RoosterBio Inc.

RoosterBio cells and media outperform the industry competition, as shown in this time-lapse comparison following 2 cell systems over 2 passages. Thanks to years of formula and process optimization, RoosterBio cells are expanded and ready in fewer days with 0 media exchanges. This means reduced media usage, expansion time, and overall cost. Watch it here: https://lnkd.in/edWguSQb #bioprocessmedia #cellculturemedia #bioprocessing #cellexpansion #mediaexchange #celltherapy #bioprocess #cellandgenetherapy #xenofree

RoosterNourish? is the industry’s best-performing bioprocess media used for MSC, iPSC-derived MSC, and #fibroblast expansion. Years of formula and process optimization have increased productivity and upper limits of achievable scale, while drastically reducing costs and expansion time by up to 60%. Learn how RoosterNourish can upgrade the way you culture cells: https://lnkd.in/gbqHgZQ7 #stemcelltherapy #stemcells #bioprocessing #bioprocessmedia #cellculture #celltherapymanufacturing #mesenchymalstemcells #regenerativemedicine

?? As published in the #preprint journal bioRxiv, researchers at the University of Wisconsin-Madison developed a method to screen cancer-targeted theranostics using a library of phage VNAR shark antibodies directed at #fibroblast activation protein (FAP), which helps tumors grow. VNAR-Fc fusion constructs selectively bound to FAP+ xenografts with high affinity, enabling a new discovery platform for targeting prostate tumor microenvironments. This new approach could lead to better cancer treatments by improving how tumors are diagnosed and targeted. RoosterBio was happy to observe RoosterNourish? medium prove satisfactory for the culture of hPrCSC-44 prostate cancer fibroblasts. Read it here: https://lnkd.in/emCTZY7g #antibodies #microenvironment #cellculture #bioprocessmedia #theranostic #biorxiv #cancerresearch #vnar #tumors #fibroblasts

To maximize therapeutic potential, #extracellularvesicles (EVs) from mesenchymal stromal cells (MSCs) need established quality attributes. Join us on Wednesday, April 2nd at 11:00 AM (ET) to learn how analytical tools can assess the impact of production process choices and tissue source on the quality attributes of MSC-EVs. Webinar topics will include: ?? An overview of a standardized but flexible EV production process. ?? Advanced analytical assessment of quality attributes of EVs. ?? The impact of key factors such as production decisions and tissue source on EV attributes. Register here: https://lnkd.in/er3g4KUs #exosomes #regenerativemedicine #celltherapy #stemcells #cellculture #stemcelltherapy #advancedtherapies #assaydevelopment

To unlock the full potential of #extracellularvesicles, MSC-EV production must align with CMC and regulatory standards. RoosterBio's latest study compares conditioned medium across scalable platforms to optimize MSC-EV manufacturing for the clinic. Explore our findings here: https://lnkd.in/emmvf9XW #exosomes #bioprocess #celltherapy #cellculture #bioassays #cellbasedassays #cd73 #bioreactors #microvesicles #cellandgenetherapy #researchanddevelopment

Last year, RoosterBio and Cytiva hosted a webinar to share our collaboration's breakthroughs to scale #exosome production for therapeutic use, blending RoosterBio's upstream MSC expansion expertise with Cytiva's #downstreamprocessing technologies. The optimized combined workflow demonstrates a scalable, clinically relevant solution that preserves exosome purity and potency. This streamlined platform can address critical industry needs to make exosome-based therapies more accessible and feasible at larger scales. Watch the webinar on-demand and read the accompanying blog here: https://lnkd.in/eyMcWPyJ #extracellularvesicles #bioprocessing #bioprocess #celltherapy #advancedtherapies #celltherapymanufacturing #regenerativemedicine

?? A study published in Science Advances from Oregon Health & Science University, Wyss Institute at Harvard University, and State University of Campinas shows that perivascular cells (PCs) play a crucial role in how tiny blood vessels respond to changes in their surroundings. Using lab-engineered capillaries, the group led by Professor Luiz Bertassoni found that PCs influence vessel leakage and inflammation, especially in stiffened, diseased tissues. The findings highlight a new, possibly targetable mechanism via NOTCH3 to modulate vascular health in diseases like atherosclerosis, neurodegeneration or liver fibrosis. RoosterBio was pleased to see its MSCs used in the methods of this work. Read it here: https://lnkd.in/e9V4_tdT #capillary #pericytes #mesenchymalstemcells #fibrosis #perivascularcells #liverfibrosis #celltherapyresearch #inflammation #celltherapy

??? Join RoosterBio's upcoming webinar, Exploring MSC-EV Attributes: Analytical Comparison of Tissue Sources and Production Platforms, on Wednesday, April 2nd at 11:00 AM (ET). To maximize therapeutic potential, #extracellularvesicles (EVs) from mesenchymal #stromalcells (MSCs) need established quality attributes. This webinar will explore how analytical tools can assess the impact of production process choices and tissue source on the quality attributes of MSC-derived EVs. Register here: https://lnkd.in/eZnYmy4V #criticalqualityattributes #advancedtherapies #exosomes #stemcelltherapy #cqas #bioproduction #bioprocessing #celltherapymanufacturing

Biological components in conditioned media are a consistent problem during downstream processing of #exosomes. That's why RoosterBio developed AgentV?-DSP, a solution designed to address filtration problems and increase particle yield up to 10-fold. Watch our latest webinar on-demand to learn more: https://lnkd.in/eH8BhX-s #Extracellularvesicles #downstreamprocessing #webinar #exosome #microvesicles #bioprocessing #bioprocess

QuickShip? DSP takes conditioned media and rapidly processes it into vials of either concentrated extracellular vesicles/enriched secretome or purified extracellular vesicles. Learn how to leverage RoosterBio's advanced equipment and industry-leading expertise to enable faster results without needing to acquire complex downstream processing capabilities.?? https://lnkd.in/e8aTQRPT #extracellularvesicles #exosomes #downstreamprocessing #bioprocessdevelopment #celltherapy #secretome #advancedtherapies