Sanford Burnham Prebys

Join us in accelerating the research that brings real-world treatments to life and helps us achieve our common goal:?enhanced health and?greater well-being for all. Support Sanford Burnham Prebys today by visiting:?https://lnkd.in/ent4PNQu.

?? Even with huge growth in the global #antibody market, there’s still untapped potential—especially when it comes to tricky targets like #proteincomplexes. Scientists at Sanford Burnham Prebys and Eli Lilly and Company found a way to make antibody generation more effective by fusing protein complexes together. This stabilizes them during immunization and opens the door to studying more disease-related proteins. ?? Published March 5, 2025, in ????? ?????????????? ???? ????????????????????, this work could help lead to new research breakthroughs—and maybe even new treatments. #immunology #biotech #research #proteincomplexes #lifesciences Read more: https://vist.ly/3myac4w

????? Introducing ????? ?????????????????? ?????????????????? ??????????????, a new series by Ani Deshpande, PhD, and Pamela Itkin-Ansari, PhD, where they explore the history of groundbreaking discoveries in life, science and medicine. Listen to the inaugural episode, ?????????????? ????? ?????????????? ???? ????????????????, which examines the early descriptions of diabetes across ancient civilizations and traces key scientific breakthroughs, including the identification of the pancreas, the discovery of insulin and its transformative impact on diabetes treatment. Available now on multiple streaming platforms: ?? Amazon Music: https://vist.ly/3my7z79 ?? Apple Podcasts: https://vist.ly/3my7z7a ?? Spotify: https://bit.ly/3DDVjsM ?? YouTube: https://vist.ly/3my7z7b

Join us for ?? ???????????????????????? ??????????: ?????????? ?????? ??????????????????’?? ??????????????! Hear from neuroscientists at Sanford Burnham Prebys as they discuss the latest breakthroughs in understanding Alzheimer’s disease. Learn how fundamental science is driving progress toward better treatments and interventions. After the panel discussion, ???????????? ?????????????? author?Muffy WALKER will?share insights from her new novel which explores the impact of Alzheimer’s on families and caregivers. A book signing will follow. ?Learn more and register: ?? ?? ?? https://bit.ly/4i9ejhx #alzheimersawareness #research #aging #alzheimersresearch #sandiego #lajolla?

David Brenner, president and CEO of Sanford Burnham Prebys, has just published a new letter discussing how recent policy changes by the National Institutes of Health (NIH) are threatening essential research, innovation and the future of life-saving medical breakthroughs. Be sure to read it now. #NIH #indirectcosts #research #medicalresearch #biomedicalresearch

In humans and other multicellular organisms, cells multiply. This defining feature allows embryos to grow into adulthood, and enables the healing of the many bumps, bruises and scrapes along the way. Certain factors can cause cells to abandon this characteristic and enter a zombie-like state known as #senescence where they persist but no longer divide to make new cells. Senescent cells also are prone to secreting inflammatory molecules that can contribute to chronic inflammation in the body. This inflammation brings greater risk for age-related diseases. Scientists at Sanford Burnham Prebys and collaborators across the country published findings March 5, 2025, in Nature Communications showing that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the secretion of inflammatory molecules by senescent cells. With additional research, it may be possible to design a treatment based on these findings to promote healthier aging. Read more: https://vist.ly/3mxd3z2

A recent story in La Jolla Light featured Pier Lorenzo Puri, MD, who has spent 28 years researching solutions for Duchenne muscular dystrophy (#DMD). His groundbreaking work led to the FDA approval of Duvyzat, a drug offering a targeted approach to treating DMD—a progressive genetic disorder that causes muscle degeneration. This new treatment, a histone deacetylase inhibitor, provides an alternative to the standard steroid therapy, addressing the disease’s underlying mechanisms rather than simply reducing inflammation. Puri’s commitment to advancing science doesn’t stop here; he’s already exploring new compounds to further improve DMD treatment. https://bit.ly/3FFeeUn #duchennemusculardystrophy #lajolla #sandiego #biomedicalresearch

Register by March 17 for two exciting opportunities later this month for individuals interested in learning more about aging research conducted in San Diego and across the country. ?? ?? On Wednesday, March 26, 2025, the San Diego?Nathan?Shock Center will hold its annual?symposium on “The Heterogeneity of Aging” at the Salk Institute for Biological Studies in the Conrad T. Prebys Auditorium and on Zoom. The La Jolla Aging Meeting follows the next day on Thursday, March 27, 2025. It also will be held at the Salk Institute in the Conrad T. Prebys Auditorium. The event will include scientific presentations and networking with a focus on postdoctoral researchers and students. ?? Learn more: https://vist.ly/3mx5qv3

Check out our latest article, where David Brenner, president and CEO of Sanford Burnham Prebys, shares his perspective on how the National Institutes of Health's (NIH) recent policy shifts are putting vital research, innovation and the future of life-saving medical discoveries at risk. #NIH #indirectcosts #research #medicalresearch #biomedicalresearch

The immune system typically can ramp up the body’s defenses to clear out an invading threat without issue. Glitches can happen, however, with #sepsis occurring when the mustered army of cells also attacks the body’s own tissues and organs as if they were enemy combatants. Sepsis is dangerous, particularly when it isn’t treated early, and it can lead to the even more deadly condition of #septicshock —a massive drop in blood pressure that can quickly damage organs by starving them of nutrients. Scientists at Sanford Burnham Prebys and Advanced Science Research Center, GC/CUNY published findings January 31, 2025, in ACS Omega demonstrating the promise of a new approach to uncovering potential treatments for sepsis. Read more: https://bit.ly/3FfHDEN