifying hallmark features like macrocytosis and RBC agglutination, enabling quicker, informed decisions. This case exemplifies how the integration of AI-driven tools in routine pathology amplifies diagnostic confidence, especially in challenging cases. We’re proud of how AI100 continues to empower clinicians to deliver accurate and timely diagnoses. Case Courtesy: Dr Arivarasan, Bose Clinic Lab, Madurai The full case study is attached for your reference #AIinHealthcare #SigTuple #Earlydiagnosis Dr. Renu Ethirajan Suman Gautam Pranat Bhadani Tathagato Rai Dastidar Dr. Chaitra C Dr. Sharitha Naganna Dr. Pavithra Devi Dr. Gayatri

? Day 3 at Hematocon-2024: A Milestone Moment for SigTuple! ? Today, we proudly unveiled our groundbreaking device, AS76, in the presence of some of the most respected stalwarts in the industry. We’re beyond thrilled to have introduced this innovation in digital microscopy with the support of such esteemed leaders and visionaries. Over the past three days, it’s been an honor to showcase AS76 to some of the most distinguished professionals in the field. Their engagement and insights are a testament to the impact this technology promises to bring to digital diagnostics. ?? We’re still open at Stall G5! ?? Don’t miss your chance to visit us and get a firsthand experience of the future of microscopy. Our team is here to walk you through the incredible features of AS76 and discuss how this technology is set to transform diagnostics. A heartfelt thank you to everyone who has joined us so far. Together, we’re paving the way for a new era in healthcare! ?? Stall G5 | Haematocon Nagpur-2024 #SigTuple #AS76Unveiling #Haematocon2024 Tathagato Rai Dastidar Pranat Bhadani Dr. Renu Ethirajan Suman Gautam Dr Pratik Doshi Dr Gayathri Dr Pavithra Devi