Rosetta Commons

We're #hiring The?Rosetta Commons?under the Open Molecular Software Foundation (OMSF) is dedicated to advancing molecular sciences through open science and open-source research software. We're looking for a Technical Product Lead and Documentation Writer. You can learn more on our new jobs page (rosettacommons.org/jobs) and apply here: https://lnkd.in/gSrz9CqF https://lnkd.in/gri87NGG

Finishing up another excellent Winter RosettaCon with the Rosetta Commons. After three post-COVID WRC, I have the full set of winter-themed swag. The science is amazing, but the environment and community is just as fun.

I’m excited to meet this talented Rosetta Commons community tomorrow at our luncheon. I’m looking forward to great conversations and making meaningful connections. #WinterRosettaCon #ProteinDesign #Hiring ??

Calling all computational protein modeling and design enthusiasts! Join us at "Winter RosettaCon 2025" (Rosetta Commons), where experts in #ProteinDesign, deep learning, structural modeling, and enzyme engineering are driving the field forward. At Generate:Biomedicines, we’re applying these advances to program biology and create better medicines with precision and speed. We’re hosting a career lunch, where you can meet our scientists and engineers, learn about our work, and explore opportunities to join our team. Sign up here: https://lnkd.in/eyKAAcuR. We’re hiring across #AI, #MachineLearning, protein science, and computational biology. One of our open roles is Head of Computational Protein Generation, leading research in AI-driven molecular design and biophysics. Learn more about this role and all our open positions by joining us for lunch or visiting our careers page. #ProgrammingBiology | #NowWeCan | #Hiring

It was fun to talk about #machinelearning #proteindesign and #antibodytherapeutics #PMWC2025 PMWC - Precision Medicine World Conference I talked about our lab-in-the-loop approach and specifically highlighted our recent DyAb work that combines smart data augmentation strategies and language models for antibody affinity maturation of developable antibodies. https://lnkd.in/gySvqqcH Genentech Always great to re-unite with other Rosetta Commons members, particularly the brilliant Tanja Kortemme and Brian Weitzner ??

Three days of the Rosetta community uniting for groundbreaking discussions on protein design! ??? #WinterRosettaCon

It was fun to talk about #machinelearning #proteindesign and #antibodytherapeutics #PMWC2025 PMWC - Precision Medicine World Conference I talked about our lab-in-the-loop approach and specifically highlighted our recent DyAb work that combines smart data augmentation strategies and language models for antibody affinity maturation of developable antibodies. https://lnkd.in/gySvqqcH Genentech Always great to re-unite with other Rosetta Commons members, particularly the brilliant Tanja Kortemme and Brian Weitzner ??

The RaMP program is still accepting applications till March 1, 2025. This one-year fellowship program is intended for students to gain research experience to succeed in PhD programs. Learn more here: https://lnkd.in/ggWsMbuj

Earlier this week, members of the Rosetta Commons community and I submitted a public comment in response to the U.S. National Institute of Standards and Technology (NIST) Request for Information on Safety Considerations for Chemical and/or Biological AI Models. Our goal was to share perspectives and considerations that represent the views of Rosetta Commons and of the broader biomolecular structure analysis, prediction, and design communities. It was supplemented by scientists' input from a biosecurity-oriented roundtable discussion at Summer RosettaCon (August 2024), a workshop at European RosettaCon (November 2024), and a survey of the broader Rosetta Commons community. Governments recognize the rapid advancement of biotechnology and are seeking to understand how policies should adapt. In my view, scientific research communities must be meaningfully engaged in policy development processes so that we're equipped to identify and address real risks while supporting vital research, which will, in turn, allow us to tackle major challenges in public health and the environment. In our comment, one issue we draw attention to is the present lack of incentives or straightforward mechanisms to obtain substantive input from scientists on policy matters. While we share some initial thoughts on addressing this challenge, I suspect we're only scratching the surface. I'm eager to hear others' thoughts on bridging this gap. We value feedback from both scientists and policy researchers—please reach out!

Addressing all computational protein modeling and design enthusiasts! Winter RosettaCon 2025 registration closes TOMORROW evening at 11:59 PM EST. You can register and find more information at?www.winterrosettacon.org This Winter Con, we're talking about: - Protein design with Rosetta and deep learning - Structural modeling of proteins, protein-ligand interactions, antibodies, membrane proteins, protein-nucleic acid complexes, and all other things you like to model - Antibody and vaccine design - Enzyme design - AlphaFold, ESMFold, RoseTTAFold, ProteinMPNN, language models for structure prediction and design - Code development and community involvement