Safety Pharmacology Society

??March Webinars You Won’t Want to Miss! ?? Tuesday, March 11 – Early Career Research Showcase Part 3 Featuring: Abel Tasamma (Addis Ababa University), Hayley Woods (Labcorp), and Brigitta Szabó (University of Maastricht) ?? Thursday, March 27 – Pathway to In Silico Trials: Prediction of Cardiac Safety and Efficacy Featuring: Beatriz Trénor Gomis (Universitat Politècnica de València) ?? Register now: https://lnkd.in/gagsn3jg #safetypharmacology #drugdiscovery

?? JOB ALERT ?? A new opportunity has been posted in the SPS Job Bank! ?? Position: Study Director, Safety Pharmacology ?? Location: Madison, Wisconsin ?? Company: Labcorp Looking for your next career move? Explore this and other job opportunities in the SPS Job Bank. ?? Apply:?https://lnkd.in/gkNXb6jc

??February Webinars You Won’t Want to Miss! ?? Tuesday, February 18 – Early Career Research Showcase Part 2 Featuring: Jordan Hawk (Charles River Laboratories), Fatima-Zahra Khamlichi (Boehringer Ingelheim), and Louisa Zolkiewski (Apconix) ?? Thursday, February 20 – Predicting Clinical Outcomes from Secondary Pharmacology Data Featuring: Will Redfern PhD (Certara) ?? Register now: https://lnkd.in/gagsn3jg #safetypharmacology #drugdiscovery

Webinar Alert! Don't miss "Developing a Proteomics-Based Off-Target Identification Assay" on January 30! This webinar will feature two key presentations: 1?? "Developing a Proteomics-based Off-target Identification Assay to Inform Safety Pharmacology Profiling of Targeted Protein Degraders" Sarah Ingersoll, PhD, Amgen 2?? "Comparative Effects in Delaying Repolarization by Small Molecules and an Oligonucleotide in Stem Cell-Derived Cardiomyocytes" Yusheng Qu, PhD, Amgen Inc Targeted protein degraders (TPDs) are a novel therapeutic modality that harnesses the ubiquitin-proteasome system to selectively degrade proteins of interest.?While TPDs offer an innovative approach in drug discovery, these molecules may inadvertently alter the expression of off-target proteins, potentially leading to safety risks. Secondary pharmacology assays for pharmaceuticals, which evaluate the binding or function against off-target proteins, do not fully address the impact of potential off-target degradation by TPDs.?This presentation will outline the development of a novel in vitro assay, where off-target proteins of interest were systematically prioritized from the entire human proteome based on phenotypes from genetic and pharmacological evidence, collectively termed the selected off-target proteome (SOTP). ?? Registration Details: Free for SPS members; fee for non-members Registration closes on January 29! ?? Register now: https://lnkd.in/eBsJjixr #Safetypharmacology #DrugDiscovery #Proteomics #TPDs

Our NEW Early Career Showcase Webinar Series is coming up quickly! Register today and join us on January 21 as we celebrate emerging talent and foster connections within the scientific community. ?? Session 1: Tuesday, January 21, 2025 | 11:00 AM EST ?? Details: Open and free ($0) for all; Registration is required ?? Register now: https://ow.ly/hsNk50UjYF7 #EarlyCareerResearch #drugdiscovery #safetypharmacology

?? Call for Proposals: SPS 2025 Annual Meeting ?? We’re calling on YOU to help shape the 2025 SPS Annual Meeting program in Utrecht, Netherlands! ?? Have innovative ideas to share? ?? Want to present cutting-edge research or lead a workshop? ?? Ready to make an impact on the future of safety pharmacology? Submit your proposals for case studies, workshops, and scientific sessions on topics like: ?? Microphysiological Systems ?? Biological Modelling ?? Novel Modalities ?? Cardiovascular, Respiratory, and CNS Safety Pharmacology …and more! ? Deadline: January 31, 2025 Submit Your Proposal?? https://lnkd.in/g6-DKy_x #SafetyPharmacology #2025SPS #drugdiscovery #NAMs

Sharing another PhD Candidate position! The GENCOR Research Unit of the Faculty of Medicine and Health Sciences (University of Antwerp) is looking for a?full-time (100%) PhD-student?in the field of?cardio-oncology. Prepare your CV and apply below!

?? Introducing the Early Career Showcase Webinar Series! We’re excited to launch a brand-new webinar series dedicated to spotlighting early-career scientists and their innovative research. Join us for three engaging sessions as we celebrate emerging talent and foster connections within the scientific community. ?? Save the Dates: Session 1: Tuesday, January 21, 2025 | 11:00 AM EST Session 2: Tuesday, February 18, 2025 | 11:00 AM EST Session 3: Tuesday, March 18, 2025 | 11:00 AM EDT ?? Details: Open and free ($0) for all; Registration is required Don’t miss these featured presentations—mark your calendar and secure your spot! ?? Register now: https://ow.ly/hsNk50UjYF7 #EarlyCareerResearch #drugdiscovery #safetypharmacology

Join the Conversation! SPS Round Table on Blood Pressure Assessments in Drug Development ?? Date: December 5, 2024 ?? Time: 8:00 AM PST | 11:00 AM EST | 17:00 CET In this round table discussion, experts in the field will address key questions relevant to blood pressure measurements in safety pharmacology. Panelists will also take questions from participants, so this could be an opportunity to get free consulting on programs with complex hemodynamic considerations. From discovery to regulatory considerations, the session will encompass the full spectrum of cardiovascular safety pharmacology. This highly interactive format promises to storm ideas and map potential solutions and industry trends! ?? Featuring: Andrea Greiter-Wilke, PhD, DSP, Roche Innovation Center Basel Lars Johannesen, PhD, FDA Robert Kleiman, MD, Clario Hugo M. Vargas, PhD, DSP, Amgen Don't miss this opportunity to engage with thought leaders and stay ahead in the field of drug development! ?? Register now: https://ow.ly/CRCx50Uhalq #DrugDevelopment #Pharmacology #BloodPressure #SafetyPharmacology

?? Missed #2024SPS in San Diego? Don’t worry—you can still access the cutting-edge insights and industry updates shared at our Annual Meeting! ?? Explore our SPS Annual Meeting: On-Demand and On-Demand+ Posters, available online. ?? Flexible learning at your own pace on any device; access is one year from the purchase date. ?? NEW pricing for Members, Nonmembers, Students, and Retired individuals making it more accessible than ever! ?? Don’t miss this opportunity to learn and expand your expertise. Get started today! https://ow.ly/jWAa50UeaxG #safetypharmacology #drugdiscovery #NAMs #3Rs